Zobrazeno 1 - 10
of 415
pro vyhledávání: '"Gruber Helen E"'
Publikováno v:
Molecular Pain, Vol 8, Iss 1, p 63 (2012)
Abstract Background In spite of its high clinical relevance, the relationship between disc degeneration and low back pain is still not well understood. Recent studies have shown that genome-wide gene expression studies utilizing ontology searches pro
Externí odkaz:
https://doaj.org/article/cae5969ea01f44aea1c336c338c1775a
Autor:
Gruber Helen E, Tinder Teresa L, Pathangey Latha B, Ghosh Sriparna, Roy Lopamudra, Mukherjee Pinku
Publikováno v:
BMC Cancer, Vol 11, Iss 1, p 365 (2011)
Abstract Background Several studies have demonstrated that sites of chronic inflammation are often associated with the establishment and growth of various malignancies. A common inflammatory condition in humans is autoimmune arthritis (AA). Although
Externí odkaz:
https://doaj.org/article/e499afc4503c41dfa8142dd26794c36a
Autor:
Norton James H, Kneisl Jeffrey S, Honeycutt Patrick R, Mauerhan David R, Sun Yubo, Hanley Edward N, Gruber Helen E
Publikováno v:
BMC Musculoskeletal Disorders, Vol 11, Iss 1, p 19 (2010)
Abstract Background Menisci play a vital role in load transmission, shock absorption and joint stability. There is increasing evidence suggesting that OA menisci may not merely be bystanders in the disease process of OA. This study sought: 1) to dete
Externí odkaz:
https://doaj.org/article/02f930f4405e453498ba1fe70d62b930
Publikováno v:
BMC Biotechnology, Vol 10, Iss 1, p 5 (2010)
Abstract Background Senescent cells are well-recognized in the aging/degenerating human disc. Senescent cells are viable, cannot divide, remain metabolically active and accumulate within the disc over time. Molecular analysis of senescent cells in ti
Externí odkaz:
https://doaj.org/article/0bc699b8b4b34ecdac419123124856ab
Autor:
Norton H James, Ingram Jane A, Chow Yin, Mauerhan David, Gruber Helen E, Hanley Edward N, Sun Yubo
Publikováno v:
BMC Biotechnology, Vol 8, Iss 1, p 54 (2008)
Abstract Background The meniscus is a complex tissue whose cell biology has only recently begun to be explored. Published models rely upon initial culture in the presence of added growth factors. The aim of this study was to test a three-dimensional
Externí odkaz:
https://doaj.org/article/bef045d1bebf444592ae1c703db811cb
Publikováno v:
Nutrition & Metabolism, Vol 2, Iss 1, p 24 (2005)
Abstract Background Epidemiological studies have linked low dietary magnesium (Mg) to low bone mineral density and osteoporosis. Mg deficiency in animal models has demonstrated a reduction in bone mass and increase in skeletal fragility. One major me
Externí odkaz:
https://doaj.org/article/6bce70fc59bd4b549e9e0bea5f3e3adb
Publikováno v:
BMC Musculoskeletal Disorders, Vol 4, Iss 1, p 7 (2003)
Abstract Background Dietary magnesium (Mg) deficiency in the mouse perturbs bone and mineral homeostasis. The objective of the present study was to evaluate bone mineral density of the femur in control and Mg-deficient mice. Methods BALB/c mice aged
Externí odkaz:
https://doaj.org/article/8994ca4a422f4e9da9f6397d4b884ee6
Publikováno v:
BMC Musculoskeletal Disorders, Vol 4, Iss 1, p 4 (2003)
Abstract Background The purpose of this study is to present an automated system that analyzes digitized x-ray images of small animal spines identifying the effects of disc degeneration. The age-related disc and spine degeneration that occurs in the s
Externí odkaz:
https://doaj.org/article/21102a4a0c6147f38566d78eae83217c
Autor:
Hanley Edward N, Gruber Helen E
Publikováno v:
BMC Musculoskeletal Disorders, Vol 3, Iss 1, p 9 (2002)
Abstract Background In the annulus, collagen fibers that make up the lamellae have a wavy, planar crimped pattern. This crimping plays a role in disc biomechanical function by allowing collagen fibers to stretch during compression. The relationship b
Externí odkaz:
https://doaj.org/article/8f05234bf45a406bb3bff4d8de4e0756
Autor:
Leslie Kelly, Ingram Jane, Yamaguchi Dean, Gruber Helen E, Huang Weibiao, Miller Timothy A, Hanley Edward N
Publikováno v:
BMC Musculoskeletal Disorders, Vol 3, Iss 1, p 4 (2002)
Abstract Background Recent evidence suggests that estrogens exert effects in different tissues throughout the body, and that the estrogen receptor β (ERβ) may be important for the action of estrogen (17-β-estradiol) on the skeleton. The cellular l
Externí odkaz:
https://doaj.org/article/754a10a2b87f493baca0383ee758baa3