Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Grit Lynch"'
Autor:
Anna S. Gukovskaya, Grit Lynch, Jürgen Leser, Michael Beil, Thomas Seufferlein, Manfred P. Lutz, Stephen J. Pandol, Guido Adler
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 282:G450-G460
Pancreatic acinar cells depend on the integrity of the cytoskeleton for regulated secretion. Stimulation of isolated rat pancreatic acini with the secretagogue CCK serves as a model for human acute edematous pancreatitis. It induces the breakdown of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52957152f7b448eee8fbefd761034f47
https://doi.org/10.1152/ajpgi.00042.2001
https://doi.org/10.1152/ajpgi.00042.2001
Autor:
Manfred P. Lutz, Michael Beil, Grit Lynch, Luis J. Garcia-Marin, Sandra Kohler, Juergen Leser
Publikováno v:
Pflugers Archiv : European journal of physiology. 447(4)
Acinar cells require a functional apical actin web for secretion. During stimulation with supraphysiological concentrations of cholecystokinin (CCK), a condition that mimics acute pancreatitis, the actin filaments disintegrate. This leads to retentio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7679ef7d1975821692a774182f11794d
https://pubmed.ncbi.nlm.nih.gov/14634819
https://pubmed.ncbi.nlm.nih.gov/14634819
Autor:
Juergen Leser, Manfred P. Lutz, Lan Tang, Yoshikazu Tamori, Grit Lynch, William S. Trimble, Anne Marie F. Salapatek, Herbert Y. Gaisano, Laura Sheu
Publikováno v:
The Journal of clinical investigation. 108(11)
Exocytosis at the apical surface of pancreatic acinar cells occurs in the presence of physiological concentrations of cholecystokinin (CCK) but is inhibited at high concentrations. Here we show that Munc18c is localized predominantly to the basal mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a20b5b72b0f509a56387085dccc1fc
https://pubmed.ncbi.nlm.nih.gov/11733555
https://pubmed.ncbi.nlm.nih.gov/11733555