Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Growth Hormone/administration & dosage"'
Autor:
Reid Aikin, Norbert Baume, Antoni Pastor, Osquel Barroso, Mario Thevis, Tiia Kuuranne, Tristan Equey, Andreas Thomas, Rafael de la Torre Fornell, Sylvain Giraud
Publikováno v:
The Journal of clinical endocrinology and metabolism, vol. 107, no. 3, pp. 649-659
Context Because of its anabolic and lipolytic properties, growth hormone (GH) use is prohibited in sport. Two methods based on population-derived decision limits are currently used to detect human GH (hGH) abuse: the hGH Biomarkers Test and the Isofo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5614e0621da196a43f3d0f4d3feddd
http://hdl.handle.net/10230/54011
http://hdl.handle.net/10230/54011
Autor:
Mathilde Gersel Wegmann, Guftar Shaikh, Olle Söder, Sten A. Ivarsson, Edna Roche, Jeremy Kirk, Anders Juul, David B. Dunger, Hilary Hoey, Rikke Beck Jensen, Ajay Thankamony, Jan Frystyk
Publikováno v:
Wegmann, M G, Jensen, R B, Thankamony, A, Frystyk, J, Roche, E, Hoey, H, Kirk, J, Shaikh, G, Ivarsson, S-A, Söder, O, Dunger, D B & Juul, A 2020, ' Increases in bioactive IGF do not parallel increases in total IGF-I during growth hormone treatment of children born SGA ', The Journal of clinical endocrinology and metabolism, vol. 105, no. 4, dgz118, pp. E1291-E1298 . https://doi.org/10.1210/clinem/dgz118
Wegmann, M G, Jensen, R B, Thankamony, A, Frystyk, J, Roche, E, Hoey, H, Kirk, J, Shaikh, G, Ivarsson, S-A, Söder, O, Dunger, D B & Juul, A 2020, ' Increases in bioactive IGF do not parallel increases in total IGF-I during growth hormone treatment of children born SGA ', The Journal of clinical endocrinology and metabolism, vol. 105, no. 4, dgz118 . https://doi.org/10.1210/clinem/dgz118
Wegmann, M G, Jensen, R B, Thankamony, A, Frystyk, J, Roche, E, Hoey, H, Kirk, J, Shaikh, G, Ivarsson, S-A, Söder, O, Dunger, D B & Juul, A 2020, ' Increases in Bioactive IGF do not Parallel Increases in Total IGF-I During Growth Hormone Treatment of Children Born SGA ', Journal of Clinical Endocrinology and Metabolism, vol. 105, no. 4, pp. e1291–e1298 . https://doi.org/10.1210/clinem/dgz118
Wegmann, M G, Jensen, R B, Thankamony, A, Frystyk, J, Roche, E, Hoey, H, Kirk, J, Shaikh, G, Ivarsson, S-A, Söder, O, Dunger, D B & Juul, A 2020, ' Increases in bioactive IGF do not parallel increases in total IGF-I during growth hormone treatment of children born SGA ', The Journal of clinical endocrinology and metabolism, vol. 105, no. 4, dgz118 . https://doi.org/10.1210/clinem/dgz118
Wegmann, M G, Jensen, R B, Thankamony, A, Frystyk, J, Roche, E, Hoey, H, Kirk, J, Shaikh, G, Ivarsson, S-A, Söder, O, Dunger, D B & Juul, A 2020, ' Increases in Bioactive IGF do not Parallel Increases in Total IGF-I During Growth Hormone Treatment of Children Born SGA ', Journal of Clinical Endocrinology and Metabolism, vol. 105, no. 4, pp. e1291–e1298 . https://doi.org/10.1210/clinem/dgz118
Background Some children born small for gestational age (SGA) experience supra-physiological insulin-like growth factor-I (IGF-I) concentrations during GH treatment. However, measurements of total IGF-I concentrations may not reflect the bioactive fr
Autor:
Michael Højby Rasmussen, Djordje Marina, Ulla Feldt-Rasmussen, Mette Tanvig, Marianne Klose, Marianne Andersen, Lene From Nielsen, Jurgita Janukonyte, Jens Sandahl Christiansen, Charlotte Höybye
Publikováno v:
Rasmussen, M H, Janukonyte, J, Klose, M, Marina, D, Tanvig, M H, Nielsen, L F, Höybye, C, Andersen, M, Feldt-Rasmussen, U & Christiansen, J S 2016, ' Reversible Albumin-Binding GH Possesses a Potential Once-Weekly Treatment Profile in Adult Growth Hormone Deficiency ', Journal of Clinical Endocrinology and Metabolism, vol. 101, no. 3, pp. 988–998 . https://doi.org/10.1210/jc.2015-1991
Rasmussen, M H, Janukonyté, J, Klose, M, Marina, D, Tanvig, M, Nielsen, L F, Höybye, C, Andersen, M, Feldt-Rasmussen, U & Christiansen, J S 2016, ' Reversible albumin-binding GH possesses a potential once-weekly treatment profile in adult growth hormone deficiency ', Journal of Clinical Endocrinology and Metabolism, vol. 101, no. 3, pp. 988-998 . https://doi.org/10.1210/jc.2015-1991
Rasmussen, M H, Janukonyté, J, Klose, M, Marina, D, Tanvig, M, Nielsen, L F, Höybye, C, Andersen, M, Feldt-Rasmussen, U & Christiansen, J S 2016, ' Reversible albumin-binding GH possesses a potential once-weekly treatment profile in adult growth hormone deficiency ', Journal of Clinical Endocrinology and Metabolism, vol. 101, no. 3, pp. 988-998 . https://doi.org/10.1210/jc.2015-1991
Context: NNC0195-0092 is a reversible, albumin-binding GH derivative, developed for once-weekly administration. Objectives: The objective of the study was to evaluate safety, local tolerability, pharmacodynamics, and pharmacokinetics of multiple, onc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f428bdeabae341b8e4d25dbebab962a
https://portal.findresearcher.sdu.dk/da/publications/1cb82f1d-6dd2-4572-a250-1d7b69fbb3eb
https://portal.findresearcher.sdu.dk/da/publications/1cb82f1d-6dd2-4572-a250-1d7b69fbb3eb
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics, Vol. 78, No 2 (2011) pp. 278-88
The availability of recombinant human growth hormone (GH) has broadened its range of clinical applications. Approved indications for GH therapy include treatment of growth hormone deficiency (in children and in adults), Turner syndrome, Prader-Willi
Publikováno v:
Journal of Bone and Mineral Research, Vol. 17, no. 6, p. 1081-1094 (2002)
Adult hypopituitary patients with growth hormone deficiency (GHD) show a significant decrease in bone mass and an increased fracture rate. Replacement therapy with GH increases bone turnover. Most of the long-term data on bone mineral content (BMC) a
Autor:
Dominique Smeets, Henri J L M Timmers, Vedat Topsakal, Sabine M.P.F. de Muinck Keizer-Schrama, Ronald J.E. Pennings, Ronald J.C. Admiraal, Jan M. Wit, Leonie A. Menke, K. Freriks, Henricus P. M. Kunst, Ad R. M. M. Hermus, Patrick L. M. Huygen, Theo C J Sas, Janiëlle A E M van Alfen-van der Velden, Eva J J Verver, Barto J. Otten
Publikováno v:
Otology and Neurotology, 35(9), 1577-1584. Lippincott Williams and Wilkins
Otology and Neurotology, 35(9), 1577-1584
Otology & Neurotology, 35, 9, pp. 1577-84
Otology & Neurotology, 35, 1577-84
Otology and Neurotology, 35(9), 1577-1584
Otology & Neurotology, 35, 9, pp. 1577-84
Otology & Neurotology, 35, 1577-84
Item does not contain fulltext OBJECTIVE: To evaluate karyotype-specific ear and hearing problems in young-adult patients with Turner syndrome (TS) and assess the effects of previous treatment with oxandrolone (Ox). STUDY DESIGN: Double-blind follow-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7765b898955e12e0b16d48fef068b36
https://pure.amc.nl/en/publications/karyotypespecific-ear-and-hearing-problems-in-young-adults-with-turner-syndrome-and-the-effect-of-oxandrolone-treatment(64b5e939-ac87-43e7-90ac-d6720ec3993d).html
https://pure.amc.nl/en/publications/karyotypespecific-ear-and-hearing-problems-in-young-adults-with-turner-syndrome-and-the-effect-of-oxandrolone-treatment(64b5e939-ac87-43e7-90ac-d6720ec3993d).html
Autor:
Anders Ploug Boesen, Peter Schjerling, Kasper Dideriksen, Per Aagaard, Henning Langberg, Stig Peter Magnusson, Michael Kjaer, Christian Couppé, Mikael Boesen
Publikováno v:
Boesen, A P, Dideriksen, K J, Couppe, C, Magnusson, S P, Schjerling, P, Boesen, M, Aagaard, P, Kjaer, M & Langberg, H 2014, ' Effect of growth hormone on aging connective tissue in muscle and tendon-gene expression, morphology and function following immobilization and rehabilitation ', Journal of Applied Physiology, vol. 116, no. 2, pp. 192-203 . https://doi.org/10.1152/japplphysiol.01077.2013
It is unknown whether loss in musculotendinous tissue during inactivity can be counteracted by growth hormone (GH), and whether GH accelerate rehabilitation in aging individuals. Elderly men (65–75 yr; n = 12) had one leg immobilized 2 wk followed
Publikováno v:
European journal of endocrinology. 165(3)
ObjectiveGH replacement therapy currently requires daily injections, which may be inconvenient and distressing for young patients. This study determined the safety, tolerability, pharmacokinetics and pharmacodynamics of escalating single doses of a p
Autor:
G. C. B. (Karen) Bindels-de Heus, Gianni Bocca, Elbrich P. C. Siemensma, E. C. A. Mieke Houdijk, Rene C. F. M. Vreuls, J. J. Gera Hoorweg-Nijman, Stenvert L. S. Drop, E J Schroor, A S Paul van Trotsenburg, Jan M. Wit, Dederieke A. M. Festen, R. J. Odink, Jan Willem Pilon, Barto J. Otten, Joost Rotteveel, Mariettee van Leeuwen, Anita C. S. Hokken-Koelega, Edgar van Mil, Boudewijn Bakker, Danny A. J. P. Haring, Roderick F. A. de Lind van Wijngaarden, Petr E. Jira
Publikováno v:
Journal of Clinical Endocrinology & Metabolism, 94(11), 4205-15. Oxford University Press
Journal of Clinical Endocrinology and Metabolism, 94(11), 4205-4215. Endocrine Society
Journal of clinical endocrinology and metabolism, 94(11), 4205-4215. The Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 94, 11, pp. 4205-15
Journal of Clinical Endocrinology and Metabolism, 94, 4205-15
Journal of Clinical Endocrinology and Metabolism, 94(11), 4205-4215. ENDOCRINE SOC
de Lind van Wijngaarden, R F A, Siemensma, E P C, Festen, D A M, Otten, B J, van Mil, E G A H, Rotteveel, J, Odink, R J H, van Bindels-de Heus, G C B, Leeuwen, M, Haring, D A P J, Bocca, G, Houdijk, E C A M, Hoorweg-Nijman, J J G, Vreuls, R C F M, Jira, P E, Trotsenburg, A S P, Bakker, B, Schroor, E J, Pilon, J W, Wit, J M, Drop, S L S & Hokken-Koelega, A C S 2009, ' Efficacy and Safety of Long-Term Continuous Growth Hormone Treatment in Children with Prader-Willi Syndrome ', Journal of Clinical Endocrinology and Metabolism, vol. 94, no. 11, pp. 4205-4215 . https://doi.org/10.1210/jc.2009-0454
Journal of Clinical Endocrinology and Metabolism, 94(11), 4205-4215. The Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 94(11), 4205-4215. Endocrine Society
Journal of clinical endocrinology and metabolism, 94(11), 4205-4215. The Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 94, 11, pp. 4205-15
Journal of Clinical Endocrinology and Metabolism, 94, 4205-15
Journal of Clinical Endocrinology and Metabolism, 94(11), 4205-4215. ENDOCRINE SOC
de Lind van Wijngaarden, R F A, Siemensma, E P C, Festen, D A M, Otten, B J, van Mil, E G A H, Rotteveel, J, Odink, R J H, van Bindels-de Heus, G C B, Leeuwen, M, Haring, D A P J, Bocca, G, Houdijk, E C A M, Hoorweg-Nijman, J J G, Vreuls, R C F M, Jira, P E, Trotsenburg, A S P, Bakker, B, Schroor, E J, Pilon, J W, Wit, J M, Drop, S L S & Hokken-Koelega, A C S 2009, ' Efficacy and Safety of Long-Term Continuous Growth Hormone Treatment in Children with Prader-Willi Syndrome ', Journal of Clinical Endocrinology and Metabolism, vol. 94, no. 11, pp. 4205-4215 . https://doi.org/10.1210/jc.2009-0454
Journal of Clinical Endocrinology and Metabolism, 94(11), 4205-4215. The Endocrine Society
Contains fulltext : 80813.pdf (Publisher’s version ) (Closed access) BACKGROUND: Children with Prader-Willi syndrome (PWS) have abnormal body composition and impaired growth. Short-term GH treatment has beneficial effects. OBJECTIVES: The aim of th