Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Grimsey, Ian M."'
Yes
Globular proteins are important both as therapeutic agents and excipients. However, their fragile native conformations can be denatured during pharmaceutical processing, which leads to modification of the surface energy of their powders and
Globular proteins are important both as therapeutic agents and excipients. However, their fragile native conformations can be denatured during pharmaceutical processing, which leads to modification of the surface energy of their powders and
Externí odkaz:
http://hdl.handle.net/10454/8700
Yes
It is important for the formulators of biopharmaceuticals to predict the folding–unfolding transition of proteins. This enables them to process proteins under predetermined conditions, without denaturation. Depending on the apparent denatu
It is important for the formulators of biopharmaceuticals to predict the folding–unfolding transition of proteins. This enables them to process proteins under predetermined conditions, without denaturation. Depending on the apparent denatu
Externí odkaz:
http://hdl.handle.net/10454/8706
Bulk crystallisation of protein therapeutic molecules towards their controlled drug delivery is of interest to the biopharmaceutical industry. The complexity of biotherapeutic molecules is likely to lead to complex material properties of crystals in
Externí odkaz:
http://hdl.handle.net/10454/7363
Mannitol is a polymorphic pharmaceutical excipient, which commonly exists in three forms: alpha, beta and delta. Each polymorph has a needle-like morphology, which can give preferred orientation effects when analysed by X-ray powder diffractometry (X
Externí odkaz:
http://hdl.handle.net/10454/3288
The surface energy of a-lactose monohydrate measured by inverse gas chromatography (IGC) is reported along with a dynamic molecular modelling study of the interaction of the various molecular probes with different surfaces of a-lactose monohydrate. T
Externí odkaz:
http://hdl.handle.net/10454/4623
In this paper, molecular modelling was used to investigate the nature of probe/surface interactions during the analysis of Dß-mannitol using inverse gas chromatography (IGC). IGC was used to experimentally measure the dispersive components of surfac
Externí odkaz:
http://hdl.handle.net/10454/3441
Purpose The purpose of the article was to study melt sonocrystallization (MSC) for a drug forming a viscous melt when processed below its glass transition temperature. Methods A molten mass of drug was poured in a vessel containing deionized water, m
Externí odkaz:
http://hdl.handle.net/10454/2978
Autor:
Sunkersett, Mohit R., Grimsey, Ian M., Doughty, Stephen W., Osburn, John C., York, Peter, Rowe, Raymond C.
The surface energetic parameters of carbamazepine and paracetamol have been studied using inverse gas chromatography modified to produce dry and ambient conditions within the column. The values of the dispersive component of the surface free energy (
Externí odkaz:
http://hdl.handle.net/10454/3453
Autor:
Mohammad, Mohammad Amin, Grimsey, Ian M., Forbes, Robert T., Blagbrough, Ian S., Conway, Barbara R
Publikováno v:
In Colloids and Surfaces B: Biointerfaces 1 October 2016 146:700-706
Publikováno v:
In Journal of Pharmaceutical and Biomedical Analysis 10 October 2015 114:176-183