Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

Autor: Demontis, D, Walters, R, Martin, J, Mattheisen, M, Als, T, Agerbo, E, Baldursson, G, Belliveau, R, Bybjerg-Grauholm, J, Baekvad-Hansen, M, Cerrato, F, Chambert, K, Churchhouse, C, Dumont, A, Eriksson, N, Gandal, M, Goldstein, J, Grasby, K, Grove, J, Gudmundsson, O, Hansen, C, Hauberg, M, Hollegaard, M, Howrigan, D, Huang, H, Maller, J, Martin, A, Martin, N, Moran, J, Pallesen, J, Palmer, D, Pedersen, C, Pedersen, M, Poterba, T, Poulsen, J, Ripke, S, Robinson, E, Satterstrom, F, Stefansson, H, Stevens, C, Turley, P, Walters, G, Won, H, Wright, M, Andreassen, O, Asherson, P, Burton, C, Boomsma, D, Cormand, B, Dalsgaard, S, Franke, B, Gelernter, J, Geschwind, D, Hakonarson, H, Haavik, J, Kranzler, H, Kuntsi, J, Langley, K, Lesch, K, Middeldorp, C, Reif, A, Rohde, L, Roussos, P, Schachar, R, Sklar, P, Sonuga-Barke, E, Sullivan, P, Thapar, A, Tung, J, Waldman, I, Medland, S, Stefansson, K, Nordentoft, M, Hougaard, D, Werge, T, Mors, O, Mortensen, P, Daly, M, Faraone, S, Borglum, A, Neale, B, Albayrak, O, Anney, R, Arranz, M, Banaschewski, T, Bau, C, Biederman, J, Buitelaar, J, Casas, M, Charach, A, Crosbie, J, Dempfle, A, Doyle, A, Ebstein, R, Elia, J, Freitag, C, Focker, M, Gill, M, Grevet, E, Hawi, Z, Hebebrand, J, Herpertz-Dahlmann, B, Hervas, A, Hinney, A, Hohmann, S, Holmans, P, Hutz, M, Ickowitz, A, Johansson, S, Kent, L, Kittel-Schneider, S, Lambregts-Rommelse, N, Lehmkuhl, G, Loo, S, McGough, J, Meyer, J, Mick, E, Middletion, F, Miranda, A, Mota, N, Mulas, F, Mulligan, A, Nelson, F, Nguyen, T, Oades, R, O'Donovan, M, Owen, M, Palmason, H, Ramos-Quiroga, J, Renner, T, Ribases, M, Rietschel, M, Rivero, O, Romanos, J, Romanos, M, Rothenberger, A, Royers, H, Sanchez-Mora, C, Scherag, A, Schimmelmann, B, Schafer, H, Sergeant, J, Sinzig, J, Smalley, S, Steinhausen, H, Thompson, M, Todorov, A, Vasquez, A, Walitza, S, Wang, Y, Warnke, A, Williams, N, Witt, S, Yang, L, Zayats, T, Zhang-James, Y, Smith, G, Davies, G, Ehli, E, Evans, D, Fedko, I, Greven, C, Groen-Blokhuis, M, Guxens, M, Hammerschlag, A, Hartman, C, Heinrich, J, Hottenga, J, Hudziak, J, Jugessur, A, Kemp, J, Krapohl, E, Murcia, M, Myhre, R, Nolte, I, Nyholt, D, Ormel, J, Ouwens, K, Pappa, I, Pennell, C, Plomin, R, Ring, S, Standl, M, Stergiakouli, E, St Pourcain, B, Stoltenberg, C, Sunyer, J, Thiering, E, Tiemeier, H, Tiesler, C, Timpson, N, Trzaskowski, M, van der Most, P, Vilor-Tejedor, N, Wang, C, Whitehouse, A, Zhao, H, Agee, M, Alipanahi, B, Auton, A, Bell, R, Bryc, K, Elson, S, Fontanillas, P, Furlotte, N, Hinds, D, Hromatka, B, Huber, K, Kleinman, A, Litterman, N, McIntyre, M, Mountain, J, Northover, C, Pitts, S, Sathirapongsasuti, J, Sazonova, O, Shelton, J, Shringarpure, S, Tian, C, Vacic, V, Wilson, C, ADHD Working Grp Psychiat Genomics, Early Lifecourse Genetic, 23andMe Res Team

Publikováno v: Demontis, D, Walters, R K, Martin, J, Mattheisen, M, Als, T D, Agerbo, E, Baldursson, G, Belliveau, R, Bybjerg-Grauholm, J, Bækvad-Hansen, M, Cerrato, F, Chambert, K, Churchhouse, C, Dumont, A, Eriksson, N, Gandal, M, Goldstein, J I, Grasby, K L, Grove, J, Gudmundsson, O O, Hansen, C S, Hauberg, M E, Hollegaard, M V, Howrigan, D P, Huang, H, Maller, J B, Martin, A R, Moran, J, Martin, N G, Pallesen, J, Palmer, D S, Pedersen, C B, Pedersen, M G, Poterba, T, Poulsen, J B, Ripke, S, Robinson, E B, Satterstrom, F K, Stefansson, H, Stevens, C, Turley, P, Walters, G B, Won, H, Wright, M J, ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Steinhausen, H-C E, Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium, 23andMe Research Team, Andreassen, O A, Asherson, P, Burton, C L, Boomsma, D I, Cormand, B, Dalsgaard, S, Franke, B, Gelernter, J, Geschwind, D, Hakonarson, H, Haavik, J, Kranzler, H R, Kuntsi, J, Langley, K, Lesch, K-P, Middeldorp, C, Reif, A, Rohde, L A, Roussos, P, Schachar, R, Sklar, P, Sonuga-Barke, E J S, Sullivan, P F, Thapar, A, Tung, J Y, Waldman, I D, Medland, S E, Stefansson, K, Nordentoft, M, Hougaard, D M, Werge, T, Mors, O, Mortensen, P B, Daly, M J, Faraone, S V, Børglum, A D & Neale, B M 2019, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ', Nature Genetics, vol. 51, no. 1, pp. 63-75 . https://doi.org/10.1038/s41588-018-0269-7
NATURE GENETICS
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Nature genetics, vol 51, iss 1
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
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r-FISABIO. Repositorio Institucional de Producción Científica
Nature Genetics
23andMe Research Team, ADHD Working Group of the Psychiatric Genomics Consortium (PGC) & Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium 2019, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ', Nature Genetics, vol. 51, no. 1, pp. 63-75 . https://doi.org/10.1038/s41588-018-0269-7, https://doi.org/10.1038/s41588-018-0269-7
Nature Genetics, 51(1), 63-75. Nature Publishing Group
Demontis, D, Walters, R K, Martin, J, Mattheisen, M, Als, T D, Agerbo, E, Baldursson, G S, Belliveau, R, Bybjerg-Grauholm, J, Bækvad-Hansen, M, Cerrato, F, Chambert, K, Churchhouse, C, Dumont, A, Eriksson, N, Gandal, M, Goldstein, J I, Grasby, K L, Grove, J, Gudmundsson, O O, Hansen, C S, Hauberg, M E, Hollegaard, M V, Howrigan, D P, Huang, H, Maller, J B, Martin, A R, Martin, N G, Moran, J, Pallesen, J, Palmer, D S, Pedersen, C B C, Pedersen, M G, Poterba, T, Poulsen, J B, Ripke, S, Robinson, E B, Satterstrom, F K, Stefansson, H, Stevens, C, Turley, P, Walters, G B, Won, H, Wright, M J, Albayrak, Ö, Nguyen, T T, Evans, D M, Groen-Blokhuis, M M, Hammerschlag, A R, Middeldorp, C, ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Reif, A, Rohde, L A, Roussos, P, Schachar, R, Sonuga-Barke, E J S, Sullivan, P, Thapar, A, Tung, J Y, Waldman, I D, Medland, S E, Mors, O, Bo Mortensen, P, Daly, M J, Faraone, S V, Børglum, A D & Neale, B M 2019, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ', Nature Genetics, vol. 51, no. 1, pp. 63-75 . https://doi.org/10.1038/s41588-018-0269-7
ADHD Working Group of the Psychiatric Genomics Consortium (PGC) 2018, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ' Nature Genetics . https://doi.org/10.1038/s41588-018-0269-7
Nature Genetics, 51, 1, pp. 63-75
Demontis, D, Walters, R K, Martin, J, Mattheisen, M, Als, T D, Agerbo, E, Baldursson, G, Belliveau, R, Bybjerg-Grauholm, J, Bækvad-Hansen, M, Cerrato, F, Chambert, K, Churchhouse, C, Dumont, A, Eriksson, N, Gandal, M, Goldstein, J I, Grasby, K L, Grove, J, Gudmundsson, O O, Hansen, C S, Hauberg, M E, Hollegaard, M V, Howrigan, D P, Huang, H, Maller, J B, Martin, A R, Martin, N G, Moran, J, Pallesen, J, Palmer, D S, Pedersen, C B, Pedersen, M G, Poterba, T, Poulsen, J B, Ripke, S, Robinson, E B, Satterstrom, F K, Stefansson, H, Stevens, C, Turley, P, Walters, G B, Won, H, Wright, M J, ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium, 23andMe Research Team, Dalsgaard, S, Mors, O, Mortensen, P B & Børglum, A D 2019, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ', Nature Genetics, vol. 51, pp. 63–75 . https://doi.org/10.1038/s41588-018-0269-7
Nat Genet
Nature Genetics, 51, 63-75
Nature Genetics, 51(1), 63-+. Nature Publishing Group
Demontis, D, Walters, R K, Martin, J, Mattheisen, M, Als, T D, Agerbo, E, Baldursson, G, Belliveau, R, Bybjerg-grauholm, J, Bækvad-hansen, M, Cerrato, F, Chambert, K, Churchhouse, C, Dumont, A, Eriksson, N, Gandal, M, Goldstein, J I, Grasby, K L, Grove, J, Gudmundsson, O O, Hansen, C S, Hauberg, M E, Hollegaard, M V, Howrigan, D P, Huang, H, Maller, J B, Martin, A R, Martin, N G, Moran, J, Pallesen, J, Palmer, D S, Pedersen, C B, Pedersen, M G, Poterba, T, Poulsen, J B, Ripke, S, Robinson, E B, Satterstrom, F K, Stefansson, H, Stevens, C, Turley, P, Walters, G B, Won, H, Wright, M J, Andreassen, O A, Asherson, P, Burton, C L, Kuntsi, J, Sonuga-barke, E J S & Neale, B M & Plomin, R 2019, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ', Nature Genetics, vol. 51, no. 1, pp. 63-75 . https://doi.org/10.1038/s41588-018-0269-7
the 23 and Me Research Team, Demontis, D, Walters, R K, Martin, J, Mattheisen, M, Als, T D, Agerbo, E, Baldursson, G, Belliveau, R, Bybjerg-Grauholm, J, Bækvad-Hansen, M, Cerrato, F, Chambert, K, Churchhouse, C, Dumont, A, Eriksson, N, Gandal, M, Goldstein, J I, Grasby, K L, Grove, J, Gudmundsson, O O, Hansen, C S, Hauberg, M E, Hollegaard, M V, Howrigan, D P, Huang, H, Maller, J B, Martin, A R, Martin, N G, Moran, J, Pallesen, J, Palmer, D S, Pedersen, C B, Pedersen, M G, Poterba, T, Poulsen, J B, Ripke, S, Robinson, E B, Satterstrom, F K, Smith, G D, Davies, G E, Evans, D M, Kemp, J P, Ring, S, Stergiakouli, E, Pourcain, B S, Stoltenberg, C, Timpson, N J & Langley, K & Thapar, A & Medland, S E 2019, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ', Nature Genetics, vol. 51, no. 1, pp. 63-75 . https://doi.org/10.1038/s41588-018-0269-7
23andMe Research Team, ADHD Working Group of the Psychiatric Genomics Consortium (PGC) & Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium 2018, ' Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder ' Nature Genetics . https://doi.org/10.1038/s41588-018-0269-7
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
Nature Genetics, 51(1). Nature Publishing Group

Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute substantially to ADHD susceptibility, but no variants have been robust

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https://vbn.aau.dk/da/publications/2ea2ba33-e51e-4b07-a628-232327647cdd

Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

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Publikováno v: Molecular Psychiatry, 22, 2, pp. 192-201
Molecular psychiatry, 22(2), 192-201. Nature Publishing Group
Molecular Psychiatry, 22, 192. Nature Publishing Group
GCAN 2017, ' Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index ', Molecular Psychiatry, vol. 22, no. 2, pp. 192-201 . https://doi.org/10.1038/mp.2016.71
Molecular Psychiatry, 22(2), 192-201. Nature Publishing Group
Mol Psychiatry
Molecular Psychiatry, 22, 192-201
Hinney, A, Kesselmeier, M, Jall, S, Volckmar, A-L, Föcker, M, Antel, J, Heid, I M, Winkler, T W, Grant, S F A, Guo, Y, Bergen, A W, Kaye, W, Berrettini, W, Hakonarson, H, Herpertz-Dahlmann, B, de Zwaan, M, Herzog, W, Ehrlich, S, Zipfel, S, Egberts, K M, Adan, R, Brandys, M, van Elburg, A, Boraska Perica, V, Franklin, C S, Tschöp, M H, Zeggini, E, Bulik, C M, Collier, D, Scherag, A, Müller, T D, Hebebrand, J, GCAN, Hottenga, J J, Willemsen, G, Boomsma, D I, van Beijsterveldt, C E M, Middeldorp, C M & de Geus, E 2017, ' Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index ', Molecular Psychiatry, vol. 22, no. 2, pp. 192-201 . https://doi.org/10.1038/mp.2016.71
Molecular psychiatry 22(2), 192-201 (2017). doi:10.1038/mp.2016.71
Molecular psychiatry, vol 22, iss 2
Dipòsit Digital de la UB
Universidad de Barcelona
Molecular Psychiatry
Recercat. Dipósit de la Recerca de Catalunya
instname

The maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN) for prolonged periods of time. Prior to the onset of AN, premorbid body mass index (BMI) spans the entire range from underweight to obese. After recovery, patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0fa762e65248741075d19c9dc455b2
https://hdl.handle.net/2066/169662

A novel common variant in DCST2 is associated with length in early life and height in adulthood

Autor: van der Valk, R., Kreiner-Møller, E., Kooijman, M., Guxens, M., Stergiakouli, E., Sääf, A., Bradfield, J., Geller, F., Hayes, M., Cousminer, D., Körner, A., Thiering, E., Curtin, J., Myhre, R., Huikari, V., Joro, R., Kerkhof, M., Warrington, N., Pitkänen, N., Ntalla, I., Horikoshi, M., Veijola, R., Freathy, R., Teo, Y., Barton, S., Evans, D., Kemp, J., St Pourcain, B., Ring, S., Davey Smith, G., Bergström, A., Kull, I., Hakonarson, H., Mentch, F., Bisgaard, H., Chawes, B., Stokholm, J., Waage, J., Eriksen, P., Sevelsted, A., Melbye, M., van Duijn, C., Medina-Gomez, C., Hofman, A., de Jongste, J., Taal, H., Uitterlinden, A., Armstrong, L., Eriksson, J., Palotie, A., Bustamante, M., Estivill, X., Gonzalez, J., Llop, S., Kiess, W., Mahajan, A., Flexeder, C., Tiesler, C., Murray, C., Simpson, A., Magnus, P., Sengpiel, V., Hartikainen, A., Keinanen-Kiukaanniemi, S., Lewin, A., Da Silva Couto Alves, A., Blakemore, A., Buxton, J., Kaakinen, M., Rodriguez, A., Sebert, S., Vaarasmaki, M., Lakka, T., Lindi, V., Gehring, U., Postma, D., Ang, W., Newnham, J., Lyytikäinen, L., Pahkala, K., Raitakari, O., Panoutsopoulou, K., Zeggini, E., Boomsma, D., Groen-Blokhuis, M., Ilonen, J., Franke, L., Hirschhorn, J., Pers, T., Liang, L., Huang, J., Hocher, B., Knip, M., Saw, S., Holloway, J., Melén, E., Grant, S., Feenstra, B., Lowe, W., Widén, E., Sergeyev, E., Grallert, H., Custovic, A., Jacobsson, B., Jarvelin, M., Atalay, M., Koppelman, G., Pennell, C., Niinikoski, H., Dedoussis, G., Mccarthy, M., Frayling, T., Sunyer, J., Timpson, N., Rivadeneira, F., Bønnelykke, K., Jaddoe, V., Early Growth Genetics (EGG) Consortium

Publikováno v: Human Molecular Genetics

Common genetic variants have been identified for adult height, but not much is known about the genetics of skeletal growth in early life. To identify common genetic variants that influence fetal skeletal growth, we meta-analyzed 22 genome-wide associ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1874::d14139550d94a0e359729788dcffacbf
https://hdl.handle.net/11858/00-001M-0000-0028-65ED-511858/00-001M-0000-0028-65EB-9

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits.

Autor: Vogelezang S; The Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Bradfield JP; Quantinuum Research LLC, San Diego, California, United States of America.; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America., Ahluwalia TS; Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Bioinformatics Center, Department of Biology, University of Copenhagen, Copenhagen, Denmark., Curtin JA; Division of Infection Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, United Kingdom., Lakka TA; Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, Finland.; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Scholz M; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Monnereau C; The Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Stergiakouli E; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.; School of Oral and Dental Sciences, University of Bristol, Bristol, United Kingdom., Heiskala A; Center for Life Course Health Research, University of Oulu, Oulu, Finland., Horikoshi M; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom.; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Fedko IO; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Vilor-Tejedor N; ISGlobal, Barcelona, Spain.; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain.; BarcelonaBeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain., Cousminer DL; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America.; Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Standl M; Institute of Epidemiology, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany., Wang CA; School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle, Newcastle, Australia., Viikari J; Department of Medicine, University of Turku, Turku, Finland.; Division of Medicine, Turku University Hospital, Turku, Finland., Geller F; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Íñiguez C; CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.; Department of Statistics and Computational Research-Universitat de València, València, Spain.; Epidemiology and Environmental Health Joint Research Unit, FISABIO-Universitat Jaume I-Universitat de València, València, Spain., Pitkänen N; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland., Chesi A; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America., Bacelis J; Department of Obstetrics and Gynecology, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg, Gothenburg Sweden.; Region Västra Götaland, Sahlgrenska University Hospital, Department of Obstetrics and Gynecology, Gothenburg Sweden., Yengo L; University Lille, Centre National de la Recherche Scientifique, Institut Pasteur de Lille, UMR 8199-European Genomic Institute for Diabetes, Lille, France.; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia., Torrent M; Area de Salut de Menorca ib-salut, Menorca, Spain.; Institut d'Investigacio Sanitaria Illes Balears (IdISBa), Palma de Mallorca, Spain., Ntalla I; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom., Helgeland Ø; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Genetics and Bioinformatics, Health Data and Digitalization, Norwegian Institute of Public Health, Oslo, Norway., Selzam S; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom., Vonk JM; Department of Epidemiology, GRIAC (Groningen Research Institute for Asthma and COPD), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Zafarmand MH; Department of Public Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.; Department of Obstetrics & Gynecology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Heude B; Université de Paris, CRESS, INSERM, INRA, Paris, France., Farooqi IS; University of Cambridge Metabolic Research Laboratories and NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom., Alyass A; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada., Beaumont RN; Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Exeter, United Kingdom., Have CT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Rzehak P; Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, Ludwig-Maximilians Universität München (LMU), Munich, Germany., Bilbao JR; University of the Basque Country (UPV/EHU), Leioa, Spain.; Biocrues-Bizkaia Health Research Institute, Barakaldo, Spain.; CIBER Diabetes y Enfermedades Metabólicas (CIBERDEM), Spain., Schnurr TM; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Barroso I; Wellcome Sanger Institute, Cambridge, United Kingdom.; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Bønnelykke K; Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Beilin LJ; Medical School, The University of Western Australia, Perth, Western Australia, Australia., Carstensen L; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Charles MA; Université de Paris, CRESS, INSERM, INRA, Paris, France., Chawes B; Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Clément K; Nutrition and Obesities; systemic approaches research unit, Sorbonne University, INSERM, Pitie- Salpêtrière Hospital, Assistance Publique hôpital de Paris, Paris, France., Closa-Monasterolo R; Pediatrics, Nutrition and Development Research Unit, Universitat Rovira i Virgili, IISPV, Reus, Spain., Custovic A; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Eriksson JG; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Department of Obstetrics & Gynecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Escribano J; Pediatrics, Nutrition and Development Research Unit, Universitat Rovira i Virgili, IISPV, Reus, Spain., Groen-Blokhuis M; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Grote V; Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, Ludwig-Maximilians Universität München (LMU), Munich, Germany., Gruszfeld D; Neonatal Department, Children's Memorial Health Institute, Warsaw, Poland., Hakonarson H; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States of America., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hattersley AT; Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Exeter, United Kingdom.; NIHR Exeter Clinical Research Facility, College of Medicine and Health, University of Exeter, and Royal Devon and Exeter NHS Foundation Trust, Exeter, United Kingdom., Hollensted M; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Danish Diabetes Academy, Odense, Denmark., Hottenga JJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Hyppönen E; Australian Centre for Precision Health, University of South Australia Cancer Research Institute, Adelaide, Australia.; Population, Policy and Practice, UCL Institute of Child Health, University College London, London, United Kingdom.; South Australian Health and Medical Research Institute, Adelaide, Australia., Johansson S; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway., Joro R; Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Karhunen V; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, United Kingdom.; MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom., Kiess W; Center for Pediatric Research, University Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany., Knight BA; NIHR Exeter Clinical Research Facility, College of Medicine and Health, University of Exeter, and Royal Devon and Exeter NHS Foundation Trust, Exeter, United Kingdom., Koletzko B; Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, Ludwig-Maximilians Universität München (LMU), Munich, Germany., Kühnapfel A; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Landgraf K; Center for Pediatric Research, University Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.; Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany., Langhendries JP; CHC-Health Group, Liège, Belgium., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Leinonen JT; Institute For Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland., Li A; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada., Lindi V; University of Eastern Finland Library Kuopio, Kuopio, Finland., Lowry E; Center for Life Course Health Research, University of Oulu, Oulu, Finland.; Biocenter Oulu, Oulu University Hospital, Oulu, Finland., Bustamante M; ISGlobal, Barcelona, Spain.; CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Medina-Gomez C; The Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands., Melbye M; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.; Department of Medicine, Stanford School of Medicine, Stanford, California, United States of America., Michaelsen KF; Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Morgen CS; Department of Public Health, Section of Epidemiology, University of Copenhagen, Copenhagen, Denmark.; National Insitute of Public Health, University of Southern Denmark, Copenhagen, Denmark., Mori TA; Medical School, The University of Western Australia, Perth, Western Australia, Australia., Nielsen TRH; Department of Pediatrics, Hvidovre Hospital, Hvidovre, Denmark.; The Children's Obesity Clinic, Department of Pediatrics, Copenhagen University Hospital Holbæk, Holbæk, Denmark., Niinikoski H; Department of Physiology, University of Turku, Turku, Finland.; Department of Pediatrics, University of Turku, Turku, Finland., Oldehinkel AJ; Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center, Groningen, the Netherlands., Pahkala K; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Paavo Nurmi Centre, Sports and Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland., Panoutsopoulou K; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Pennell CE; School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle, Newcastle, Australia., Power C; Population, Policy and Practice, UCL Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Reijneveld SA; Department of Health Sciences, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Rivadeneira F; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands., Simpson A; Division of Infection Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, United Kingdom., Sly PD; Child Health Research Centre, University of Queensland, Brisbane, Australia.; World Health Organization, WHO Collaborating Centre for Children's Health and Environment, Brisbane, Queensland, Australia., Stokholm J; Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Teo KK; Department of Medicine, McMaster University, Hamilton, Canada; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada., Thiering E; Institute of Epidemiology, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany.; Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, Ludwig-Maximilians Universität München (LMU), Munich, Germany., Timpson NJ; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Uitterlinden AG; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging NCHA), Leiden, the Netherlands., van Beijsterveldt CEM; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., van Schaik BDC; Bioinformatics Laboratory, Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Vaudel M; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway., Verduci E; Department of Pediatrics, San Paolo Hospital, University of Milan, Milan, Italy., Vinding RK; Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Vogel M; Center for Pediatric Research, University Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.; Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany., Zeggini E; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom.; Institute of Translational Genomics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; TUM School of Medicine, Technical University of Munich and Klinikum Rechts der Isar, Munich, Germany., Sebert S; Center for Life Course Health Research, University of Oulu, Oulu, Finland.; Biocenter Oulu, Oulu University Hospital, Oulu, Finland.; Section of Genomics of Common Disease, Department of Medicine, Imperial College London, London, United Kingdom., Lind MV; Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Brown CD; Department of Genetics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America., Santa-Marina L; Consortium for Biomedical Research in Epidemiology and Public Health (CIBER en Epidemiologia y Salud Publica-CIBERESP), Barcelona, Spain.; Biodonostia Health Research Institute, San Sebastian, Spain.; Subdirección Salud Pública de Gipuzkoa, San Sebastian, Spain., Reischl E; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum Muenchen, Munich, Germany., Frithioff-Bøjsøe C; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Children's Obesity Clinic, Department of Pediatrics, Copenhagen University Hospital Holbæk, Holbæk, Denmark.; University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen N, Denmark., Meyre D; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada., Wheeler E; Wellcome Sanger Institute, Cambridge, United Kingdom.; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Ong K; Medical Research Council Epidemiology Unit & Department of Paediatrics, University of Cambridge, Addenbrooke's Hospital, Cambridge, England., Nohr EA; Research Unit for Gynaecology and Obstetrics, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark., Vrijkotte TGM; Department of Public Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Koppelman GH; University Medical Center Groningen, University of Groningen, Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, GRIAC (Groningen Research Institute for Asthma and COPD), Groningen, the Netherlands., Plomin R; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom., Njølstad PR; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Pediatrics and Adolescents, Haukeland University Hospital, Bergen, Norway.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America., Dedoussis GD; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Froguel P; University Lille, Centre National de la Recherche Scientifique, Institut Pasteur de Lille, UMR 8199-European Genomic Institute for Diabetes, Lille, France.; Section of Genomics of Common Disease, Department of Medicine, Imperial College London, London, United Kingdom., Sørensen TIA; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom.; Department of Public Health, Section of Epidemiology, University of Copenhagen, Copenhagen, Denmark., Jacobsson B; Department of Obstetrics and Gynecology, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg, Gothenburg Sweden.; Region Västra Götaland, Sahlgrenska University Hospital, Department of Obstetrics and Gynecology, Gothenburg Sweden.; Department of Genetics and Bioinformatics, Health Data and Digitalization, Norwegian Institute of Public Health, Oslo, Norway., Freathy RM; Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Exeter, United Kingdom.; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom., Zemel BS; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States of America.; Division of Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America., Raitakari O; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland., Vrijheid M; ISGlobal, Barcelona, Spain.; CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Cardiology, Heart Center, Tampere University Hospital, Tampere, Finland., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Kirsten H; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany., Holt PG; Telethon Kids Institute, The University of Western Australia, Perth, Western Australia, Australia., Heinrich J; Institute of Epidemiology, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany.; Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Inner City Clinic, University Hospital Munich, Ludwig-Maximilians-Universität of Munich, Munich, Germany.; Allergy and Lung Health Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia., Widén E; Institute For Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland., Sunyer J; ISGlobal, Barcelona, Spain.; CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain., Boomsma DI; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health research institute and Amsterdam Reproduction & Development research Institute, Amsterdam, the Netherlands., Järvelin MR; Center for Life Course Health Research, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, United Kingdom.; MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom., Körner A; Center for Pediatric Research, University Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.; Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany., Davey Smith G; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Holm JC; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Children's Obesity Clinic, Department of Pediatrics, Copenhagen University Hospital Holbæk, Holbæk, Denmark.; University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen N, Denmark., Atalay M; Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, Finland., Murray C; Division of Infection Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, United Kingdom., Bisgaard H; Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., McCarthy MI; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom.; Oxford National Institute for Health Research (NIHR) Biomedical Research Centre, Churchill Hospital, Oxford, United Kingdom., Jaddoe VWV; The Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands., Grant SFA; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America.; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America.; Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Neonatal Department, Children's Memorial Health Institute, Warsaw, Poland.; Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America., Felix JF; The Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.

Publikováno v: PLoS genetics [PLoS Genet] 2020 Oct 12; Vol. 16 (10), pp. e1008718. Date of Electronic Publication: 2020 Oct 12 (Print Publication: 2020).

Integrative multi-omics analysis of genomic, epigenomic, and metabolomics data leads to new insights for Attention-Deficit/Hyperactivity Disorder.

Autor: Hubers N; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Reproduction & Development (AR&D) Research Institute, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Hagenbeek FA; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Pool R; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Déjean S; Toulouse Mathematics Institute, UMR 5219, University of Toulouse, CNRS, Toulouse, France., Harms AC; Division of Analytical Biosciences, Leiden Academic Center for Drug Research, Leiden University, Leiden, the Netherlands.; The Netherlands Metabolomics Centre, Leiden, The Netherlands., Roetman PJ; LUMC-Curium, Department of Child and Adolescent Psychiatry, Leiden University Medical Center, Leiden, the Netherlands., van Beijsterveldt CEM; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Fanos V; Department of Surgical Sciences, University of Cagliari and Neonatal Intensive Care Unit, Cagliari, Italy., Ehli EA; Avera Institute for Human Genetics, Sioux Falls, South Dakota, USA., Vermeiren RRJM; LUMC-Curium, Department of Child and Adolescent Psychiatry, Leiden University Medical Center, Leiden, the Netherlands.; Youz, Parnassia Group, the Netherlands., Bartels M; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Hottenga JJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Hankemeier T; Division of Analytical Biosciences, Leiden Academic Center for Drug Research, Leiden University, Leiden, the Netherlands.; The Netherlands Metabolomics Centre, Leiden, The Netherlands., van Dongen J; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Reproduction & Development (AR&D) Research Institute, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Boomsma DI; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Reproduction & Development (AR&D) Research Institute, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.

Publikováno v: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics [Am J Med Genet B Neuropsychiatr Genet] 2024 Mar; Vol. 195 (2), pp. e32955. Date of Electronic Publication: 2023 Aug 03.