Zobrazeno 1 - 10
of 793
pro vyhledávání: '"Groothuis GMM"'
Autor:
Noh K; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario, M5S 3M2, Canada.; Drug Metabolism and Pharmacokinetics, Biogen, 225 Binney Street, Cambridge, Massachusetts, 02142, USA., Chow ECY; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario, M5S 3M2, Canada.; Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA., Quach HP; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario, M5S 3M2, Canada., Groothuis GMM; Pharmacokinetics, Toxicology and Targeting, Department of Pharmacy, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands., Tirona RG; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, N6A 5C1, Canada., Pang KS; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario, M5S 3M2, Canada. ks.pang@utoronto.ca.
Publikováno v:
The AAPS journal [AAPS J] 2022 Jun 01; Vol. 24 (4), pp. 71. Date of Electronic Publication: 2022 Jun 01.
Autor:
Suriguga S; The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China; Division of Pharmaceutical Technology and Biopharmacy, Department of Pharmacy, University of Groningen, Groningen, the Netherlands; Division of Pharmacokinetics, Toxicology and Targeting, Department of Pharmacy, University of Groningen, Groningen, the Netherlands., Luangmonkong T; Division of Pharmaceutical Technology and Biopharmacy, Department of Pharmacy, University of Groningen, Groningen, the Netherlands; Department of Pharmacology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand., Mutsaers HAM; Division of Pharmaceutical Technology and Biopharmacy, Department of Pharmacy, University of Groningen, Groningen, the Netherlands; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Groothuis GMM; Division of Pharmacokinetics, Toxicology and Targeting, Department of Pharmacy, University of Groningen, Groningen, the Netherlands., Olinga P; Division of Pharmaceutical Technology and Biopharmacy, Department of Pharmacy, University of Groningen, Groningen, the Netherlands. Electronic address: p.olinga@rug.nl.
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2020 Sep; Vol. 67, pp. 104920. Date of Electronic Publication: 2020 Jun 24.
Autor:
Han J; Groningen Research Institute of Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands. p.l.horvatovich@rug.nl., Sun J, Song S, Beljaars L, Groothuis GMM, Permentier H, Bischoff R, Halmos GB, Verhoeven CJ, Amstalden van Hove ER, Horvatovich P, Casini A
Publikováno v:
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Jun 04; Vol. 56 (44), pp. 5941-5944. Date of Electronic Publication: 2020 Apr 29.
Autor:
Liu, Qi1,2 (AUTHOR), Wang, Senyan1,2 (AUTHOR), Fu, Jing3 (AUTHOR), Chen, Yao3 (AUTHOR), Xu, Jing1 (AUTHOR), Wei, Wenjuan1 (AUTHOR), Song, Hao1 (AUTHOR), Zhao, Xiaofang1 (AUTHOR) zhaoxiaofang2099@163.com, Wang, Hongyang3 (AUTHOR) hywangk@vip.sina.com
Publikováno v:
Clinical & Translational Medicine. Aug2024, Vol. 14 Issue 8, p1-21. 21p.
Autor:
Estrada-Ortiz N; Dept. Pharmacokinetics , Toxicology and Targeting , Groningen Research Institute of Pharmacy , University of Groningen , A. Deusinglaan 1 , 9713AV Groningen , The Netherlands . Email: g.m.m.groothuis@rug.nl ; Email: angela.casini@tum.de., Lopez-Gonzales E; Dept. Pharmacokinetics , Toxicology and Targeting , Groningen Research Institute of Pharmacy , University of Groningen , A. Deusinglaan 1 , 9713AV Groningen , The Netherlands . Email: g.m.m.groothuis@rug.nl ; Email: angela.casini@tum.de., Woods B; School of Chemistry , Cardiff University , Main Building , Park Place , CF10 3AT Cardiff , UK., Stürup S; Dept. of Pharmacy , University of Copenhagen , Universitetsparken 2 , 2100 Copenhagen , Denmark., de Graaf IAM; Dept. Pharmacokinetics , Toxicology and Targeting , Groningen Research Institute of Pharmacy , University of Groningen , A. Deusinglaan 1 , 9713AV Groningen , The Netherlands . Email: g.m.m.groothuis@rug.nl ; Email: angela.casini@tum.de., Groothuis GMM; Dept. Pharmacokinetics , Toxicology and Targeting , Groningen Research Institute of Pharmacy , University of Groningen , A. Deusinglaan 1 , 9713AV Groningen , The Netherlands . Email: g.m.m.groothuis@rug.nl ; Email: angela.casini@tum.de., Casini A; Dept. Pharmacokinetics , Toxicology and Targeting , Groningen Research Institute of Pharmacy , University of Groningen , A. Deusinglaan 1 , 9713AV Groningen , The Netherlands . Email: g.m.m.groothuis@rug.nl ; Email: angela.casini@tum.de.; School of Chemistry , Cardiff University , Main Building , Park Place , CF10 3AT Cardiff , UK.; Department of Chemistry , Technical University of Munich , Lichtenbergstr. 4 , 85748 Garching b. München , Germany.
Publikováno v:
Toxicology research [Toxicol Res (Camb)] 2019 Sep 20; Vol. 8 (6), pp. 885-895. Date of Electronic Publication: 2019 Sep 20 (Print Publication: 2019).
Autor:
Guzmán-Delgado NE; División de Investigación en Salud, UMAE, Hospital de Cardiología #34, Instituto Mexicano del Seguro Social, Monterrey, Nuevo León, Mexico., Carranza-Torres IE; Centro de Investigación Biomédica del Noreste, Instituto Mexicano del Seguro Social, Monterrey, Nuevo León, Mexico.; Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Nuevo León, Mexico., García-Davis S; Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Nuevo León, Mexico., Rivera G; Laboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa, 88710, Tamaulipas, Mexico., Morán-Martínez J; Centro de Investigación Biomédica, Facultad de Medicina, Universidad Autónoma de Coahuila, Torreón, Coahuila, Mexico., Betancourt-Martínez ND; Centro de Investigación Biomédica, Facultad de Medicina, Universidad Autónoma de Coahuila, Torreón, Coahuila, Mexico., Groothuis GMM; Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands., de Graaf IAM; Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands., Carranza-Rosales P; Centro de Investigación Biomédica del Noreste, Instituto Mexicano del Seguro Social, Monterrey, Nuevo León, Mexico. carranza60@yahoo.com.mx.
Publikováno v:
Scientific reports [Sci Rep] 2019 Jun 10; Vol. 9 (1), pp. 8396. Date of Electronic Publication: 2019 Jun 10.
Autor:
Kumar D; Department of Mechanical Engineering, Indian Institute of Technology Ropar, Punjab, 140001, India., Nadda R; Department of Biomedical Engineering, Indian Institute of Technology Ropar, Punjab, 140001, India. rahulnadda74@gmail.com., Repaka R; Department of Mechanical Engineering, Indian Institute of Technology Ropar, Punjab, 140001, India.; Department of Biomedical Engineering, Indian Institute of Technology Ropar, Punjab, 140001, India.
Publikováno v:
Medical & biological engineering & computing [Med Biol Eng Comput] 2024 Jul; Vol. 62 (7), pp. 1925-1957. Date of Electronic Publication: 2024 Mar 04.
Publikováno v:
Drug Metabolism and Disposition, 29(4), 361-367. AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS
We developed and tested a novel method for perfusing parts of human liver to study uptake and handling of drug-targeting preparations. These preparations, designed for the treatment of liver fibrosis in man, have been extensively studied in animals,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::cac5731d6f7d178bed3e1f7e3c82277a
https://research.rug.nl/en/publications/0c73791c-5084-410b-b686-22e645315e06
https://research.rug.nl/en/publications/0c73791c-5084-410b-b686-22e645315e06
Autor:
Olinga, P, Hof, IH, Smit, M, de Jager, MH, Swart, PJ, Slooff, MJH, Meijer, DKF, Groothuis, GMM, Merema, M.T.
Publikováno v:
Journal of Pharmacological and Toxicological Methods, 45(1), 55-63
In the present study we investigated the applicability of the liver slice model to study mechanisms of drug uptake. Four model compounds were investigated that enter hepatocytes via entirely different membrane transport mechanisms. Rhodamine B (RB),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::dc7560045ec96c12ecc4ac89d72e0b6b
https://research.rug.nl/en/publications/a0d631ab-1b09-4573-a3cb-054934919e61
https://research.rug.nl/en/publications/a0d631ab-1b09-4573-a3cb-054934919e61
Publikováno v:
Liver, 20(5), 374-380
Aims/Background: In liver transplantation, adequate function tests for donor livers and transplanted livers are of utmost importance to provide an objective basis for decision-making. Isolated hepatocyte and/or slice preparations from human donor liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::732f3b4a3745a4685f04e8cc59b958bf
https://research.rug.nl/en/publications/dfd08fdf-79e4-482b-81d8-40e4b7cd5f6e
https://research.rug.nl/en/publications/dfd08fdf-79e4-482b-81d8-40e4b7cd5f6e