Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Grigory Dianov"'
Autor:
Angelos Papaspyropoulos, Leanne Bradley, Asmita Thapa, Chuen Yan Leung, Konstantinos Toskas, Delia Koennig, Dafni-Eleftheria Pefani, Cinzia Raso, Claudia Grou, Garth Hamilton, Nikola Vlahov, Anna Grawenda, Syed Haider, Jagat Chauhan, Ludovico Buti, Alexander Kanapin, Xin Lu, Francesca Buffa, Grigory Dianov, Alex von Kriegsheim, David Matallanas, Anastasia Samsonova, Magdalena Zernicka-Goetz, Eric O’Neill
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
In development, the switch from pluripotency to differentiation is important but it is often unclear how it is regulated. Here, the authors show that the tumour suppressor RASSF1A mediates this switch by promoting YAP-p73 transcription, which in turn
Externí odkaz:
https://doaj.org/article/851da86c94cb4859a74e3f6c31088f3a
Publikováno v:
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 347:57-62
Endogenous and environmental DNA-damaging agents often generate single-strand interruptions in DNA. The lesions trigger a complex set of cellular reactions. In most eukaryotic cells, cellular poly(ADPribose) formation is the most acute response to su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed7779af9bd42499b79a1eac37b119ea
https://doi.org/10.1098/rstb.1995.0009
https://doi.org/10.1098/rstb.1995.0009
Autor:
Tomas Lindahl, Grigory Dianov
Publikováno v:
Current Biology. 4:1069-1076
Background: The base excision–repair pathway is the major cellular defence mechanism against spontaneous DNA damage. The enzymes involved have been highly conserved during evolution. Base excision–repair has been reproduced previously with crude
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a31c5f2b553f95c51be767f54cd38e3
https://doi.org/10.1016/s0960-9822(00)00245-1
https://doi.org/10.1016/s0960-9822(00)00245-1
Publikováno v:
Molecular and Cellular Biology. 12:1605-1612
The extent and location of DNA repair synthesis in a double-stranded oligonucleotide containing a single dUMP residue have been determined. Gently prepared Escherichia coli and mammalian cell extracts were employed for excision repair in vitro. The s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08938e63b4c5a566688785cb3df99928
https://doi.org/10.1128/mcb.12.4.1605-1612.1992
https://doi.org/10.1128/mcb.12.4.1605-1612.1992
Publikováno v:
DNA Repair and Recombination ISBN: 9789401042390
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40813b9208f1643390300fc013bd9e4c
https://doi.org/10.1007/978-94-011-0537-8_8
https://doi.org/10.1007/978-94-011-0537-8_8
Autor:
Barbara Sedgwick, Susan T. Lovett, Monica Olsson, Graham Daly, Grigory Dianov, Tomas L. Lindahl
Publikováno v:
Scopus-Elsevier
Excision of deoxyribose-phosphate residues from enzymatically incised abasic sites in double-stranded DNA is required prior to gap-filling and ligation during DNA base excision-repair, and a candidate deoxyribophosphodiesterase (dRpase) activity has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a435bdb21ce251ccf1fda0cb2f17e66
https://europepmc.org/articles/PMC307920/
https://europepmc.org/articles/PMC307920/
Autor:
Tomas Lindahl, Grigory Dianov
Publikováno v:
Nucleic acids research. 19(14)
Double-stranded synthetic oligonucleotides with a centrally located dIMP residue in a 5'-32P-labeled strand were employed as substrates for hypoxanthine-DNA glycosylase. The enzyme activity was monitored by the generation of a piperidine-sensitive si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ab7f4fb2c77d9d9678847c7b12eb5b
https://pubmed.ncbi.nlm.nih.gov/1861976
https://pubmed.ncbi.nlm.nih.gov/1861976