Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Groendyke Todd Michael"'
Autor:
Fredrik Pehr Marmsater, Jeffrey M. Schkeryantz, Dana Rae Benesh, Maria-Jesus Blanco, Amy Clemens-Smith, Renee Emkey, Kirk W. Johnson, Michael P. Johnson, Fese Mokube, Groendyke Todd Michael, James Allen Knobelsdorf, Tony Pisal Tang, Mark A. Muhlhauser, Cortez Guillermo S, Thomas Daniel Aicher, Albert Khilevich, Steven Swanson, John T. Catlow
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(2)
Pyridylmethylsulfonamide series were the first reported example of positive allosteric modulators (PAM) of the mGlu2 receptor. The hydroxyacetophenone scaffold is a second series of mGlu2 PAMs we have identified. This series of molecules are potent m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5d8e11f4b6d50d127416a2d5c6aa8c
https://pubmed.ncbi.nlm.nih.gov/27908761
https://pubmed.ncbi.nlm.nih.gov/27908761
Autor:
Gary D. Glick, Thomas B. Sundberg, Tasha M. Francis, Joanne Cleary, Anthony W. Opipari, Groendyke Todd Michael
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:2423-2427
A family of 1,4-benzodiazepine-2,5-diones (BZDs) has been synthesized and evaluated against transformed B- and T-cells for lymphotoxic members. A large aromatic group on the C3 position is critical for cytotoxicity. When the C3 moiety contains an ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67067aeb5ce317dc95e35300c27eccb3
https://doi.org/10.1016/j.bmcl.2006.01.113
https://doi.org/10.1016/j.bmcl.2006.01.113
Publikováno v:
Journal of the American Chemical Society. 128(14)
Allylic phosphonium ylides are readily generated by the combination of an allylic alcohol, a carbene, and a chlorophosphite. Here we demonstrate that these intermediates undergo a thermal [3,3]-rearrangement to provide single isomers of homoallylic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac2108040038172acab469895b81f79
https://pubmed.ncbi.nlm.nih.gov/16594686
https://pubmed.ncbi.nlm.nih.gov/16594686