Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in pulmonary arterial hypertension.

Autor: Reyes-Palomares A; European Molecular Biology Laboratory, Structural and Computational Biology Unit, Meyerhofstrasse 1, 69115, Heidelberg, Germany.; Department of Biochemistry and Molecular Biology, Complutense University of Madrid, 28040, Madrid, Spain., Gu M; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Grubert F; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Berest I; European Molecular Biology Laboratory, Structural and Computational Biology Unit, Meyerhofstrasse 1, 69115, Heidelberg, Germany., Sa S; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Kasowski M; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Arnold C; European Molecular Biology Laboratory, Structural and Computational Biology Unit, Meyerhofstrasse 1, 69115, Heidelberg, Germany., Shuai M; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Srivas R; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Miao S; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Li D; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Snyder MP; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. mpsnyder@stanford.edu., Rabinovitch M; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. marlener@stanford.edu., Zaugg JB; European Molecular Biology Laboratory, Structural and Computational Biology Unit, Meyerhofstrasse 1, 69115, Heidelberg, Germany. judith.zaugg@embl.de.

Publikováno v: Nature communications [Nat Commun] 2020 Apr 03; Vol. 11 (1), pp. 1673. Date of Electronic Publication: 2020 Apr 03.

Enhancing RNA-seq analysis by addressing all co-existing biases using a self-benchmarking approach with 2D structural insights.

Autor: Su, Qiang^1,2 (AUTHOR) su@chemie.uni-siegen.de, Long, Yi³ (AUTHOR), Gou, Deming⁴ (AUTHOR), Quan, Junmin² (AUTHOR) su@chemie.uni-siegen.de, Lian, Qizhou^1,5,6 (AUTHOR) su@chemie.uni-siegen.de

Publikováno v: Briefings in Bioinformatics. Nov2024, Vol. 25 Issue 6, p1-13. 13p.

The 3D Genome in Brain Development: An Exploration of Molecular Mechanisms and Experimental Methods.

Autor: Rahman, Samir^1,2,3,4,5 (AUTHOR) rahman.samir33@gmail.com, Roussos, Panos^{1,2,3,4,5,6,7} (AUTHOR)

Publikováno v: Neuroscience Insights. 10/29/2024, p1-15. 15p.

Landscape of cohesin-mediated chromatin loops in the human genome.

Autor: Grubert F; Department of Genetics, Stanford University School of Medicine, Palo Alto, CA, USA.; Department of Pathology, Stanford University School of Medicine, Palo Alto, CA, USA., Srivas R; Department of Genetics, Stanford University School of Medicine, Palo Alto, CA, USA., Spacek DV; Department of Genetics, Stanford University School of Medicine, Palo Alto, CA, USA., Kasowski M; Department of Genetics, Stanford University School of Medicine, Palo Alto, CA, USA.; Department of Pathology, Stanford University School of Medicine, Palo Alto, CA, USA., Ruiz-Velasco M; Structural and Computational Biology, European Molecular Biology Laboratory, Heidelberg, Germany., Sinnott-Armstrong N; Department of Genetics, Stanford University School of Medicine, Palo Alto, CA, USA., Greenside P; Biomedical Informatics Graduate Training Program, Stanford University School of Medicine, Stanford, CA, USA., Narasimha A; Department of Genetics, Stanford University School of Medicine, Palo Alto, CA, USA., Liu Q; Department of Genetics, Stanford University School of Medicine, Palo Alto, CA, USA., Geller B; Department of Genetics, Stanford University School of Medicine, Palo Alto, CA, USA., Sanghi A; Department of Genetics, Stanford University School of Medicine, Palo Alto, CA, USA., Kulik M; Center for Molecular Medicine, University of Georgia, Athens, GA, USA.; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, USA., Sa S; Vera Moulton Wall Center for Pulmonary Vascular Diseases, Stanford University School of Medicine, Palo Alto, CA, USA.; Stanford Cardiovascular Institute, Stanford University School of Medicine, Palo Alto, CA, USA.; Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA, USA., Rabinovitch M; Vera Moulton Wall Center for Pulmonary Vascular Diseases, Stanford University School of Medicine, Palo Alto, CA, USA.; Stanford Cardiovascular Institute, Stanford University School of Medicine, Palo Alto, CA, USA.; Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA, USA., Kundaje A; Department of Genetics, Stanford University School of Medicine, Palo Alto, CA, USA.; Department of Computer Science, Stanford University, Stanford, CA, USA., Dalton S; Center for Molecular Medicine, University of Georgia, Athens, GA, USA.; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, USA., Zaugg JB; Structural and Computational Biology, European Molecular Biology Laboratory, Heidelberg, Germany., Snyder M; Department of Genetics, Stanford University School of Medicine, Palo Alto, CA, USA. mpsnyder@stanford.edu.

Publikováno v: Nature [Nature] 2020 Jul; Vol. 583 (7818), pp. 737-743. Date of Electronic Publication: 2020 Jul 29.

G-quadruplexes as pivotal components of cis-regulatory elements in the human genome.

Autor: Zhang, Rongxin^1,2 (AUTHOR), Wang, Yuqi² (AUTHOR), Wang, Cheng^3,4 (AUTHOR), Sun, Xiao² (AUTHOR) xsun@seu.edu.cn, Mergny, Jean-Louis¹ (AUTHOR) jean-louis.mergny@polytechnique.edu

Publikováno v: BMC Biology. 8/26/2024, Vol. 22 Issue 1, p1-23. 23p.