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Preclinical evaluation of BAY 1075553, a novel ¹⁸F-labelled inhibitor of prostate-specific membrane antigen for PET imaging of prostate cancer.

Autor: Lesche, Ralf, Kettschau, Georg, Gromov, Alexey V., Böhnke, Niels, Borkowski, Sandra, Mönning, Ursula, Hegele-Hartung, Christa, Döhr, Olaf, Dinkelborg, Ludger M., Graham, Keith

Publikováno v: European Journal of Nuclear Medicine & Molecular Imaging; Jan2014, Vol. 41 Issue 1, p89-101, 13p

β-Arylthio-α-chloroalkyl Ethers — Novel 1,1-Bis-electrophiles for Geminal Alkylation

Autor: Gromov, Alexey V., Smit, William A.

Publikováno v: European Journal of Organic Chemistry; March 2006, Vol. 2006 Issue: 5 p1317-1322, 6p

New Generation of sGC Stimulators: Discovery of Imidazo[1,2- a ]pyridine Carboxamide BAY 1165747 (BAY-747), a Long-Acting Soluble Guanylate Cyclase Stimulator for the Treatment of Resistant Hypertension.

Autor: Vakalopoulos A; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Wunder F; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Hartung IV; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Redlich G; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Jautelat R; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Buchgraber P; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Hassfeld J; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Gromov AV; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Lindner N; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Bierer D; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Gries J; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Kroh W; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Paulsen H; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Mittendorf J; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Lang D; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Becker-Pelster E; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Brockschnieder D; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Geiss V; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Li V; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Straub A; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Knorr A; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Mondritzki T; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany.; University of Witten/Herdecke, 58455 Witten, Germany., Trübel H; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany.; University of Witten/Herdecke, 58455 Witten, Germany., Raschke M; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Schaefer M; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany.; Lead Discovery, Nuvisan ICB GmbH, Muellerstrasse 178, 13353 Berlin, Germany., Thomas D; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany., Sandner P; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany.; Department of Pharmacology, Hannover Medical School, 30625 Hannover, Germany., Stasch JP; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany.; Institute of Pharmacy, Martin Luther University, 06120 Halle, Germany., Follmann M; Pharmaceuticals, Research and Development, Bayer AG, Aprather Weg 18a, 42113 Wuppertal, Germany.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2023 Jun 08; Vol. 66 (11), pp. 7280-7303. Date of Electronic Publication: 2023 Apr 11.