Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Griswold Dp"'
Autor:
Thomas H. Corbett, Griswold Dp
Publikováno v:
Cancer. 36:2441-2444
Colon tumors of mice were induced with 1, 2-dimethylhydrazine, N-nitroso-N-methylurethane, methylnitrosourea, and 4-methyl-N'-nitro-N-nitrosoguanidine. Of 82 transplantation attempts, four were successful, and the four tumors have been maintained as
Publikováno v:
Cancer Chemotherapy and Pharmacology. 29:190-194
Ethyl 5-amino-1,2-dihydro-2-methyl-3-phenylpyrido[3,4-b]pyrazin-7-ylcarbamate 2-hydroxyethanesulfonate hydrate (NSC 370 147) is a potent mitotic inhibitor, which has provided the basis for a candidate for clinical trial. As observed with clinically u
Autor:
Griswold Dp, Steadman D. Harrison
Publikováno v:
Cancer and Metastasis Reviews. 10:255-261
In this short essay, we have taken the opportunity to review briefly the history of anticancer drug screening, consider the changes that have been made throughout that history, and reflect on the suitability of current screening practices and the mod
Publikováno v:
Cancer Chemotherapy and Pharmacology. 25:425-429
Pyrazine diazohydroxide (sodium salt, NSC 361456; PZDH) is a new antitumor drug with relatively broad activity in initial evaluations against murine leukemias, solid tumors, and two human tumor xenografts in vivo. The present studies were designed to
Publikováno v:
Cancer Chemotherapy and Pharmacology. 31:255-257
The antimicrotubule agent taxol (NSC 125973) has shown clinical antitumor activity against several classically refractory tumors. We developed a drug-resistance profile for taxol using ten drug-resistant P388 leukemias to identify potentially useful
Publikováno v:
Journal of the National Cancer Institute. 84(7)
Autor:
Wayne K. Anderson, William R. Waud, Steadman D. Harrison, Jacqueline Plowman, Donald J. Dykes, Griswold Dp
Publikováno v:
Cancer chemotherapy and pharmacology. 30(4)
Carmethizole hydrochloride [1-methyl-2-methylthio-4,5-bis(hydroxymethyl)imidazole-4', 5'-bis(N-methylcarbamate)hydrochloride, NSC 602,668; hereafter called carmethizole] is a new antitumor drug that has shown relatively broad activity in initial eval
Publikováno v:
Cancer chemotherapy and pharmacology. 27(6)
Since 1978, over 50 clinically useful antitumor drugs or new candidate antitumor agents have been evaluated in vivo against cisplatin-resistant P388 leukemia (P388/DDPt) in our laboratories. Analysis of this data base has yielded insights into the cr
Publikováno v:
Cancer. 54:1160-1167
Publikováno v:
Pharmacology & Therapeutics. Part A: Chemotherapy, Toxicology and Metabolic Inhibitors. 1:411-435