Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses

Autor: Rajamani, Uthra, Gross, Andrew R., Hjelm, Brooke E., Sequeira, Adolfo, Vawter, Marquis P., Tang, Jie, Gangalapudi, Vineela, Wang, Yizhou, Andres, Allen M., Gottlieb, Roberta A., Sareen, Dhruv

Publikováno v: In Cell Stem Cell 3 May 2018 22(5):698-712

Endocrine disruptors induce perturbations in endoplasmic reticulum and mitochondria of human pluripotent stem cell derivatives

Autor: Rajamani, Uthra, Gross, Andrew R., Ocampo, Camille, Andres, Allen M., Gottlieb, Roberta A., Sareen, Dhruv

Publikováno v: Nature Communications

Persistent exposure to man-made endocrine disrupting chemicals during fetal endocrine development may lead to disruption of metabolic homeostasis contributing to childhood obesity. Limited cellular platforms exist to test endocrine disrupting chemica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b85a09912473fd9dee13ef052203f170
https://pubmed.ncbi.nlm.nih.gov/30712056

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Retraction Note: Endocrine disruptors induce perturbations in endoplasmic reticulum and mitochondria of human pluripotent stem cell derivatives.

Autor: Rajamani, Uthra, Gross, Andrew R., Ocampo, Camille, Andres, Allen M., Gottlieb, Roberta A., Sareen, Dhruv

Publikováno v: Nature Communications; 2/2/2019, Vol. 10 Issue 1, p1-1, 1p

Hypothalamus and neuroendocrine diseases: The use of human-induced pluripotent stem cells for disease modeling.

Autor: de Souza Santos R; Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States; Cedars-Sinai Biomanufacturing Center, West Hollywood, CA, United States., Gross AR; Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States; Cedars-Sinai Biomanufacturing Center, West Hollywood, CA, United States., Sareen D; Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States; Cedars-Sinai Biomanufacturing Center, West Hollywood, CA, United States; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, United States; iPSC Core, David and Janet Polak Foundation Stem Cell Core Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA, United States. Electronic address: dhruv.sareen@cshs.org.

Publikováno v: Handbook of clinical neurology [Handb Clin Neurol] 2021; Vol. 181, pp. 337-350.