Zobrazeno 1 - 10
of 3 492
pro vyhledávání: '"Grima, P."'
We report the existence of deterministic patterns in plots showing the relationship between the mean and the Fano factor (ratio of variance and mean) of stochastic count data. These patterns are found in a wide variety of datasets, including those fr
Externí odkaz:
http://arxiv.org/abs/2405.17530
Motivated by the refreezing of melt water in firn we revisit the one-dimensional percolation of liquid water and non-reactive gas in porous ice. We analyze the dynamics of infiltration in the absence of capillary forces and heat conduction to underst
Externí odkaz:
http://arxiv.org/abs/2403.15996
We introduce a biologically detailed, stochastic model of gene expression describing the multiple rate-limiting steps of transcription, nuclear pre-mRNA processing, nuclear mRNA export, cytoplasmic mRNA degradation and translation of mRNA into protei
Externí odkaz:
http://arxiv.org/abs/2401.12661
Autor:
Pablo Gómez-del Arco, Joan Isern, Daniel Jimenez-Carretero, Dolores López-Maderuelo, Rebeca Piñeiro-Sabarís, Fadoua El Abdellaoui-Soussi, Carlos Torroja, María Linarejos Vera-Pedrosa, Mercedes Grima-Terrén, Alberto Benguria, Ana Simón-Chica, Antonio Queiro-Palou, Ana Dopazo, Fátima Sánchez-Cabo, José Jalife, José Luis de la Pompa, David Filgueiras-Rama, Pura Muñoz-Cánoves, Juan Miguel Redondo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Extensive genetic studies have elucidated cardiomyocyte differentiation and associated gene networks using single-cell RNA-seq, yet the intricate transcriptional mechanisms governing cardiac conduction system (CCS) development and working ca
Externí odkaz:
https://doaj.org/article/6e6e018aa0f54c20af7b9385311cf831
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-7 (2024)
Abstract Mantle plumes are responsible for the Earth’s largest volcanic provinces. In the prevailing paradigm, the deep mantle is less degassed than convecting shallow mantle, implying that plume-derived lavas have higher concentrations of primordi
Externí odkaz:
https://doaj.org/article/04f0934100a144e78b662e5a66caee0a
Autor:
Chen Jia, Ramon Grima
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Gene-gene interactions are crucial to the control of sub-cellular processes but our understanding of their stochastic dynamics is hindered by the lack of simulation methods that can accurately and efficiently predict how the distributions of
Externí odkaz:
https://doaj.org/article/e2d7cfdf203d49b097475aaaace2c468
Autor:
Szavits-Nossan, Juraj, Grima, Ramon
Stochastic models of gene expression are typically formulated using the chemical master equation, which can be solved exactly or approximately using a repertoire of analytical methods. Here, we provide a tutorial review of an alternative approach bas
Externí odkaz:
http://arxiv.org/abs/2307.03253
Autor:
Dudek, K. K., Mizzi, L., Martínez, J. A. Iglesias, Spaggiari, A., Ulliac, G., Gatt, R., Grima, J. N., Laude, V., Kadic, M.
Publikováno v:
Compos. Struct. 319, 117151 (2023)
The ability to control Poisson's ratio of functional materials has been one of the main objectives of researchers attempting to develop structures efficient from the perspective of protective, biomedical and soundproofing devices. This task becomes e
Externí odkaz:
http://arxiv.org/abs/2305.16766
Autor:
Szavits-Nossan, Juraj, Grima, Ramon
The telegraph model is the standard model of stochastic gene expression, which can be solved exactly to obtain the distribution of mature RNA numbers per cell. A modification of this model also leads to an analytical distribution of the nascent RNA n
Externí odkaz:
http://arxiv.org/abs/2304.05304
Autor:
Fatuma Seid Degu, Adem Hussein Endris, Samuel Anteneh Ayele, Natnaiel Grima Melkie, Mitaw Girma Kenbaw, Mekuriaw Wuhib Shumye, Missale Kassahun Hirpo, Atrsaw Dessie Liyew, Mandefro Assefaw Geremew, Prem Kumar
Publikováno v:
BMC Emergency Medicine, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Road traffic accidents(RTA) are a major public health problem worldwide, accounting for almost 1.24 million deaths per year and it is the number one cause of death among those aged group 15–29 years. Even though there are great
Externí odkaz:
https://doaj.org/article/83d1b41e228246869f2e444837771483