Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Grisell Ortiz-Lasanta"'
Autor:
Maribel Rodríguez-Torres, Carlos F. Ríos-Bedoya, Grisell Ortiz-Lasanta, Acisclo M Marxuach-Cuétara, Josselyn Jiménez-Rivera
Publikováno v:
Annals of Hepatology, Vol 7, Iss 1, Pp 72-77 (2008)
Background: Thyroid dysfunction (TD) is associated to chronic hepatitis C (HCV) and interferon (IFN) therapy. The prevalence of TD at baseline and during IFN therapy among stages of hepatic fibrosis is unknown.Goals: To examine the frequency of TD at
Externí odkaz:
https://doaj.org/article/ade539913a24440495692f87b08aa5b7
Autor:
Rohit, Loomba, Eric J, Lawitz, Juan Pablo, Frias, Grisell, Ortiz-Lasanta, Lars, Johansson, Bridgette Boggess, Franey, Linda, Morrow, Moti, Rosenstock, Cynthia L, Hartsfield, Chao-Yin, Chen, Leo, Tseng, R Will, Charlton, Hank, Mansbach, Maya, Margalit
Publikováno v:
The Lancet Gastroenterology & Hepatology. 8:120-132
Management strategies for non-alcoholic steatohepatitis (NASH) are based predominantly on lifestyle modification, with no approved disease-modifying drugs yet available. We aimed to evaluate the safety, pharmacokinetics, and pharmacodynamics of pegoz
Autor:
Juan Pablo Frias, Grisell Ortiz-Lasanta, Cynthia L. Hartsfield, Leo Tseng, R. William Charlton, Hank Mansbach, Maya Margalit, Rohit Loomba
Publikováno v:
Metabolism. 128:155016
Autor:
Hank Mansbach, Leo Tseng, Chao-Yin Chen, R William Charlton, Juan P. Frias, Bridgette B. Franey, Maya Margalit, Eric Lawitz, Grisell Ortiz-Lasanta, Rohit Loomba, Linda Morrow
Publikováno v:
Journal of the Endocrine Society
Background: FGF21 is an endogenous hormone that regulates carbohydrate, lipid and energy metabolism. FGF21 analogs improve liver and metabolic abnormalities in non-alcoholic steatohepatitis (NASH). BIO89-100 is a long-acting glycoPEGylated FGF21, wit
Autor:
Jonathan Huang, Steven L. Flamm, Edward Gane, Maurizio Bonacini, Grisell Ortiz-Lasanta, Charles S. Landis, Benedict Maliakkal, Jie Zhang, Richard Robson, Stuart C. Gordon, Brian Kirby, Robert H. Hyland, Eric Lawitz, Shampa De-Oertel, Anu Osinusi, Diana M. Brainard
Publikováno v:
The lancet. Gastroenterologyhepatology. 5(10)
Summary Background There is a medical need for highly effective, safe, and well tolerated treatments for patients infected with hepatitis C virus (HCV) with severe renal impairment. We investigated the safety and efficacy of sofosbuvir with ribavirin
Autor:
Zobair M Younossi, Vlad Ratziu, Rohit Loomba, Mary Rinella, Quentin M Anstee, Zachary Goodman, Pierre Bedossa, Andreas Geier, Susanne Beckebaum, Philip N Newsome, David Sheridan, Muhammad Y Sheikh, James Trotter, Whitfield Knapple, Eric Lawitz, Manal F Abdelmalek, Kris V Kowdley, Aldo J Montano-Loza, Jerome Boursier, Philippe Mathurin, Elisabetta Bugianesi, Giuseppe Mazzella, Antonio Olveira, Helena Cortez-Pinto, Isabel Graupera, David Orr, Lise Lotte Gluud, Jean-Francois Dufour, David Shapiro, Jason Campagna, Luna Zaru, Leigh MacConell, Reshma Shringarpure, Stephen Harrison, Arun J Sanyal, Manal Abdelmalek, Gary Abrams, Humberto Aguilar, Aijaz Ahmed, Elmar Aigner, Guruprasad Aithal, Aftab Ala, William Alazawi, Agustin Albillos, Michael Allison, Sfa Al-Shamma, Raul Andrade, Pietro Andreone, Mario Angelico, Victor Ankoma-Sey, Quentin Anstee, Rodolphe Anty, Victor Araya, Juan Ignacio Arenas Ruiz, Perttu Arkkila, Marty Arora, Tarik Asselah, Jennifer Au, Oyekoya Ayonrinde, Robert James Bailey, Maya Balakrishnan, Kiran Bambha, Meena Bansal, Sidney Barritt, John Bate, Jorge Beato, Jaideep Behari, Pablo Bellot, Ziv Ben Ari, Michael Bennett, Marina Berenguer, Benedetta Terziroli Beretta-Piccoli, Thomas Berg, Maurizio Bonacini, Lucia Bonet, Brian Borg, Marc Bourliere, William Bowman, David Bradley, Marija Brankovic, Marius Braun, Jean-Pierre Bronowicki, Savino Bruno, Cindy Cai, Amy Calderon, José Luis Calleja Panero, Elizabeth Carey, Michal Carmiel, Jose Antonio Carrión, Matthew Cave, Cristina Chagas, Tawfik Chami, Alan Chang, Allan Coates, Jeremy Cobbold, Charlote Costentin, Kathleen Corey, Lynsey Corless, Javier Crespo, Oscar Cruz Pereira, Victor de Ledinghen, Andrew deLemos, Moises Diago, Mamie Dong, Jean-François Dufour, Predrag Dugalic, Winston Dunn, Magby Elkhashab, Michael Epstein, Maria Desamparados Escudero-Garcia, Ohad Etzion, Larry Evans, Robert Falcone, Conrado Fernandez, Jose Ferreira, Scott Fink, Kevin Finnegan, Roberto Firpi-Morell, Annarosa Floreani, Thierry Fontanges, Ryan Ford, Ewan Forrest, Andrew Fowell, Anna Ludovica Fracanzani, Sven Francque, Bradley Freilich, Juan Frias, Michael Fuchs, Javier Fuentes, Michael Galambos, Juan Gallegos, Anja Geerts, Jacob George, Maged Ghali, Reem Ghalib, Pierre Gholam, Pere Gines, Norman Gitlin, Tobias Goeser, John Goff, Stuart Gordon, Frederic Gordon, Odile Goria, Shaun Greer, Alla Grigorian, Henning Gronbaek, Maeva Guillaume, Naresh Gunaratnam, Dina Halegoua-De Marzio, Bilal Hameed, Stephanie Hametner, James Hamilton, Marek Hartleb, Tarek Hassanein, Dieter Häussinger, Paul Hellstern, Robert Herring, Eva Heurich, Christophe Hezode, Holger Hinrichsen, Peter Holland Fischer, Yves Horsmans, Jonathan Huang, Hyder Hussaini, Antoine Jakiche, Lennox Jeffers, Blake Jones, Rosa Jorge, Francisco Jorquera, Shoba Joshi, Alisan Kahraman, Kelly Kaita, Nicholas Karyotakis, Zeid Kayali, Stergios Kechagias, Thomas Kepczyk, Mandana Khalili, Hicham Khallafi, Johannes Kluwe, Anita Kohli, Kevin Korenblat, Kris Kowdley, Aleksander Krag, Richard Krause, Andreas Kremer, Karen Krok, Miodrag Krstic, Marcelo Kugelmas, Sonal Kumar, Scott Kuwada, Damien Labarriere, Michelle Lai, Wim Laleman, Pietro Lampertico, Alice Lee, Vincent Leroy, Steven Lidofsky, Tina Huey Lim, Joseph Lim, Donald Lipkis, Ester Little, Amadeo Lonardo, Michelle Long, Velimir Anthony Christopher Luketic, Yoav Lurie, Guilherme Macedo, Joana Magalhaes, Mihály Makara, Benedict Maliakkal, Michael Manns, Pinelopi Manousou, Parvez Mantry, Giulio Marchesini, Carla Marinho, Paul Marotta, Hanns-Ulrich Marschall, Linda Martinez, Marlyn Mayo, Mark McCullen, William McLaughlin, Uta Merle, Raphael Merriman, Apurva Modi, Esther Molina, Aldo Montano-Loza, Carlos Monteverde, Amilcar Morales Cardona, Sulleman Moreea, Christophe Moreno, Filomena Morisco, Abdullah Mubarak, Beat Muellhaupt, Sandeep Mukherjee, Tobias Müller, Aleksandar Nagorni, Jahnavi Naik, Guy Neff, Moises Nevah, Philip Newsome, Eric Nguyen-Khac, Mazen Noureddin, Jude Oben, Hans Orlent, James Orr, Grisell Ortiz-Lasanta, Violaine Ozenne, Prashant Pandya, Angelo Paredes, James Park, Joykumar Patel, Keyur Patel, Sonali Paul, Heather Patton, Markus Peck-Radosavljevic, Salvatore Petta, Stephen Pianko, Anna Piekarska, Neville Pimstone, Joseph Pisegna, Paul Pockros, Stanislas Pol, Michael Porayko, John Poulos, David Pound, Joe Pouzar, Jose Presa Ramos, Nikolaos Pyrsopoulos, Nila Rafiq, Kate Muller, Alnoor Ramji, Ravi Ravinuthala, Chakradhar Reddy, Gautham Reddy K G, K. Rajender Reddy K R, Frederic Regenstein, Robert Reindollar, Justin Reynolds, Andres Riera, Jose Rivera Acosta, Geert Robaeys, Stuart Roberts, Federico Rodriguez-Perez, Sandor Romero, Manuel Romero-Gomez, Raymond Rubin, Mariagrazia Rumi, Simon Rushbrook, Christian Rust, Michael Ryan, Rifaat Safadi, Adnan Said, Kimmo Salminen, Didier Samuel, John Santoro, Arun Sanyal, Souvik Sarkar, Cynthia Schaeffer, Jörn Schattenberg, Ingolf Schiefke, Eugene Schiff, Wolfgang Schmidt, Jeffrey Schneider, Jeoffrey Schouten, Michael Schultz, Giada Sebastiani, David Semela, Thomas Sepe, Aasim Sheikh, Muhammad Sheikh, Kenneth Sherman, Oren Shibolet, Mitchell Shiffman, Asma Siddique, Cyril Sieberhagen, Samuel Sigal, Katarzyna Sikorska, Krzysztof Simon, Marie Sinclair, Richard Skoien, Joel Solis, Siddharth Sood, Bob Souder, James Spivey, Per Stal, Laura Stinton, Simone Strasser, Petar Svorcan, Gyongzi Szabo, Andrew Talal, Edward Tam, Brent Tetri, Paul Thuluvath, Hillel Tobias, Krzysztof Tomasiewicz, Dawn Torres, Albert Tran, Michael Trauner, Christian Trautwein, Emanuel Tsochatzis, Esther Unitt, Victor Vargas, Istvan Varkonyi, Ella Veitsman, Umberto Vespasiani Gentilucci, David Victor, John Vierling, Catherine Vincent, Aron Vincze, Manfred von der Ohe, Natasha Von Roenn, Raj Vuppalanchi, Michael Waters, Kymberly Watt, Julia Wattacheril, Martin Weltman, Amanda Wieland, Gregory Wiener, Alonzo Williams A, Jeffrey Williams J, Jason Wilson, Maria Yataco, Eric Yoshida, Ziad Younes, Liyun Yuan, Adam Zivony, Donald Zogg, Heinz Zoller, Fabien Zoulim, Eli Zuckerman, Massimo Zuin
Publikováno v:
REGENERATE Study Investigators 2019, ' Obeticholic acid for the treatment of non-alcoholic steatohepatitis : interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial ', The Lancet, vol. 394, no. 10215, pp. 2184-2196 . https://doi.org/10.1016/S0140-6736(19)33041-7
The lancet : international edition
Younossi, Z M, Ratziu, V, Loomba, R, Rinella, M, Anstee, Q M, Goodman, Z, Bedossa, P, Geier, A, Beckebaum, S, Newsome, P N, Sheridan, D, Sheikh, M Y, Trotter, J, Knapple, W, Lawitz, E, Abdelmalek, M F, Kowdley, K V, Montano-Loza, A J, Boursier, J, Mathurin, P, Bugianesi, E, Mazzella, G, Olveira, A, Cortez-Pinto, H, Graupera, I, Orr, D, Gluud, L L, Dufour, J-F, Shapiro, D, Campagna, J, Zaru, L, MacConell, L, Shringarpure, R, Harrison, S, Sanyal, A J & REGENERATE Study Investigators 2019, ' Obeticholic acid for the treatment of non-alcoholic steatohepatitis : interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial ', The Lancet, vol. 394, no. 10215, pp. 2184-2196 . https://doi.org/10.1016/S0140-6736(19)33041-7
The lancet : international edition
Younossi, Z M, Ratziu, V, Loomba, R, Rinella, M, Anstee, Q M, Goodman, Z, Bedossa, P, Geier, A, Beckebaum, S, Newsome, P N, Sheridan, D, Sheikh, M Y, Trotter, J, Knapple, W, Lawitz, E, Abdelmalek, M F, Kowdley, K V, Montano-Loza, A J, Boursier, J, Mathurin, P, Bugianesi, E, Mazzella, G, Olveira, A, Cortez-Pinto, H, Graupera, I, Orr, D, Gluud, L L, Dufour, J-F, Shapiro, D, Campagna, J, Zaru, L, MacConell, L, Shringarpure, R, Harrison, S, Sanyal, A J & REGENERATE Study Investigators 2019, ' Obeticholic acid for the treatment of non-alcoholic steatohepatitis : interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial ', The Lancet, vol. 394, no. 10215, pp. 2184-2196 . https://doi.org/10.1016/S0140-6736(19)33041-7
© 2019 Elsevier Ltd. All rights reserved.
Background: Non-alcoholic steatohepatitis (NASH) is a common type of chronic liver disease that can lead to cirrhosis. Obeticholic acid, a farnesoid X receptor agonist, has been shown to improve the his
Background: Non-alcoholic steatohepatitis (NASH) is a common type of chronic liver disease that can lead to cirrhosis. Obeticholic acid, a farnesoid X receptor agonist, has been shown to improve the his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b4774824d4fc96584556df1079fe77
Autor:
Grisell Ortiz-Lasanta, Diana M. Brainard, John G. McHutchison, Stuart C. Gordon, Benedict Maliakkal, Shampa De-Oertel, Erik Mogalian, Edward Gane, Jie Zhang, Charles Landis, Anu Osinusi, Steven L. Flamm, Maurizio Bonacini, Hai Cheng Huang, Eric Lawitz, Christina Sze Man Yip
Publikováno v:
Clinical Hepatology.
Background Despite higher concentrations of the primary circulating sofosbuvir (SOF) metabolite, GS-331007, in patients with severe renal impairment (RI), retrospective case series and claims database analyses have suggested substantial use of ledipa
Autor:
James N. Cooper, Ziad Younes, Reem Ghalib, Grisell Ortiz-Lasanta, Trevor Hawkins, Norman Gitlin, Jacob Lalezari, Fiona McPhee, David E. Bernstein, Paul J. Pockros, Delphine Hennicken, William Harlan, Eric Hughes, Khurram Rana, Natarajan Ravendhran, Paul J. Thuluvath, Eric Lawitz, Peter Varunok, David R. Nelson, Kris V. Kowdley, Mordechai Rabinovitz, B. Freilich, Aasim Sheikh, Godson Oguchi, Michael J. Bennett
Publikováno v:
Hepatology (Baltimore, Md.)
Chronic infection with hepatitis C virus (HCV) genotype 3 is common throughout the world and remains a significant disease burden for many patients.1,2 Infection with HCV genotype 3 has been associated with an increased risk of progression to cirrhos
Autor:
Josselyn Jiménez-Rivera, Maribel Rodríguez-Torres, Grisell Ortiz-Lasanta, Dagmary Purcell-Arevalo, Carlos F. Ríos-Bedoya, Acisclo M. Marxuach-Cuétara
Publikováno v:
Journal of Medical Virology. 80:1576-1580
Efficacy of chronic hepatitis C (CHC) treatment with Peg-IFN and Ribavirin (RBV) is superior for genotypes 2/3 (GT-2/3) than for genotype 1 (GT-1) patients. Efficacy of treatment in Latinos infected with GT-2/3 is unknown. The purpose of the study wa
Autor:
Michael R Bennett, Edward Tam, Edmund Tse, Brian Conway, Fred Poordad, Victor de Ledinghen, Samuel S. Lee, Grisell Ortiz-Lasanta, Navdeep Boparai, Philip D. Yin, Mark S. Sulkowski, Lindsay Mollison, Fiona McPhee, Norbert Bräu, Andrew J. Muir, Nathalie Boyer, Jean-Pierre Bronowicki, Stanislas Pol, James E. Levin, E. Scott Swenson, Ira M. Jacobson, Peter W Angus, Thomas Sepe, K. Rajender Reddy, William Sievert, Eric Hughes
Publikováno v:
JAMA Ophthalmology
JAMA Ophthalmology, American Medical Association 2015, 313 (17), pp.1728-1735. ⟨10.1001/jama.2015.3860⟩
JAMA Ophthalmology, American Medical Association 2015, 313 (17), pp.1728-1735. ⟨10.1001/jama.2015.3860⟩
The antiviral activity of all-oral, ribavirin-free, direct-acting antiviral regimens requires evaluation in patients with chronic hepatitis C virus (HCV) infection.To determine the rates of sustained virologic response (SVR) in patients receiving the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023f4cd78d03942001c9470e01f062bb
https://hal.univ-lorraine.fr/hal-01679637
https://hal.univ-lorraine.fr/hal-01679637