Encapsulation of a TRPM8 Agonist, WS12, in Lipid Nanocapsules Potentiates PC3 Prostate Cancer Cell Migration Inhibition through Channel Activation

Autor: Grolez, G., Hammadi, M., Barras, Alexandre, Gordienko, D., Slomianny, C., Völkel, P., Angrand, P., Pinault, M., Guimaraes, C., Potier-Cartereau, M., Prevarskaya, N., Boukherroub, Rabah, Gkika, D.

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-44452-4⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-44452-4⟩

International audience; In prostate carcinogenesis, expression and/or activation of the Transient Receptor Potential Melastatin 8 channel (TRPM8) was shown to block in vitro Prostate Cancer (PCa) cell migration. Because of their localization at the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::df0c33559418ff911458c53c5d619a50
https://hal.archives-ouvertes.fr/hal-02373190

The value of magnetic resonance imaging as a biomarker for amyotrophic lateral sclerosis: a systematic review.

Autor: Grolez, G.^1,2, Moreau, C.^1,2, Danel-Brunaud, V.^1,2, Delmaire, C.², Lopes, R.², Pradat, P. F., El Mendili, M. M., Defebvre, L.^1,2, Devos, D.^1,2 david.devos@chru-lille.fr

Publikováno v: BMC Neurology. 8/27/2016, Vol. 16, p1-17. 17p. 3 Charts.

Could Conservative Iron Chelation Lead to Neuroprotection in Amyotrophic Lateral Sclerosis?

Autor: Moreau, C, Danel, V, Devedjian, JC, Grolez, G, Timmerman, K, Laloux, C, Petrault, M, Gouel, F, Jonneaux, A, Dutheil, M, Lachaud, C, Lopes, R, Kuchinski, G, Auger, F, Kyheng, M, Duhamel, A, Pérez, T, Pradat, P-F, Blasco, H, Veyrat-Durebex, C, Corcia, P, Oeckl, P, Otto, M, Dupuis, L, Garçon, G, Defebvre, L, Cabantchik, IZ, Duce, J, Bordet, R, Devos, D

Publikováno v: Antioxidants & Redox Signaling
Antioxidants & Redox Signaling, 2018, 29, pp.742-748. ⟨10.1089/ars.2017.7493⟩

International audience; Iron accumulation has been observed in mouse models and in both sporadic and familial forms of amyotrophic lateral sclerosis (ALS). Iron chelation could reduce iron accumulation and the related excess of oxidative stress in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a66c5f9dac8204ba7d8415d2100b35a3
https://hal.univ-angers.fr/hal-02616908/document

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Small Molecules, α-Synuclein Pathology, and the Search for Effective Treatments in Parkinson's Disease.

Autor: Sechi, Gian Pietro¹ (AUTHOR) gpsechi@uniss.it, Sechi, M. Margherita¹ (AUTHOR)

Publikováno v: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 20, p11198. 17p.