Zobrazeno 1 - 10
of 12 326
pro vyhledávání: '"Growth hormone/deficiency"'
Publikováno v:
International Journal of Retina and Vitreous, Vol 10, Iss 1, Pp 1-6 (2024)
Abstract Background The purpose of this study is to evaluate the retinal and choroidal microvascular state in children with congenital isolated growth hormone deficiency (IGHD) and determine the effect of recombinant human growth hormone treatment on
Externí odkaz:
https://doaj.org/article/b247e1063a5342278c09b94a18daca18
Autor:
Xiaonan Guo, Shanshan Liu, Wenjing Hu, Xiaorui Lyu, Hanyuan Xu, Huijuan Zhu, Hui Pan, Linjie Wang, Yu Wan, Hongbo Yang, Fengying Gong
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Adult growth hormone deficiency (AGHD) is associated with an increased risk of fractures and impaired bone microstructure. Understanding the metabolic changes accompanying bone deterioration in AGHD might provide insights into mec
Externí odkaz:
https://doaj.org/article/26235916443445b5aa6e27b102c36626
Autor:
Akhtar S, Berg B, Medina J, Gonczi MN, Hamilton S, Hildebrand E, Kelepouris N, Neergaard JS, Sværke C, Ter-Borch G, Rasmussen NK
Publikováno v:
Medical Devices: Evidence and Research, Vol Volume 17, Pp 427-439 (2024)
Shahid Akhtar,1 Birgitte Berg,2 Johan Medina,3 Maya Nicole Gonczi,4 Sophie Hamilton,5 Emily Hildebrand,4 Nicky Kelepouris,6 Jesper Skov Neergaard,7 Claus Sværke,8 Gitte Ter-Borch,2 Niklas Kahr Rasmussen3 1Devices & Digital Health, Novo Nordisk A/S,
Externí odkaz:
https://doaj.org/article/6a5c5a7dfa7a42059cd6600944db9b4b
Publikováno v:
Endocrines, Vol 5, Iss 3, Pp 341-353 (2024)
Growth hormone deficiency (GHD) is the most frequent pituitary hormone deficiency in childhood, with an incidence of 1 in 4000–10,000 live births. GHD can be congenital (genetic or due to hypothalamic/pituitary abnormalities) or acquired and can be
Externí odkaz:
https://doaj.org/article/50c95fa1d5504c9ea8e0a3aed78832ff
Autor:
Lukas Plachy, Petra Dusatkova, Klara Maratova, Shenali Anne Amaratunga, Dana Zemkova, Vit Neuman, Stanislava Kolouskova, Barbora Obermannova, Marta Snajderova, Zdenek Sumnik, Jan Lebl, Stepanka Pruhova
Publikováno v:
Endocrine Connections, Vol 13, Iss 10, Pp 1-8 (2024)
Because the causes of combined pituitary hormone deficiency (CPHD) are complex, the etiology of congenital CPHD remains unknown in most cases. The aim of the study was to identify the genetic etiology of CPHD in a well-defined single-center cohort. I
Externí odkaz:
https://doaj.org/article/bd019d5695e14abdacc13ff0b6d850ca
Altered individual-level morphological similarity network in children with growth hormone deficiency
Autor:
Yanglei Cheng, Liping Lin, Weifeng Hou, Huaqiong Qiu, Chengfen Deng, Zi Yan, Long Qian, Wei Cui, Yanbing Li, Zhiyun Yang, Qiuli Chen, Shu Su
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Accumulating evidences indicate regional grey matter (GM) morphology alterations in pediatric growth hormone deficiency (GHD); however, large-scale morphological brain networks (MBNs) undergo these patients remains unclear. Object
Externí odkaz:
https://doaj.org/article/9c48c35222ef49bca086993f7b41e459
Autor:
Kevin C. J. Yuen, Rikke Hjortebjerg, Ashok Ainkaran Ganeshalingam, David R. Clemmons, Jan Frystyk
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Growth hormone (GH) is the key regulator of insulin-like growth factor I (IGF-I) generation in healthy states. However, portal insulin delivery is also an essential co-player in the regulation of the GH/IGF-I axis by affecting and regulating hepatic
Externí odkaz:
https://doaj.org/article/56562f1fe86146629b2fb6d5a7e535dc
Autor:
Xiaozhen Huang, Hong Chen, Huakun Shangguan, Wenyong Wu, Zhuanzhuan Ai, Zhifeng Chen, Ruimin Chen
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundIsolated growth hormone deficiency type II (IGHD II) is an autosomal dominant disorder characterized by a GH1 gene variant resulting in a significant reduction in growth hormone (GH) secretion and a subsequent decrease of plasma insulin-lik
Externí odkaz:
https://doaj.org/article/48b49923f03845f89fd8209d571ba1a4
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 291-306 (2024)
Bradley S Miller,1 Jo Blair,2 Reiko Horikawa,3 Agnès Linglart,4– 7 Kevin CJ Yuen8 1Division of Pediatric Endocrinology, University of Minnesota Medical School, MHealth Fairview Masonic Children’s Hospital, Minneapolis, MN, USA; 2Department of Pa
Externí odkaz:
https://doaj.org/article/0214bae3491f403ead5e55f7a37334a9