Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Grit eLaue"'
Autor:
Gabrielle Elizabeth Callander, Morenike eOlorunda, Dominique eMonna, Edi eSchuepbach, Daniel eLangenegger, Claudia eBetschart, Samuel eHintermann, Dirk eBehnke, Simona eCotesta, Markus eFendt, Grit eLaue, Silvio eOfner, Emmanuelle eBriard, Christine E. Gee, Daniel eHoyer, Laura H. Jacobson
Publikováno v:
Frontiers in Neuroscience, Vol 7 (2013)
Orexin receptor antagonists represent attractive targets for the development of drugs for the treatment of insomnia. Both efficacy and safety are crucial in clinical settings and thorough investigations of pharmacokinetics and pharmacodynamics can pr
Externí odkaz:
https://doaj.org/article/22f5a7607e504a74a27938b07945c9b6
Autor:
Daniel eHoyer, Thomas eDürst, Markus eFendt, Laura H Jacobson, Claudia eBetschart, Samuel eHintermann, Dirk eBehnke, Simona eCotesta, Grit eLaue, Silvio eOfner, Eric eLegangneux, Christine E Gee
Publikováno v:
Frontiers in Neuroscience, Vol 7 (2013)
Dual orexin receptor (OXR) antagonists (DORAs) such as almorexant, SB-649868, suvorexant (MK-4305) and filorexant (MK-6096), have shown promise for the treatment of insomnias and sleep disorders. Whether antagonism of both OX1R and OX2R is necessary
Externí odkaz:
https://doaj.org/article/83dd9405703d4245af02f4011cce40ee