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pro vyhledávání: '"Grixti, Justine"'
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Autor:
Grixti, Justine M.1 justine.grixti@liverpool.ac.uk, Ayers, Duncan2,3 Duncan.Ayers@um.edu.mt, Day, Philip J. R.3 Philip.J.Day@manchester.ac.uk
Publikováno v:
Non-Coding RNA. Jun2021, Vol. 7 Issue 2, p1-15. 15p.
Akademický článek
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Publikováno v:
FRONTIERS IN PHARMACOLOGY
Grixti, J, O’Hagan, S, Day, P & Kell, D 2017, ' Enhancing drug efficacy and therapeutic index through cheminformatics-based selection of small molecule binary weapons that improve transportermediated targeting: a cytotoxicity system based on gemcitabine. ', Frontiers in Pharmacology . https://doi.org/10.3389/fphar.2017.00155
Grixti, J, O’Hagan, S, Day, P & Kell, D 2017, ' Enhancing drug efficacy and therapeutic index through cheminformatics-based selection of small molecule binary weapons that improve transportermediated targeting: a cytotoxicity system based on gemcitabine. ', Frontiers in Pharmacology . https://doi.org/10.3389/fphar.2017.00155
The transport of drug molecules is mainly determined by the distribution of influx and efflux transporters for which they are substrates. To enable tissue targeting, we sought to develop the idea that we might affect the transporter-mediated disposit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5596508183da9a02a458c089597fab15
Autor:
Grixti, Justine May, Farrugia, Claude, Hunter, Gary J., Hunter, Therese, Seventh National Chemistry Symposium
Superoxide dismutases (SODs) represent the first line of defense to counter oxidative stress caused by superoxide radicals, O2˙¯, these being the initial reduction products of oxygen, by catalysing their dismutation into O2 and H2O2. The latter is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3549::62d0c00ed017fce68254375cdd9cc886
Akademický článek
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Autor:
Superti-Furga, Giulio, Lackner, Daniel, Wiedmer, Tabea, Ingles-Prieto, Alvaro, Barbosa, Barbara, Girardi, Enrico, Goldmann, Ulrich, Gürtl, Bettina, Klavins, Kristaps, Klimek, Christoph, Lindinger, Sabrina, Liñeiro-Retes, Eva, Müller, André C., Onstein, Svenja, Redinger, Gregor, Reil, Daniela, Sedlyarov, Vitaly, Wolf, Gernot, Crawford, Matthew, Everley, Robert, Hepworth, David, Liu, Shenping, Noell, Stephen, Piotrowski, Mary, Stanton, Robert, Zhang, Hui, Corallino, Salvatore, Faedo, Andrea, Insidioso, Maria, Maresca, Giovanna, Redaelli, Loredana, Sassone, Francesca, Scarabottolo, Lia, Stucchi, Michela, Tarroni, Paola, Tremolada, Sara, Batoulis, Helena, Becker, Andreas, Bender, Eckhard, Chang, Yung-Ning, Ehrmann, Alexander, Müller-Fahrnow, Anke, Pütter, Vera, Zindel, Diana, Hamilton, Bradford, Lenter, Martin, Santacruz, Diana, Viollet, Coralie, Whitehurst, Charles, Johnsson, Kai, Leippe, Philipp, Baumgarten, Birgit, Chang, Lena, Ibig, Yvonne, Pfeifer, Martin, Reinhardt, Jürgen, Schönbett, Julian, Selzer, Paul, Seuwen, Klaus, Bettembourg, Charles, Biton, Bruno, Czech, Jörg, de Foucauld, Hélène, Didier, Michel, Licher, Thomas, Mikol, Vincent, Pommereau, Antje, Puech, Frédéric, Yaligara, Veeranagouda, Edwards, Aled, Bongers, Brandon J., Heitman, Laura H., IJzerman, Ad P., Sijben, Huub J., van Westen, Gerard J.P., Grixti, Justine, Kell, Douglas B., Mughal, Farah, Swainston, Neil, Wright-Muelas, Marina, Bohstedt, Tina, Burgess-Brown, Nicola, Carpenter, Liz, Dürr, Katharina, Hansen, Jesper, Scacioc, Andreea, Banci, Giulia, Colas, Claire, Digles, Daniela, Ecker, Gerhard, Füzi, Barbara, Gamsjäger, Viktoria, Grandits, Melanie, Martini, Riccardo, Troger, Florentina, Altermatt, Patrick, Doucerain, Cédric, Dürrenberger, Franz, Manolova, Vania, Steck, Anna-Lena, Sundström, Hanna, Wilhelm, Maria, Steppan, Claire M.
Publikováno v:
Nature Reviews Drug Discovery; July 2020, Vol. 19 Issue: 7 p429-430, 2p
Autor:
Roberts I; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Wright Muelas M; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK. m.wright-muelas@liverpool.ac.uk., Taylor JM; Department of Clinical Biochemistry and Metabolic Medicine, Liverpool Clinical Laboratories, Royal Liverpool University Hospitals Trust, Liverpool, UK., Davison AS; Department of Clinical Biochemistry and Metabolic Medicine, Liverpool Clinical Laboratories, Royal Liverpool University Hospitals Trust, Liverpool, UK., Xu Y; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.; Centre for Metabolomics Research (CMR), Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Grixti JM; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Gotts N; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.; Centre for Metabolomics Research (CMR), Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Sorokin A; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Goodacre R; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.; Centre for Metabolomics Research (CMR), Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK., Kell DB; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK. douglas.kell@liverpool.ac.uk.; Novo Nordisk Foundation Centre for Biosustainability, Technical University of Denmark, Building 220, Chemitorvet, 2000, Kgs Lyngby, Denmark. douglas.kell@liverpool.ac.uk.
Publikováno v:
Metabolomics : Official journal of the Metabolomic Society [Metabolomics] 2021 Dec 20; Vol. 18 (1), pp. 6. Date of Electronic Publication: 2021 Dec 20.
Autor:
Grixti JM; Institute of Integrative Biology, Faculty of Health & Life Sciences, University of Liverpool, Liverpool, L69 6ZB, UK, United Kingdom., Ayers D; Centre for Molecular Medicine and Biobanking, University of Malta, Msida, MSD2080, Malta.; Faculty of Biology, Medicine and Health Sciences, The University of Manchester, Manchester, M13 9PL, UK, United Kingdom.
Publikováno v:
Non-coding RNA research [Noncoding RNA Res] 2020 May 13; Vol. 5 (2), pp. 77-82. Date of Electronic Publication: 2020 May 13 (Print Publication: 2020).