Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Group-Specific Staining"'
Autor:
Masakazu Shimada, Koki Wada, Sachiyo Tanaka, Sawako Murakami, Nobuo Kanno, Kei Hayashi, Yasushi Hara
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
PLoS ONE, Vol 17, Iss 1, p e0262206 (2022)
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0262206 (2022)
PLoS ONE
This study aimed to determine the effects of long-term and high-dose administration of glucocorticoids (GCs) on the histological and mechanical properties of the cranial cruciate ligament (CrCL) in healthy beagle dogs. A synthetic corticosteroid at 2
Autor:
Dimitra Alexopoulou, Konstantinos Anastassiadis, Andreas Dahl, Julian Heuberger, Qinyu Zhang, Andrea Kranz, A. Francis Stewart, Walter Birchmeier, Neha Goveas, Kathrin Arndt, Claudia Waskow
Publikováno v:
PLoS Genetics, Vol 17, Iss 12, p e1009250 (2021)
PLoS Genet. 17:e1009250 (2021)
PLoS Genetics
PLoS Genet. 17:e1009250 (2021)
PLoS Genetics
Epigenetic mechanisms are gatekeepers for the gene expression patterns that establish and maintain cellular identity in mammalian development, stem cells and adult homeostasis. Amongst many epigenetic marks, methylation of histone 3 lysine 4 (H3K4) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8cb389560e0390b29db3df09769a3bc
http://edoc.mdc-berlin.de/21144/1/21144oa.pdf
http://edoc.mdc-berlin.de/21144/1/21144oa.pdf
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258495 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258495 (2021)
Modern histopathology is built on the cornerstone principle of tissue fixation, however there are currently no analytical methods of detecting fixation and as a result, in clinical practice fixation is highly variable and a persistent source of error
Autor:
Ming-En Hsu, Chien-Te Ho, Victor Chien-Chia Wu, Ying-Chang Tung, Winston W.-Y. Kao, Shao-Wei Chen, Pao-Hsien Chu, Fu-Chih Hsiao, Shing-Hsien Chou, Yi-Hsin Chan, An-Hsun Chou, Pyng-Jing Lin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0255238 (2021)
PLoS ONE, Vol 16, Iss 7, p e0255238 (2021)
Introduction Aortic dissection (AD) is a life-threatening emergency, and lumican (LUM) is a potential Biomarker for AD diagnosis. We investigated LUM expression patterns in patients with AD and explored the molecular functions of Lum in AD mice model
Autor:
Ryan W. Walters, Alyssa J. Block, Anthony E. Kincaid, Ronald A. Shikiya, Jason C. Bartz, Jiyan Ma, Thomas E. Eckland
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 7, p e1009765 (2021)
PLoS Pathogens, Vol 17, Iss 7, p e1009765 (2021)
Prions are comprised solely of PrPSc, the misfolded self-propagating conformation of the cellular protein, PrPC. Synthetic prions are generated in vitro from minimal components and cause bona fide prion disease in animals. It is unknown, however, if
Autor:
Pascal Hoffmann, Nadine Schnepel, Marion Langeheine, Katrin Künnemann, Guntram A Grassl, Ralph Brehm, Bettina Seeger, Gemma Mazzuoli-Weber, Gerhard Breves
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0256143 (2021)
PLoS ONE, Vol 16, Iss 8, p e0256143 (2021)
Gastrointestinal infectious diseases remain an important issue for human and animal health. Investigations on gastrointestinal infectious diseases are classically performed in laboratory animals leading to the problem that species-specific models are
Autor:
Daniel Ferguson, Niladri S. Kar, Joseph A. DiDonato, James T. Ryaby, Nianli Zhang, Erik I. Waldorff
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0247659 (2021)
PLoS ONE, Vol 16, Iss 2, p e0247659 (2021)
Pulsed-electromagnetic-field (PEMF) treatment was found to enhance cellular differentiation of the mouse preosteoblast, MC3T3-E1, to a more osteoblastic phenotype. Differentiation genes such as Alp, BSPI, cFos, Ibsp, Osteocalcin, Pthr1 and Runx2 show
Autor:
Hossam El-Din M. Omar, Gamal H. Abed, Mohammed E.M. Tolba, Faten A M Hassan, Sara S. Abdel-Hakeem
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11, p e0259847 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11, p e0259847 (2021)
Background Acanthamoeba spp. are one of the free-living amoeba that spread worldwide causing keratitis. Owing to the increase in the use of lenses, whether for medical or cosmetic purposes, the incidence of disease increases every year. Contamination
Autor:
Zhao Yang Chen, Kelly Y.P. Liu, Sarah Yuqi Zhu, Martial Guillaud, Alan Harrison, Catherine F. Poh
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0259529 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)
Background Early-stage oral squamous cell carcinoma (OSCC) patients have a one-in-four risk of regional metastasis (LN+), which is also the most significant prognostic factor for survival. As there are no validated biomarkers for predicting LN+ in ea
Autor:
Zhongmin Li, Goetz Muench, Hans-Peter Holthoff, Clara Wenhart, Julia Faßbender, Martin Ungerer
Publikováno v:
PLoS ONE, Vol 16, Iss 8 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0255363 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0255363 (2021)
The standard histological processing procedure, which produces excellent staining of sections for most tissues, fails to yield satisfactory results in adult mouse orbits or eyeballs. Here, we show that a protocol using tissue block staining and domes