Zobrazeno 1 - 10 of 1 387 pro vyhledávání: '"Grossmann, U."'
1
Akademický článek
Nifurtimox for Treatment of Chagas Disease in Pediatric Patients: the Challenges of Applying Pharmacokinetic-Pharmacodynamic Principles to Dose Finding.
Autor: Stass H; Bayer AG, Clinical PK CV, Research & Development, Pharmaceuticals, Building 0431, Wuppertal, 42096, Germany. heino.stass@bayer.com., Ince I; Research & Development, Pharmaceuticals, Bayer AG, Building B106, Leverkusen, 51368, Germany., Grossmann U; Clinical Development & Operations, Bayer AG, Building P300, Müllerstrasse 178, Berlin, 13353, Germany., Weimann B; Chrestos Concept GmbH & Co. KG, Essen, Germany., Willmann S; Bayer AG, Clinical PK CV, Research & Development, Pharmaceuticals, Building 0431, Wuppertal, 42096, Germany.
Publikováno v: The AAPS journal [AAPS J] 2022 Aug 24; Vol. 24 (5), pp. 92. Date of Electronic Publication: 2022 Aug 24.
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2
Akademický článek
ELISA F29 -A therapeutic efficacy biomarker in Chagas disease: Evaluation in pediatric patients treated with nifurtimox and followed for 4 years post-treatment.
Autor: Rivero R; Instituto Nacional de Parasitología 'Dr Mario Fatala Chaben' ANLIS MALBRÁN, Ministerio de Salud, Buenos Aires, Argentina., Esteva MI; Instituto Nacional de Parasitología 'Dr Mario Fatala Chaben' ANLIS MALBRÁN, Ministerio de Salud, Buenos Aires, Argentina., Huang E; Bayer US LLC, Whippany, New Jersey, United States., Colmegna L; LAT Research, Buenos Aires, Argentina., Altcheh J; Hospital de Niños Ricardo Gutiérrez and Instituto Multidisciplinario de Investigación en Patologías Pediátricas (IMIPP), CONICET, Buenos Aires, Argentina.; CONICET, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina., Grossmann U; Bayer AG, Research and Development Pharmaceuticals, Berlin, Germany., Ruiz AM; Instituto Nacional de Parasitología 'Dr Mario Fatala Chaben' ANLIS MALBRÁN, Ministerio de Salud, Buenos Aires, Argentina.; CONICET, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.
Publikováno v: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Jun 23; Vol. 17 (6), pp. e0011440. Date of Electronic Publication: 2023 Jun 23 (Print Publication: 2023).
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3
Akademický článek
Efficacy and Safety of Nifurtimox in Pediatric Patients with Chagas Disease: Results at 4-Year Follow-Up in a Prospective, Historically Controlled Study (CHICO SECURE).
Autor: Altcheh J; Parasitología, Hospital de Niños Ricardo Gutiérrez and Instituto Multidisciplinario de Investigacion en Patologias Pediatricas (IMIPP), CONICET-GCBA, Buenos Aires, Argentina., Sierra V; Centro de Atención e Investigación Médica S.A., Yopal, Colombia., Ramirez T; Centro de Enfermedad de Chagas y Patologias Regionales, Santiago del Estero, Argentina., Pinto Rocha JJ; Fundación CEADES-Plataforma de Atención Integral a los Pacientes con Enfermedades de Chagas, Cochabamba, Bolivia., Grossmann U; Bayer AG, Research and Development Pharmaceuticals, Berlin, Germany., Huang E; Bayer US LLC, Whippany, New Jersey, USA., Moscatelli G; Parasitología, Hospital de Niños Ricardo Gutiérrez and Instituto Multidisciplinario de Investigacion en Patologias Pediatricas (IMIPP), CONICET-GCBA, Buenos Aires, Argentina., Ding O; Bayer HealthCare Co., Ltd., Shanghai, China.
Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2023 Apr 18; Vol. 67 (4), pp. e0119322. Date of Electronic Publication: 2023 Mar 28.
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4
Akademický článek
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5
Sheep models for cerebrovascular pathology
Autor: Nitzsche, B., Ferrara, F., Boltze, J., Hainsworth, A., Bridges, L., Deuther-Conrad, W., Dreyer, A., Gräßer, F., Großmann, U., Lobsien, D., Patt, M., Härtig, W., Sabri, O., Barthel, H.
Publikováno v: New animal models to understand the brain, 15.05.2017, Nouzilly, Frankreich
Worldwide, 5.5 M people die from stroke each year. Currently, stroke is still the third cause of death in industrialized countries and the leading cause of permanent disability in adulthood. About 78% of the incident stroke patients suffer from cereb
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::c786dd25d05835d792e354fe8fbaad0f
https://www.hzdr.de/publications/Publ-25513-1
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6
Akademický článek
Serological response to nifurtimox in adult patients with chronic Chagas disease: An observational comparative study in Argentina.
Autor: Vizcaya D; Bayer Pharmaceuticals, Sant Joan Despi, Spain., Grossmann U; Bayer AG, Berlin, Germany., Kleinjung F; Bayer AG, Berlin, Germany., Zhang R; Bayer HealthCare, Beijing, China., Suzart-Woischnik K; Bayer AG, Berlin, Germany., Seu S; Centro de Chagas y Patología Regional, Hospital Independencia, Santiago del Estero, Argentina., Ramirez T; Centro de Chagas y Patología Regional, Hospital Independencia, Santiago del Estero, Argentina., Colmegna L; LAT Research, Buenos Aires, Argentina., Ledesma O; Centro de Chagas y Patología Regional, Hospital Independencia, Santiago del Estero, Argentina.
Publikováno v: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Oct 04; Vol. 15 (10), pp. e0009801. Date of Electronic Publication: 2021 Oct 04 (Print Publication: 2021).
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8
Akademický článek
Circulating extracellular vesicles in sera of chronic patients as a method for determining active parasitism in Chagas disease.
Autor: Lozano, Noelia1,2 (AUTHOR), Prescilla-Ledezma, Alexa3,4 (AUTHOR), Calabuig, Eva5,6 (AUTHOR), Trelis, Maria1,7 (AUTHOR), Arce, José Miguel Sahuquillo2 (AUTHOR), López Hontangas, José Luis2 (AUTHOR), de Pablos, Luis Miguel4 (AUTHOR), Gomez-Samblas, Mercedes4 (AUTHOR), Osuna, Antonio4 (AUTHOR) aosuna@ugr.es
Publikováno v: PLoS Neglected Tropical Diseases. 11/20/2024, Vol. 18 Issue 11, p1-33. 33p.
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9
Akademický článek
Prospective, historically controlled study to evaluate the efficacy and safety of a new paediatric formulation of nifurtimox in children aged 0 to 17 years with Chagas disease one year after treatment (CHICO).
Autor: Altcheh J; Hospital de Niños Ricardo Gutiérrez and Instituto Multidisciplinario de Investigacion en Patologias Pediatricas (IMIPP), CONICET-GCBA, Buenos Aires, Argentina., Castro L; Centro de Atencion e Investigacion Medica S.A. (CAIMED-Yopal), Yopal, Colombia., Dib JC; Universidad del Norte, Barranquilla, Colombia., Grossmann U; Bayer AG, Research and Development Pharmaceuticals, Berlin, Germany., Huang E; Bayer US LLC, Whippany, New Jersey, United States of America., Moscatelli G; Hospital de Niños Ricardo Gutiérrez and Instituto Multidisciplinario de Investigacion en Patologias Pediatricas (IMIPP), CONICET-GCBA, Buenos Aires, Argentina., Pinto Rocha JJ; Fundación CEADES-Plataforma de Atención Integral a los Pacientes con Enfermedades de Chagas, Cochabamba, Bolivia., Ramírez TE; Centro de Enfermedad de Chagas y Patologias Regionales, Santiago del Estero, Argentina.
Publikováno v: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Jan 07; Vol. 15 (1), pp. e0008912. Date of Electronic Publication: 2021 Jan 07 (Print Publication: 2021).
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10
Double-labeling of stem cells for combined brain PET/MRI
Autor: Grossmann, U., Zeisig, V., Dreyer, A., Lobsien, D., Patt, M., Schildan, A., Boltze, J., Hoffmann, K., Sabri, O., Barthel, H.
Objectives: Stem cells (SCs) gain increasing interest as therapeutic option in a variety of brain and other disorders, like stroke. However, post-transplantation processes like SC homing into the infarcted brain tissue after stroke are not clearly un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______610::0cc1ac4e53a765a8ead78a28fede1ab5
https://publica.fraunhofer.de/handle/publica/259823
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