TCA cycle rewiring fosters metabolic adaptation to oxygen restriction in skeletal muscle from rodents and humans

Autor: Capitanio D. 1, Fania C. 2, Torretta E. 1, Vigano A 1, Moriggi M. 3, Bravatà V. 3, Caretti A. 4, Levett D.Z.H. 5, 6, 7, Grocott M.P.W. 5, Samaja M. 4, Cerretelli P. 3, Gelfi C. 8, 9

Publikováno v: Scientific reports (Nature Publishing Group) 7 (2017): 9723. doi:10.1038/s41598-017-10097-4
info:cnr-pdr/source/autori:Capitanio D. 1, Fania C. 2, Torretta E. 1, Vigano A 1, Moriggi M. 3, Bravatà V. 3, Caretti A. 4, Levett D.Z.H. 5,6,7, Grocott M.P.W. 5,6,7, Samaja M. 4, Cerretelli P. 3, Gelfi C. 8,9,10/titolo:TCA cycle rewiring fosters metabolic adaptation to oxygen restriction in skeletal muscle from rodents and humans/doi:10.1038%2Fs41598-017-10097-4/rivista:Scientific reports (Nature Publishing Group)/anno:2017/pagina_da:9723/pagina_a:/intervallo_pagine:9723/volume:7
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports

In mammals, hypoxic stress management is under the control of the Hypoxia Inducible Factors, whose activity depends on the stabilization of their labile α subunit. In particular, the skeletal muscle appears to be able to react to changes in substrat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e18a9ffcf1b47ab03d244739f60242e
https://doi.org/10.1038/s41598-017-10097-4