Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Groppe M"'
Publikováno v:
Clinical Ophthalmology, Vol Volume 15, Pp 651-659 (2021)
Markus Groppe,* Mandeep Singh Bindra* Retina Unit, Buckinghamshire Healthcare NHS Trust, Stoke Mandeville and Amersham Hospital, Aylesbury, HP21 8AL, UK*These authors contributed equally to this workCorrespondence: Markus GroppeRetina Unit, Buckingha
Externí odkaz:
https://doaj.org/article/f5e283b0b1784caa9bb08e9ea9aff40a
Publikováno v:
Clinical Ophthalmology, Vol Volume 14, Pp 2001-2009 (2020)
Laura J Wood,1,2,* Jasleen K Jolly,1,2,* Markus Groppe,3 Larry Benjamin,3 James F Kirwan,4 Nishal Patel,5 Mostafa A Elgohary,6 Robert E MacLaren1,2 1Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Ox
Externí odkaz:
https://doaj.org/article/368ad26409e14e3c8e863a82cc3bcf8d
Autor:
Amoaku W, Balaskas K, Cudrnak T, Downey L, Groppe M, Mahmood S, Mehta H, Mohamed Q, Mushtaq B, Severn P, Vardarinos A, Yang Y, Younis S
Publikováno v:
Clinical Ophthalmology, Vol Volume 12, Pp 1731-1740 (2018)
Winfried Amoaku,1 Konstantinos Balaskas,2,3 Tomas Cudrnak,4 Louise Downey,5 Markus Groppe,6 Sajjad Mahmood,7 Hemal Mehta,8 Quresh Mohamed,9 Bushra Mushtaq,10 Philip Severn,11 Athanasios Vardarinos,12 Yit Yang,13 Saad Younis14 1Academic Ophthalmology,
Externí odkaz:
https://doaj.org/article/54ecb5ae5ee04cb69e3504e3f24862e9
Publikováno v:
Eye. Apr2015, Vol. 29 Issue 4, p460-464. 5p.
Publikováno v:
Eye
Purpose Safe and reproducible delivery of gene therapy vector into the subretinal space is essential for successful targeting of the retinal pigment epithelium (RPE) and photoreceptors. The success of surgery is critical for the clinical efficacy of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::277d297d7cab75ed21315c518427ed4a
https://ora.ox.ac.uk/objects/uuid:4ed631f5-82bc-487f-9d35-e233201412db
https://ora.ox.ac.uk/objects/uuid:4ed631f5-82bc-487f-9d35-e233201412db
Genetic mutations are the cause of inherited retinal dystrophies. The underlying genetic basis of these diseases suggests that a gene therapy approach is logical either to replace or reduce the expression of defective genes. The first proof-of-concep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::411a4066fd3bc687c155a72c210d547e
https://doi.org/10.1007/s00347-011-2453-3
https://doi.org/10.1007/s00347-011-2453-3
Akademický článek
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Akademický článek
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Autor:
MacLaren, RE, Groppe, M, Barnard, AR, Cottriall, CL, Tolmachova, T, Seymour, L, Reed Clark, K, During, MJ, Cremers, FPM, Black, GCM, Lotery, AJ, Downes, SM, Webster, AR, Seabra, MC
Publikováno v:
The Lancet (London), 383, 9923, pp. 1129-37
Lancet
The Lancet (London), 383, 1129-37
Lancet
The Lancet (London), 383, 1129-37
Item does not contain fulltext BACKGROUND: Choroideremia is an X-linked recessive disease that leads to blindness due to mutations in the CHM gene, which encodes the Rab escort protein 1 (REP1). We assessed the effects of retinal gene therapy with an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b400ded0a620ddf6f52efe71105d5db
https://hdl.handle.net/2066/136730
https://hdl.handle.net/2066/136730