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Deglycosylated Anti-Aβ Antibody Dose–Response Effects on Pathology and Memory in APP Transgenic Mice
Autor:
Marcia N. Gordon, Jaume Pons, Arnon Rosenthal, Dave Morgan, Victoria Ronan, Paul E. Gottschall, Rachel Karlnoski, Jennifer Alamed, Grimm Jan Markus
Publikováno v:
Journal of Neuroimmune Pharmacology. 3:187-197
Anti-Abeta antibody administration to amyloid-depositing transgenic mice can reverse amyloid pathology and restore memory function. However, in old mice, these treatments also increase vascular leakage and promote formation of vascular amyloid deposi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74964988d357449a717c7f2f46283e1
https://doi.org/10.1007/s11481-008-9114-6
https://doi.org/10.1007/s11481-008-9114-6
