Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Gritta, Janka"'
Autor:
Cornelia Knaak, Peter Nyvlt, Friederike S. Schuster, Claudia Spies, Patrick Heeren, Thomas Schenk, Felix Balzer, Paul La Rosée, Gritta Janka, Frank M. Brunkhorst, Didier Keh, Gunnar Lachmann
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-9 (2020)
Abstract Background Hemophagocytic lymphohistiocytosis (HLH) is a rare though often fatal hyperinflammatory syndrome mimicking sepsis in the critically ill. Diagnosis relies on the HLH-2004 criteria and HScore, both of which have been developed in pe
Externí odkaz:
https://doaj.org/article/3c64e1b2899b43a28b64032522f043c7
Autor:
Cornelia Knaak, Friederike S Schuster, Peter Nyvlt, Patrick Heeren, Claudia Spies, Thomas Schenk, Paul La Rosée, Gritta Janka, Frank M Brunkhorst, Gunnar Lachmann
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254345 (2021)
BackgroundFerritin is the major iron storage protein and an acute phase reactant. Hyperferritinemia is frequently seen in the critically ill where it has been hypothesized that not only underlying conditions but also factors such as transfusions, hem
Externí odkaz:
https://doaj.org/article/1d2ee66591754429a8a158bd0b673996
Autor:
Rafał Machowicz, Paul La Rosée, Paivi Miettunen, Gunnar Lachmann, Kai Lehmberg, Gernot Beutel, Karin Beutel, Matt S. Zinter, Jan-Inge Henter, Jan A M van Laar, Melissa Hines, Michael B. Jordan, Bita Shakoory, Gritta Janka, J Allyson Hays, AnnaCarin Horne, Tatiana von Bahr Greenwood
Publikováno v:
Critical Care Medicine, 50(5), 860-872
OBJECTIVE: Hemophagocytic lymphohistiocytosis is a hyperinflammatory syndrome that often requires critical care support and remains difficult to diagnose. These guidelines are meant to aid in the early recognition, diagnosis, supportive care, and tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aaf762d59abe6f7f267a07c7c604169
https://doi.org/10.1097/ccm.0000000000005361
https://doi.org/10.1097/ccm.0000000000005361
Autor:
Lachmann, Friederike S. Schuster, Peter Nyvlt, Patrick Heeren, Claudia Spies, Moritz F. Adam, Thomas Schenk, Frank M. Brunkhorst, Gritta Janka, Paul La Rosée, Cornelia Lachmann, Gunnar
Publikováno v:
Journal of Clinical Medicine; Volume 12; Issue 1; Pages: 192
Background: Elevated serum ferritin is a common condition in critically ill patients. It is well known that hyperferritinemia constitutes a good biomarker for hemophagocytic lymphohistiocytosis (HLH) in critically ill patients. However, further diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::ecfe8913f3970481fabdd1ac55365af3
Autor:
Kerstin Schütze, Miriam Groß, Kerstin Cornils, Katharina Wustrau, Sonja Schneppenheim, Henning Lenhartz, G. Christoph Korenke, Gritta Janka, Svea Ledig, Ingo Müller, Stephan Ehl, Kai Lehmberg
Publikováno v:
Blood advances.
Most hereditary forms of hemophagocytic lymphohistiocytosis (HLH) are caused by defects of cytotoxicity, including the vesicle trafficking disorder Griscelli syndrome type 2 (GS2, RAB27A deficiency). Deficiency of the mitogen-activated protein kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abc33269d36bce086e08472ff649c68
https://pubmed.ncbi.nlm.nih.gov/36206192
https://pubmed.ncbi.nlm.nih.gov/36206192
Autor:
Gritta Janka, Maurizio Aricò
Publikováno v:
Acta Paediatrica. 110:2723-2728
Familial haemophagocytic lymphohistiocytosis (FHL) is an inherited immune deficiency with defective cytotoxicity of natural killer cells and cytotoxic T lymphocytes. A highly stimulated, but ineffective immune response leads to severe hyperinflammati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4364291dbe6b7c666f8ad5a8e76755cf
https://doi.org/10.1111/apa.15889
https://doi.org/10.1111/apa.15889
Autor:
Johann Greil, Maria V. Verga-Falzacappa, Nicole E. Echner, Wolfgang Behnisch, Obul R. Bandapalli, Paulina Pechanska, Stephan Immenschuh, Vijith Vijayan, Jozsef Balla, Hirokatsu Tsukahara, Marion Schneider, Gritta Janka, Maren Claus, Thomas Longerich, Martina U. Muckenthaler, Andreas E. Kulozik
Publikováno v:
Haematologica, Vol 101, Iss 11 (2016)
Externí odkaz:
https://doaj.org/article/894e78a3117c41ca8ea07ae46102437e
Autor:
Cornelia Knaak, Gunnar Lachmann, Felix Balzer, Didier Keh, Frank M. Brunkhorst, Thomas Schenk, Peter Nyvlt, Friederike S Schuster, Gerald Vorderwülbecke, Claudia Spies, Paul La Rosée, Gritta Janka
Publikováno v:
Critical Care Medicine. 48:459-465
OBJECTIVE Hyperferritinemia is frequently seen in critically ill patients. A rather rare though life-threatening condition related to severely elevated ferritin is hemophagocytic lymphohistiocytosis. We analyze ferritin levels to differentiate hemoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b91e8b9c0dccd500674755deaf11e87
https://doi.org/10.1097/ccm.0000000000004131
https://doi.org/10.1097/ccm.0000000000004131
Autor:
Friederike S, Schuster, Peter, Nyvlt, Patrick, Heeren, Claudia, Spies, Moritz F, Adam, Thomas, Schenk, Frank M, Brunkhorst, Gritta, Janka, Paul, La Rosée, Cornelia, Lachmann, Gunnar, Lachmann
Background: Elevated serum ferritin is a common condition in critically ill patients. It is well known that hyperferritinemia constitutes a good biomarker for hemophagocytic lymphohistiocytosis (HLH) in critically ill patients. However, further diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0425738ee9adb0d1de85e1bdacce2c
Autor:
Gerald Vorderwülbecke, Gunnar Lachmann, Cornelia Knaak, Peter Nyvlt, Thomas Schenk, Felix Balzer, Frank M. Brunkhorst, Friederike S Schuster, Didier Keh, Claudia Spies, Paul La Rosée, Gritta Janka
Publikováno v:
Shock. 53:701-709
Background Hemophagocytic lymphohistiocytosis (HLH), an uncontrolled overactivation of the immune system, is well characterized in pediatric patients, yet, much less is known about this life-threatening condition in adult patients. As HLH is often co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9c62ddabb5fd3c373abec27b1671e3
https://doi.org/10.1097/shk.0000000000001454
https://doi.org/10.1097/shk.0000000000001454