Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Group I intron splicing"'
Publikováno v:
Biochemistry. 56:3571-3578
DEAD-box proteins are nonprocessive RNA helicases that play diverse roles in cellular processes. The Neurospora crassa DEAD-box protein CYT-19 promotes mitochondrial group I intron splicing and functions as a general RNA chaperone. CYT-19 includes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b85d2a4ff7218eb60365ac52c0ed52
https://doi.org/10.1021/acs.biochem.7b00362
https://doi.org/10.1021/acs.biochem.7b00362
Publikováno v:
BMC Molecular Biology, Vol 20, Iss 1, Pp 1-12 (2019)
BMC Molecular Biology
BMC Molecular Biology
Source at https://doi.org/10.1186/s12867-019-0134-y. Background - The mitochondrial genomes of mushroom corals (Corallimorpharia) are remarkable for harboring two complex group I introns; ND5-717 and COI-884. How these autocatalytic RNA elements inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0adb269e459574cdeb8ea20277dcc3
http://hdl.handle.net/11250/2608537
http://hdl.handle.net/11250/2608537
Autor:
Paul J. Paukstelis, Chun Geng
Publikováno v:
Biochemistry. 53:1311-1319
The mitochondrial tyrosyl tRNA synthetase from Neurospora crassa (CYT-18 protein) is a bifunctional group I intron splicing cofactor. CYT-18 is capable of splicing multiple group I introns from a wide variety of sources by stabilizing the catalytical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e37b00b7b2b92d4d763829340d63c4d
https://doi.org/10.1021/bi401614h
https://doi.org/10.1021/bi401614h
Publikováno v:
Journal of Biological Chemistry. 287:14772-14781
The yeast mitochondrial leucyl-tRNA synthetase (ymLeuRS) performs dual essential roles in group I intron splicing and protein synthesis. A specific LeuRS domain called CP1 is responsible for clearing noncognate amino acids that are misactivated durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0125622a1165d9ebce7ec98b3ba563
https://doi.org/10.1074/jbc.m111.322412
https://doi.org/10.1074/jbc.m111.322412
Autor:
Mark G. Caprara, Edward M. Turk
Publikováno v:
Journal of Biological Chemistry. 285:8585-8594
Yeast Suv3p is a member of the DEXH/D box family of RNA helicases and is a critical component of the mitochondrial degradosome, which also includes a 3' --5' exonuclease, Dss1p. Defects in the degradosome result in accumulation of aberrant transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46d2cbeda0ca5f9173a04d3f9287680
https://doi.org/10.1074/jbc.m109.090761
https://doi.org/10.1074/jbc.m109.090761
Autor:
Mark G. Caprara, Abby L. Bifano
Publikováno v:
Journal of Molecular Biology. 383:667-682
Proteins of the DExH/D family are ATPases that can unwind duplex RNA in vitro. Individual members of this family coordinate many steps in ribonucleoprotein enzyme assembly and catalysis in vivo, but it is largely unknown how the action of these co-fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f594569b2588b15ae11a9e68a958b07
https://doi.org/10.1016/j.jmb.2008.08.070
https://doi.org/10.1016/j.jmb.2008.08.070
Publikováno v:
Nucleic Acids Research
The Pet54p protein is an archetypical example of a dual functioning ('moonlighting') protein: it is required for translational activation of the COX3 mRNA and splicing of the aI5beta group I intron in the COX1 pre-mRNA in Saccharomyces cerevisiae mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e78ae68379dccdcac2542f3eef36072
https://doi.org/10.1093/nar/gkn045
https://doi.org/10.1093/nar/gkn045
Autor:
Scott A. Strobel, Mary R. Stahley
Publikováno v:
Current Opinion in Structural Biology. 16:319-326
The group I intron has served as a model for RNA catalysis since its discovery 25 years ago. Four recently determined high-resolution crystal structures complement extensive biochemical studies on this system. Structures of the Azoarcus, Tetrahymena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74e2f420ff203ebacfed58eb3a5873d
https://doi.org/10.1016/j.sbi.2006.04.005
https://doi.org/10.1016/j.sbi.2006.04.005
Autor:
Scott A. Strobel, Mary R. Stahley
Publikováno v:
Science. 309:1587-1590
We report the 3.4 angstrom crystal structure of a catalytically active group I intron splicing intermediate containing the complete intron, both exons, the scissile phosphate, and all of the functional groups implicated in catalytic metal ion coordin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a98dad812d966d24e5b02aa1d26c79b
https://doi.org/10.1126/science.1114994
https://doi.org/10.1126/science.1114994
Autor:
Mary R. Stahley, Michelle L. Gill, Scott A. Strobel, Anne B. Kosek, Peter L. Adams, Jimin Wang
Publikováno v:
RNA. 10:1867-1887
A recently reported crystal structure of an intact bacterial group I self-splicing intron in complex with both its exons provided the first molecular view into the mechanism of RNA splicing. This intron structure, which was trapped in the state prior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca551a63e4d9ac7e91e806a275cc1220
https://doi.org/10.1261/rna.7140504
https://doi.org/10.1261/rna.7140504