A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response.

Autor: Leibel SL; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093.; Sanford Consortium for Regenerative Medicine, La Jolla, CA 92037., McVicar RN; Sanford Consortium for Regenerative Medicine, La Jolla, CA 92037.; Sanford Burnham Prebys Medical Discovery Institute, Center for Stem Cells & Regenerative Medicine, La Jolla, CA 92037., Murad R; Sanford Burnham Prebys Medical Discovery Institute, Center for Stem Cells & Regenerative Medicine, La Jolla, CA 92037., Kwong EM; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093.; Sanford Consortium for Regenerative Medicine, La Jolla, CA 92037.; Sanford Burnham Prebys Medical Discovery Institute, Center for Stem Cells & Regenerative Medicine, La Jolla, CA 92037., Clark AE; Department of Medicine, University of California San Diego, La Jolla, CA 92093., Alvarado A; Sanford Consortium for Regenerative Medicine, La Jolla, CA 92037.; Sanford Burnham Prebys Medical Discovery Institute, Center for Stem Cells & Regenerative Medicine, La Jolla, CA 92037., Grimmig BA; Sanford Consortium for Regenerative Medicine, La Jolla, CA 92037.; Sanford Burnham Prebys Medical Discovery Institute, Center for Stem Cells & Regenerative Medicine, La Jolla, CA 92037., Nuryyev R; Sanford Consortium for Regenerative Medicine, La Jolla, CA 92037.; Sanford Burnham Prebys Medical Discovery Institute, Center for Stem Cells & Regenerative Medicine, La Jolla, CA 92037., Young RE; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093., Lee JC; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093., Peng W; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093., Zhu YP; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093., Griffis E; Nikon Imaging Center, University of California San Diego, La Jolla, CA 92093., Nowell CJ; Monash Institute of Pharmaceutical Sciences, Parkville, VIC 3052, Australia., James B; Sanford Burnham Prebys Medical Discovery Institute, Center for Stem Cells & Regenerative Medicine, La Jolla, CA 92037., Alarcon S; La Jolla Institute for Immunology, La Jolla, CA 92037., Malhotra A; Division of Pulmonary, Critical Care, and Sleep Medicine, University of California San Diego, La Jolla, CA 92093., Gearing LJ; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.; Department of Molecular and Translational Sciences, Monash University Clayton, Clayton, VIC 3168, Australia., Hertzog PJ; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC 3168, Australia.; Department of Molecular and Translational Sciences, Monash University Clayton, Clayton, VIC 3168, Australia., Galapate CM; Sanford Burnham Prebys Medical Discovery Institute Cell & Molecular Biology of Cancer, La Jolla, CA 92037., Galenkamp KMO; Sanford Burnham Prebys Medical Discovery Institute, Center for Stem Cells & Regenerative Medicine, La Jolla, CA 92037., Commisso C; Sanford Burnham Prebys Medical Discovery Institute Cell & Molecular Biology of Cancer, La Jolla, CA 92037., Smith DM; Department of Medicine, University of California San Diego, La Jolla, CA 92093., Sun X; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093., Carlin AF; Department of Medicine, University of California San Diego, La Jolla, CA 92093., Sidman RL; Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115., Croker BA; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093., Snyder EY; Sanford Consortium for Regenerative Medicine, La Jolla, CA 92037.; Sanford Burnham Prebys Medical Discovery Institute, Center for Stem Cells & Regenerative Medicine, La Jolla, CA 92037.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jul 23; Vol. 121 (30), pp. e2408109121. Date of Electronic Publication: 2024 Jul 19.

Exercise reduces the anxiogenic effects of meta-chlorophenylpiperazine: The role of 5-HT2C receptors in the bed nucleus of the stria terminalis.

Autor: Fox JH; Department of Psychological Science, University of Vermont, Burlington, VT, United States., Boucher MN; Department of Psychological Science, University of Vermont, Burlington, VT, United States., Abedrabbo KS; Department of Psychological Science, University of Vermont, Burlington, VT, United States., Hare BD; Department of Psychological Science, University of Vermont, Burlington, VT, United States., Grimmig BA; Department of Psychological Science, University of Vermont, Burlington, VT, United States., Falls WA; Department of Psychological Science, University of Vermont, Burlington, VT, United States., Hammack SE; Department of Psychological Science, University of Vermont, Burlington, VT, United States.

Publikováno v: Frontiers in synaptic neuroscience [Front Synaptic Neurosci] 2023 Jan 13; Vol. 14, pp. 1067420. Date of Electronic Publication: 2023 Jan 13 (Print Publication: 2022).

Targeting Mitochondrial Complex I Deficiency in MPP⁺/MPTP-induced Parkinson's Disease Cell Culture and Mouse Models by Transducing Yeast NDI1 Gene.

Autor: Li, Hongzhi¹ (AUTHOR) lhz@wmu.edu.cn, Zhang, Jing² (AUTHOR), Shen, Yuqi¹ (AUTHOR), Ye, Yifan¹ (AUTHOR), Jiang, Qingyou¹ (AUTHOR), Chen, Lan¹ (AUTHOR), Sun, Bohao² (AUTHOR), Chen, Zhuo¹ (AUTHOR), Shen, Luxi³ (AUTHOR), Fang, Hezhi¹ (AUTHOR), Yang, Jifeng¹ (AUTHOR) yjf@wmu.edu.cn, Gu, Haihua¹ (AUTHOR) haihuagu@wmu.edu.cn

Publikováno v: Biological Procedures Online. 4/9/2024, Vol. 26 Issue 1, p1-15. 15p.

APOE4 genotype and aging impair injury-induced microglial behavior in brain slices, including toward Aβ, through P2RY12.

Autor: Sepulveda, Jordy¹ (AUTHOR), Kim, Jennifer Yejean² (AUTHOR), Binder, Joseph² (AUTHOR), Vicini, Stefano¹ (AUTHOR), Rebeck, G. William² (AUTHOR) gwr2@georgetown.edu

Publikováno v: Molecular Neurodegeneration. 3/11/2024, Vol. 19 Issue 1, p1-17. 17p.

Distinct microglial transcriptomic signatures within the hippocampus.

Autor: Chintamen, Sana¹ (AUTHOR), Gaur, Pallavi² (AUTHOR), Vo, Nicole² (AUTHOR), Bradshaw, Elizabeth M.² (AUTHOR), Menon, Vilas² (AUTHOR), Kernie, Steven G.^1,2 (AUTHOR) sk3516@cumc.columbia.edu

Publikováno v: PLoS ONE. 1/5/2024, Vol. 19 Issue 1, p1-64. 64p.