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Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data.
Autor:
Schäfer A; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland., Gjerga E; Faculty of Medicine, Joint Research Centre for Computational Biomedicine (JRC-COMBINE), RWTH Aachen University, Aachen, Germany., Welford RW; Idorsia Pharmaceuticals, Allschwil, Switzerland., Renz I; Idorsia Pharmaceuticals, Allschwil, Switzerland., Lehembre F; Idorsia Pharmaceuticals, Allschwil, Switzerland., Groenen PM; Idorsia Pharmaceuticals, Allschwil, Switzerland., Saez-Rodriguez J; Faculty of Medicine, Joint Research Centre for Computational Biomedicine (JRC-COMBINE), RWTH Aachen University, Aachen, Germany.; Faculty of Medicine, Institute for Computational Biomedicine, Heidelberg University Hospital, Bioquant, Heidelberg University, Heidelberg, Germany., Aebersold R; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.; Faculty of Science, University of Zürich, Zürich, Switzerland., Gstaiger M; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.; Competence Center Personalized Medicine UZH/ETH, Zürich, Switzerland.
Publikováno v:
Molecular systems biology [Mol Syst Biol] 2019 Aug; Vol. 15 (8), pp. e8828.
Autor:
Stalder AK; Translational Science, Drug Discovery Biology, Actelion Pharmaceuticals Ltd, 4123, Allschwil, Switzerland., Lott D; Clinical Pharmacology, Actelion Pharmaceuticals Ltd, 4123, Allschwil, Switzerland., Strasser DS; Translational Science, Drug Discovery Biology, Actelion Pharmaceuticals Ltd, 4123, Allschwil, Switzerland., Cruz HG; Clinical Pharmacology, Actelion Pharmaceuticals Ltd, 4123, Allschwil, Switzerland., Krause A; Clinical Pharmacology, Actelion Pharmaceuticals Ltd, 4123, Allschwil, Switzerland., Groenen PM; Translational Science, Drug Discovery Biology, Actelion Pharmaceuticals Ltd, 4123, Allschwil, Switzerland., Dingemanse J; Clinical Pharmacology, Actelion Pharmaceuticals Ltd, 4123, Allschwil, Switzerland.
Publikováno v:
British journal of clinical pharmacology [Br J Clin Pharmacol] 2017 Mar; Vol. 83 (3), pp. 476-486. Date of Electronic Publication: 2016 Nov 15.
Autor:
Agache I; Transylvania University Brasov, Brasov, Romania., Strasser DS; Department of Translational Science, Actelion Pharmaceuticals Ltd., Davos, Switzerland., Klenk A; Information Management Drug Discovery, Actelion Pharmaceuticals Ltd., Davos, Switzerland., Agache C; Theramed Medical Center, Brasov, Romania.; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Davos, Switzerland., Farine H; Department of Translational Science, Actelion Pharmaceuticals Ltd., Davos, Switzerland., Ciobanu C; Theramed Medical Center, Brasov, Romania., Groenen PM; Department of Translational Science, Actelion Pharmaceuticals Ltd., Davos, Switzerland., Akdis CA; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Davos, Switzerland.; Swiss Institute for Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
Publikováno v:
Allergy [Allergy] 2016 Aug; Vol. 71 (8), pp. 1192-202. Date of Electronic Publication: 2016 Apr 29.
Autor:
Welford RW; Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland., Vercauteren M; Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland., Trébaul A; Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland., Cattaneo C; Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland., Eckert D; Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland., Garzotti M; Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland., Sieber P; Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland., Segrestaa J; Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland., Studer R; Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland., Groenen PM; Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland., Nayler O; Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland.
Publikováno v:
Scientific reports [Sci Rep] 2016 Jul 21; Vol. 6, pp. 30059. Date of Electronic Publication: 2016 Jul 21.
Autor:
Géhin M; Department of Clinical Pharmacology, Actelion Pharmaceuticals Ltd, Allschwil, Switzerland., Strasser DS; Department of Translational Science, Actelion Pharmaceuticals Ltd, Allschwil, Switzerland., Zisowsky J; Department of Clinical Pharmacology, Actelion Pharmaceuticals Ltd, Allschwil, Switzerland., Farine H; Department of Translational Science, Actelion Pharmaceuticals Ltd, Allschwil, Switzerland., Groenen PM; Department of Translational Science, Actelion Pharmaceuticals Ltd, Allschwil, Switzerland., Dingemanse J; Department of Clinical Pharmacology, Actelion Pharmaceuticals Ltd, Allschwil, Switzerland., Sidharta PN; Department of Clinical Pharmacology, Actelion Pharmaceuticals Ltd, Allschwil, Switzerland.
Publikováno v:
Journal of clinical pharmacology [J Clin Pharmacol] 2015 Jul; Vol. 55 (7), pp. 787-97. Date of Electronic Publication: 2015 Mar 30.
Autor:
Groenen PM; MSD, Merck Research Laboratories, Molecular Design & Informatics, PO Box 20, 5340BH Oss, The Netherlands. pma.groenen@gmail.com
Publikováno v:
Pharmacogenomics [Pharmacogenomics] 2011 Sep; Vol. 12 (9), pp. 1249-52.
Autor:
Hulsen T; Computational Drug Discovery, CMBI, NCMLS, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands. t.hulsen@cmbi.ru.nl, Groenen PM, de Vlieg J, Alkema W
Publikováno v:
Nucleic acids research [Nucleic Acids Res] 2009 Jan; Vol. 37 (Database issue), pp. D731-7. Date of Electronic Publication: 2008 Oct 02.
Autor:
Hulsen T; Centre for Molecular and Biomolecular Informatics, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. T.Hulsen@cmbi.ru.nl, de Vlieg J, Leunissen JA, Groenen PM
Publikováno v:
BMC bioinformatics [BMC Bioinformatics] 2006 Oct 12; Vol. 7, pp. 444. Date of Electronic Publication: 2006 Oct 12.
Autor:
Hulsen T; Centre for Molecular and Biomolecular Informatics (CMBI), Nijmegen Centre for Molecular Life Sciences (NCMLS), Radboud University Nijmegen, Nijmegen, The Netherlands. T.Hulsen@cmbi.ru.nl, de Vlieg J, Groenen PM
Publikováno v:
BMC bioinformatics [BMC Bioinformatics] 2006 Sep 01; Vol. 7, pp. 398. Date of Electronic Publication: 2006 Sep 01.