Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Grishma Vadlamani"'
Autor:
Manasa Bharathwaj, Chaille T. Webb, Grishma Vadlamani, Christopher J. Stubenrauch, Tracy Palmer, Trevor Lithgow
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Bacteria can readily acquire plasmids via lateral gene transfer (LGT). These plasmids can carry genes for virulence and antimicrobial resistance (AMR).
Externí odkaz:
https://doaj.org/article/ea4f63369dcb4bf3b292063bf8fbfb7f
Autor:
Fatemeh Hajiaghaalipour, Angela Song, Grishma Vadlamani, Jingjing Zhang, Joshua Mylne, Richard Clark, K. Johan Rosengren
The stability of cyclic peptides, coupled with their structural diversity and ability to host an extensive range of bioactivities, make them promising leads for the development of new drugs. PawS-Derived Peptide-23 (PDP-23) is a head-to-tail macrocyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7ba69dcdb5983b2cb0a23f3d78fd7fc
https://doi.org/10.26434/chemrxiv-2023-s1g30
https://doi.org/10.26434/chemrxiv-2023-s1g30
Autor:
Angela Song, Mark F. Fisher, Jingjing Zhang, Carl Eliasson, Courtney E. McAleese, Grishma Vadlamani, Colton D. Payne, Fatemeh Hajiaghaalipour, Achala S. Jayasena, Richard J. Clark, Bastian Franke, K. Johan Rosengren, Rodney F. Minchin, Joshua S. Mylne
Publikováno v:
Chemical Science
Head-to-tail cyclized peptides are intriguing natural products with unusual properties. The PawS-Derived Peptides (PDPs) are ribosomally synthesized as part of precursors for seed storage albumins in species of the daisy family, and are post-translat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc21ac8c43d7af7356b0b51b75f46fd
http://europepmc.org/articles/PMC8132947
http://europepmc.org/articles/PMC8132947
Publikováno v:
Pest Management Science. 77:3807-3814
Resistance to antibiotics and herbicides are challenges with much in common. Antibiotic resistance became a risk in the 1950s, but a concerted global effort to manage it did not begin until after 2000. Widespread herbicide use began during the 1950s,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e6c18c9cf05ba8e054e94e08cc060c
https://doi.org/10.1002/ps.6357
https://doi.org/10.1002/ps.6357
Autor:
Joshua S. Mylne, Ulf Göransson, K. Johan Rosengren, Charles S. Bond, Håkan S. Andersson, Richard J. Clark, Fatemeh Hajiaghaalipour, Mark F. Fisher, Grishma Vadlamani, Colton D. Payne, Taj Muhammad
Publikováno v:
RSC Chemical Biology
Head-to-tail cyclic and disulfide-rich peptides are natural products with applications in drug design. Among these are the PawS-Derived Peptides (PDPs) produced in seeds of the daisy plant family. PDP-23 is a unique member of this class in that it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b8d484219130fa673a50c38d28e905
https://doi.org/10.1039/d1cb00155h
https://doi.org/10.1039/d1cb00155h
Autor:
Charles S. Bond, Keith A. Stubbs, Joel Haywood, Kirill V. Sukhoverkov, Joshua S. Mylne, Mark F. Fisher, Grishma Vadlamani, Karen J. Breese
Herbicides are vital for modern agriculture, but their utility is threatened by genetic or metabolic resistance in weeds as well as heightened regulatory scrutiny. Of the known herbicide modes of action, 6-hydroxymethyl-7,8-dihydropterin synthase (DH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3dada406e8cd8aa68f955795e82e393
https://doi.org/10.1101/2021.11.10.468163
https://doi.org/10.1101/2021.11.10.468163
Autor:
Chaille T. Webb, Grishma Vadlamani, Trevor Lithgow, Manasa Abhirami Bharathwaj, Tracy Palmer, Christopher J. Stubenrauch
Publikováno v:
mBio
mBio, Vol 12, Iss 3 (2021)
mBio, Vol 12, Iss 3 (2021)
The cell envelope of Gram-negative bacteria consists of two membranes surrounding the periplasm and peptidoglycan layer. β-Lactam antibiotics target the periplasmic penicillin-binding proteins that synthesize peptidoglycan, resulting in cell death.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77026dca44fc63366a0064017a574277
https://pubmed.ncbi.nlm.nih.gov/34154411
https://pubmed.ncbi.nlm.nih.gov/34154411
Autor:
Grishma Vadlamani, Kirill V. Sukhoverkov, Joel Haywood, Karen J. Breese, Mark F. Fisher, Keith A. Stubbs, Charles S. Bond, Joshua S. Mylne
Publikováno v:
Plant Communications. 3:100322
Herbicides are vital for modern agriculture, but their utility is threatened by genetic or metabolic resistance in weeds, as well as regulatory barriers. Of the known herbicide modes of action, 7,8-dihydropterin synthase (DHPS), which is involved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad38907fcf4403a569f31324797797f
https://doi.org/10.1016/j.xplc.2022.100322
https://doi.org/10.1016/j.xplc.2022.100322
Autor:
Jingjing Zhang, Mark F. Fisher, Joshua S. Mylne, Colton D. Payne, Richard J. Clark, K. Johan Rosengren, Grishma Vadlamani
Publikováno v:
Journal of natural products. 83(10)
Plants and their seeds have been shown to be a rich source of cystine-stabilized peptides. Recently a new family of plant seed peptides whose sequences are buried within precursors for seed storage vicilins was identified. Members of this Vicilin Bur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3313a18343c8dcc1a13a84ab46ea7e7f
https://pubmed.ncbi.nlm.nih.gov/32997497
https://pubmed.ncbi.nlm.nih.gov/32997497
Autor:
David J. Vocadlo, Jérôme Désiré, Grishma Vadlamani, Yves Blériot, Brian L. Mark, Keith A. Stubbs
Publikováno v:
Protein Science. 26:1161-1170
NagZ is an N-acetyl-β-d-glucosaminidase that participates in the peptidoglycan (PG) recycling pathway of Gram-negative bacteria by removing N-acetyl-glucosamine (GlcNAc) from PG fragments that have been excised from the cell wall during growth. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcf647b1ad37a6aee4e768ce61659bf7
https://doi.org/10.1002/pro.3166
https://doi.org/10.1002/pro.3166