Synthesis and evaluation of zirconium-89 labelled and long-lived GLP-1 receptor agonists for PET imaging.

Autor: Jacobsen CB; Global Research Technologies, Novo Nordisk A/S, Denmark; Isotope Chemistry, CMC Development, Novo Nordisk A/S, Denmark. Electronic address: cbjc@novonordisk.com., Raavé R; Department of Radiology and Nuclear Medicine, Radboudumc, Radboud Institute for Molecular Life Sciences, Nijmegen, the Netherlands., Pedersen MØ; Global Research Technologies, Novo Nordisk A/S, Denmark., Adumeau P; Institut de Chimie Moléculaire de l'Université de Bourgogne, UMR CNRS 6302, Université Bourgogne Franche-Comté, France., Moreau M; Institut de Chimie Moléculaire de l'Université de Bourgogne, UMR CNRS 6302, Université Bourgogne Franche-Comté, France., Valverde IE; Institut de Chimie Moléculaire de l'Université de Bourgogne, UMR CNRS 6302, Université Bourgogne Franche-Comté, France., Bjørnsdottir I; Global Drug Discovery, Novo Nordisk A/S, Denmark., Kristensen JB; Isotope Chemistry, CMC Development, Novo Nordisk A/S, Denmark., Grove MF; Global Drug Discovery, Novo Nordisk A/S, Denmark., Raun K; Global Drug Discovery, Novo Nordisk A/S, Denmark., McGuire J; Global Drug Discovery, Novo Nordisk A/S, Denmark., Goncalves V; Institut de Chimie Moléculaire de l'Université de Bourgogne, UMR CNRS 6302, Université Bourgogne Franche-Comté, France., Heskamp S; Department of Radiology and Nuclear Medicine, Radboudumc, Radboud Institute for Molecular Life Sciences, Nijmegen, the Netherlands., Denat F; Institut de Chimie Moléculaire de l'Université de Bourgogne, UMR CNRS 6302, Université Bourgogne Franche-Comté, France., Gustafsson M; Global Research Technologies, Novo Nordisk A/S, Denmark. Electronic address: mbfg@novonordisk.com.

Publikováno v: Nuclear medicine and biology [Nucl Med Biol] 2020 Mar - Apr; Vol. 82-83, pp. 49-56. Date of Electronic Publication: 2019 Dec 04.