CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma.

Autor: Houles T; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada., Lavoie G; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada., Nourreddine S; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada.; Department of Bioengineering, University of California, San Diego, San Diego, CA, USA., Cheung W; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada., Vaillancourt-Jean É; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada., Guérin CM; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada., Bouttier M; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada., Grondin B; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada.; Department of Biological Sciences, Université du Québec à Montréal, Montreal, QC, Canada., Lin S; Donnelly Centre for Cellular & Biomolecular Research, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Saba-El-Leil MK; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada., Angers S; Donnelly Centre for Cellular & Biomolecular Research, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.; Department of Biochemistry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Meloche S; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada.; Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada., Roux PP; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, 2950, Chemin de la Polytechnique, Montréal, QC, H3T 1J4, Canada. philippe.roux@umontreal.ca.; Department of Pathology and Cell Biology, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada. philippe.roux@umontreal.ca.

Publikováno v: Nature communications [Nat Commun] 2022 Oct 29; Vol. 13 (1), pp. 6457. Date of Electronic Publication: 2022 Oct 29.

Otx1 enhances erythroid differentiation through activation of the SCL gene

Autor: Sincennes MC., Sanguin-Gendreau V., Martin R., Grondin B., Tremblay M., Cerisoli F., Magli M.C., Hoang T.

Publikováno v: 47th ASH Meeting, Atlanta, 2005
info:cnr-pdr/source/autori:Sincennes MC., Sanguin-Gendreau V., Martin R., Grondin B., Tremblay M., Cerisoli F., Magli M.C. & Hoang T./congresso_nome: 47th ASH Meeting/congresso_luogo: Atlanta/congresso_data:2005/anno:2005/pagina_da:/pagina_a:/intervallo_pagine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::b4cf7e300adcf45a74c90b62191b8ea7
http://www.cnr.it/prodotto/i/129268

RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma.

Autor: Houles T; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, Quebec, Canada., Gravel SP; Department of Biochemistry, Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada., Lavoie G; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, Quebec, Canada., Shin S; Department of Cancer Biology & Pharmacology, University of Illinois College of Medicine, Peoria, Illinois., Savall M; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, Quebec, Canada., Méant A; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, Quebec, Canada., Grondin B; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, Quebec, Canada., Gaboury L; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, Quebec, Canada.; Department of Pathology and Cell Biology, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Yoon SO; Department of Cancer Biology & Pharmacology, University of Illinois College of Medicine, Peoria, Illinois., St-Pierre J; Department of Biochemistry, Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada., Roux PP; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, Quebec, Canada. philippe.roux@umontreal.ca.; Department of Pathology and Cell Biology, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.

Publikováno v: Cancer research [Cancer Res] 2018 May 01; Vol. 78 (9), pp. 2191-2204. Date of Electronic Publication: 2018 Feb 12.

Recent Advances in Therapeutic Strategies to Improve Colorectal Cancer Treatment.

Autor: Gmeiner, William H.¹ (AUTHOR) bgmeiner@wakehealth.edu

Publikováno v: Cancers. Mar2024, Vol. 16 Issue 5, p1029. 19p.

Transcriptomic analysis identifies B-lymphocyte kinase as a therapeutic target for desmoplastic small round cell tumor cancer stem cell-like cells.

Autor: Magrath, Justin W.¹ (AUTHOR), Flinchum, Dane A.¹ (AUTHOR), Hartono, Alifiani B.^1,2 (AUTHOR), Sampath, Shruthi Sanjitha¹ (AUTHOR), O'Grady, Tina M.¹ (AUTHOR), Baddoo, Melody¹ (AUTHOR), Haoyang, Liang¹ (AUTHOR), Xu, Xiaojiang¹ (AUTHOR), Flemington, Erik K.¹ (AUTHOR), Lee, Sean B.¹ (AUTHOR) slee30@tulane.edu

Publikováno v: Oncogenesis. 1/4/2024, Vol. 13 Issue 1, p1-15. 15p.