Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Growth hormone receptor binding"'
Publikováno v:
AGE. 36:117-127
Neuromusculoskeletal (physical) frailty is an aging-attributable biomedical issue of extremely high import, from both public health and individual perspectives. Yet, it is rarely studied in nonhuman research subjects and very rarely studied in animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff90d77564c75ddc357741cec153ea6
https://doi.org/10.1007/s11357-013-9551-x
https://doi.org/10.1007/s11357-013-9551-x
Publikováno v:
Growth Hormone & IGF Research. 17:346-351
Growth hormone's (GH) lipolytic activity in white adipose tissue (WAT) results in decreased body fat in giant GH transgenic mice and increased subcutaneous fat in dwarf growth hormone receptor/binding protein gene-disrupted mice (GHR -/-). We therefo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8ff1ce7a27eb7dfdbb768420e0850a
https://doi.org/10.1016/j.ghir.2007.04.006
https://doi.org/10.1016/j.ghir.2007.04.006
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 6 (2015)
Frontiers in Microbiology, Vol 6 (2015)
A variety of mycoviruses have been found in Sclerotinia sclerotiorum. In this study, we report a novel mycovirus Sclerotinia sclerotiorum botybirnavirus 1 (SsBRV1) that was originally isolated from the hypovirulent strain SCH941 of S. sclerotiorum. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de64efd91d6ddcd9f55d29f6065e13f1
https://doi.org/10.3389/fmicb.2015.00406
https://doi.org/10.3389/fmicb.2015.00406
Autor:
Karen T. Coschigano
Publikováno v:
AGE. 28:191-200
Since generation of the growth hormone receptor/binding protein (GHR/BP) gene-disrupted mouse nearly 10 years ago, use of this mouse model has become widespread in the elucidation of the physiological roles of GH and insulin-like growth factor-1 (IGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b8c24c4e3b6e6eea09d4c5ba3e5de5
https://doi.org/10.1007/s11357-006-9004-x
https://doi.org/10.1007/s11357-006-9004-x
Publikováno v:
Hormone and Metabolic Research. 34:481-486
Numerous studies have shown that the lifespan can be extended by caloric restriction or by altering the growth hormone (GH)-insulin-like growth factor 1 signaling pathway. Both of these manipulations produce physiological alterations, such as increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80b0b6312adc9f04c875666cbe92a7a
https://doi.org/10.1055/s-2002-34787
https://doi.org/10.1055/s-2002-34787
Autor:
Andrzej Bartke, Jeremy G. Turner, Jamal K. Saleh, Romesh Khardori, Ravneet K. Boparai, John J. Kopchick, Oge Arum
Publikováno v:
F1000Research
The correlation of physiological sensitivity to insulin (vis-à-vis glycemic regulation) and longevity is extensively established, creating a justifiable gerontological interest on whether insulin sensitivity is causative, or even predictive, of some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4915a6a20fffa5509d3057bdcbd2c221
https://pubmed.ncbi.nlm.nih.gov/25789159
https://pubmed.ncbi.nlm.nih.gov/25789159
Publikováno v:
Experimental Biology and Medicine. 226:552-558
The mechanisms that are responsible for the extension of lifespan in the mouse with targeted disruption (knockout [KO]) of the growth hormone (GH) receptor/binding protein (GHR-KO) are unknown. However, in the long-living Ames dwarf mouse, blood gluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca68f725dea2f822cf1b73e62b28b3db
https://doi.org/10.1177/153537020122600607
https://doi.org/10.1177/153537020122600607
Publikováno v:
Molecular Genetics and Metabolism. 73:1-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d142d1ac758019c7610aa5fbf3707a00
https://doi.org/10.1006/mgme.2001.3164
https://doi.org/10.1006/mgme.2001.3164
Autor:
Liliane J. Striker, Sophie Doublier, Gary E. Striker, Amy N. Holland, Linda L. Bellush, John J. Kopchick
Publikováno v:
Endocrinology. 141:163-168
To further investigate the role of GH in diabetic nephropathy, experimental diabetes was induced with streptozotocin (STZ) in mice in which the GH receptor/binding protein gene was disrupted. Body weight, blood glucose, and renal histology and morpho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff88e00a17a6fe019b94e69acd54aa39
https://doi.org/10.1210/endo.141.1.7284
https://doi.org/10.1210/endo.141.1.7284
Autor:
Fred Nyberg
Publikováno v:
Experimental Gerontology. 32:521-528
Recent years have seen an increasing interest in research focused on the role that growth hormone (GH) may have in the central nervous system. The psychological improvements seen in adults following GH therapy combined with the observation that the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162648b36883e53ddbaf4e07c8dc0296
https://doi.org/10.1016/s0531-5565(96)00170-2
https://doi.org/10.1016/s0531-5565(96)00170-2