Scope and limitations of an efficient four-component reaction for dihydropyridin-2-ones

Autor: Scheffelaar, R., Paravidino, M., Znabet, A., Schmitz, R.F., de Kanter, F.J.J., Lutz, M., Spek, A.L., Fonseca Guerra, C., Bickelhaupt, F. M., Groen, M.B., Ruijter, E., Orru, R.V.A., SYNTHESE, Sub Crystal and Structural Chemistry, Dep Farmaceutische wetenschappen

Publikováno v: Scheffelaar, R, Paravidino, M, Znabet, A, Schmitz, R F, de Kanter, F J J, Lutz, M, Spek, A L, Guerra, C F, Bickelhaupt, F M, Groen, M B, Ruijter, E & Orru, R V A 2010, ' Scope and limitations of an efficient four-component reaction for dihydropyridin-2-ones ', Journal of Organic Chemistry, pp. 1723-1732 . https://doi.org/10.1021/jo902613j
Journal of Organic Chemistry, 75(5), 1723. American Chemical Society : Division of Carbohydrate Chemistry
Journal of Organic Chemistry, 1723-1732. American Chemical Society
STARTPAGE=1723;ENDPAGE=1732;ISSN=0022-3263;TITLE=Journal of Organic Chemistry

(Chemical Equation Presentation) A broad range of isonitrile-functionalized 3,4-dihydropyridin-2-ones could be prepared using a fourcomponent reaction between phosphonates, nitriles, aldehydes, and isocyanoacetates. The reaction involves initial form

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2620ae502fe4df107ab3b2317ac7552
https://dspace.library.uu.nl/handle/1874/202223

Multicomponent Synthesis of N-Heterocyclic Carbene Complexes

Autor: Bon, R.S., de Kanter, F.J.J., Lutz, M., Spek, A.L., Jahnke, M., Hahn, F.E., Groen, M.B., Orru, R.V.A., R¿ntgenparticipatieprogramma, Dep Scheikunde

Publikováno v: Organometallics, 26, 3639. American Chemical Society

N-Heterocyclic carbenes (NHCs) are valuable ligands in transition metal catalysis, due to their unique electronic properties. However, only a few routes toward unsymmetrically substituted, saturated NHCs are known. We have successfully applied the mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::a5974c7422773d9da62fd56c62a9137f
https://dspace.library.uu.nl/handle/1874/26893

A Mild Chemo-Enzymatic Oxidation-Hydrocyanation Cascade

Autor: Vugts, D.J., Veum, L., Al-Mafraji, K., Lemmens, R.H., Schmitz, R.F., de Kanter, F.J.J., Groen, M.B., Hanefeld, U., R.V.A., Orru

Publikováno v: Vugts, D J, Veum, L, Al-Mafraji, K, Lemmens, R H, Schmitz, R F, de Kanter, F J J, Groen, M B, Hanefeld, U & R.V.A., O 2006, ' A Mild Chemo-Enzymatic Oxidation-Hydrocyanation Cascade ', European Journal of Organic Chemistry, pp. 1672 . https://doi.org/10.1002/ejoc.200500905
European Journal of Organic Chemistry. Wiley-VCH Verlag

Oxidation-hydrocyanation of γ,δ-unsaturated alcohols using (immobilised) TEMPOXPhI(OAc)2 in combination with HbHNL proceeds smoothly. After (in situ) protection, the resulting cyanohydrin derivatives were obtained in good overall yields and high ee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::13d919c3f51d22763971f2b693d41273
https://research.vu.nl/en/publications/8e514d3d-f362-40a4-837d-e11235c8789b

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.