Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Grigory Maksaev"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Plants are challenged by drastically different osmotic environments during growth and development. Adaptation to these environments often involves mechanosensitive ion channels that can detect and respond to mechanical force. In the model pl
Externí odkaz:
https://doaj.org/article/2410a8b11db84261be9d4993b61d5654
Autor:
Grigory Maksaev, Michael Bründl-Jirout, Anna Stary-Weinzinger, Eva-Maria Zangerl-Plessl, Sun-Joo Lee, Colin G. Nichols
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Inwardly rectifying potassium (Kir) channels open at the ‘helix bundle crossing’ (HBC), formed by the M2 helices at the cytoplasmic end of the transmembrane pore. Introduced negative charges at the HBC (G178D) in Kir2.2 channels forces o
Externí odkaz:
https://doaj.org/article/13b6793a2f8e4b3ab216e0190876a3e2
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Mechanosensitive ion channels mediate biological force sensation, but the underlying mechanism remains poorly understood. Here, authors present the structural basis of mechanotransduction in an ion channel revealed by cryo-electron microscopy.
Externí odkaz:
https://doaj.org/article/d364dd7f082f49a9a860981e9bf52ba1
Autor:
Zengqin Deng, Grigory Maksaev, Angela M. Schlegel, Jingying Zhang, Michael Rau, James A. J. Fitzpatrick, Elizabeth S. Haswell, Peng Yuan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Mechanosensitive channels transduce physical force into electrochemical signaling in processes such as hearing, touch, proprioception, osmoregulation, and morphogenesis. Here, authors use cryo-electron microscopy to provide structural insights into t
Externí odkaz:
https://doaj.org/article/24278fd6df614c24883c81fc709a6580
Autor:
Thomas J. Kleist, I Winnie Lin, Sophia Xu, Grigory Maksaev, Mayuri Sadoine, Elizabeth S. Haswell, Wolf B. Frommer, Michael M. Wudick
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 787 (2022)
Interactions between physical forces and membrane proteins underpin many forms of environmental sensation and acclimation. Microbes survive osmotic stresses with the help of mechanically gated ion channels and osmolyte transporters. Plant mechanosens
Externí odkaz:
https://doaj.org/article/c46d1b019ae04916b48744b68d928911
Publikováno v:
Journal of General Physiology. 155
The Vanilloid thermoTRP (TRPV1–4) subfamily of TRP channels are involved in thermoregulation, osmoregulation, itch and pain perception, (neuro)inflammation and immune response, and tight control of channel activity is required for perception of nox
Autor:
Jingying Zhang, Tugba N. Ozturk, Grigory Maksaev, Michael J. Rau, James A.J. Fitzpatrick, Peng Yuan
Publikováno v:
Biophysical Journal. 122:192a-193a
Publikováno v:
Biophysical Journal. 122:109a
Autor:
Michael Bründl-Jirout, Grigory Maksaev, Sun Joo Lee, Anna Stary-Weinzinger, Eva-Maria Plessl, Colin G. Nichols
Publikováno v:
Biophysical Journal. 122:522a
Autor:
Jingying Zhang, James A. J. Fitzpatrick, Zengqin Deng, Peng Yuan, Grigory Maksaev, Angela M. Schlegel, Michael J. Rau, Elizabeth S. Haswell
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Nature Communications
Mechanosensitive ion channels transduce physical force into electrochemical signaling that underlies an array of fundamental physiological processes, including hearing, touch, proprioception, osmoregulation, and morphogenesis. The mechanosensitive ch