Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Grigory A, Stepanov"'
Autor:
Victoria O. Shender, Ksenia S. Anufrieva, Polina V. Shnaider, Georgij P. Arapidi, Marat S. Pavlyukov, Olga M. Ivanova, Irina K. Malyants, Grigory A. Stepanov, Evgenii Zhuravlev, Rustam H. Ziganshin, Ivan O. Butenko, Olga N. Bukato, Ksenia M. Klimina, Vladimir A. Veselovsky, Tatiana V. Grigorieva, Sergey Y. Malanin, Olga I. Aleshikova, Andrey V. Slonov, Nataliya A. Babaeva, Lev A. Ashrafyan, Elena Khomyakova, Evgeniy G. Evtushenko, Maria M. Lukina, Zixiang Wang, Artemiy S. Silantiev, Anna A. Nushtaeva, Daria D. Kharlampieva, Vassili N. Lazarev, Arseniy I. Lashkin, Lorine K. Arzumanyan, Irina Yu. Petrushanko, Alexander A. Makarov, Olga S. Lebedeva, Alexandra N. Bogomazova, Maria A. Lagarkova, Vadim M. Govorun
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-26 (2024)
Abstract Ovarian cancer often develops resistance to conventional therapies, hampering their effectiveness. Here, using ex vivo paired ovarian cancer ascites obtained before and after chemotherapy and in vitro therapy-induced secretomes, we show that
Externí odkaz:
https://doaj.org/article/02b767c462a74d7a9e8af2b8a974a8fa
Autor:
Victoria O. Shender, Ksenia S. Anufrieva, Polina V. Shnaider, Georgij P. Arapidi, Marat S. Pavlyukov, Olga M. Ivanova, Irina K. Malyants, Grigory A. Stepanov, Evgenii Zhuravlev, Rustam H. Ziganshin, Ivan O. Butenko, Olga N. Bukato, Ksenia M. Klimina, Vladimir A. Veselovsky, Tatiana V. Grigorieva, Sergey Y. Malanin, Olga I. Aleshikova, Andrey V. Slonov, Nataliya A. Babaeva, Lev A. Ashrafyan, Elena Khomyakova, Evgeniy G. Evtushenko, Maria M. Lukina, Zixiang Wang, Artemiy S. Silantiev, Anna A. Nushtaeva, Daria D. Kharlampieva, Vassili N. Lazarev, Arseniy I. Lashkin, Lorine K. Arzumanyan, Irina Yu. Petrushanko, Alexander A. Makarov, Olga S. Lebedeva, Alexandra N. Bogomazova, Maria A. Lagarkova, Vadim M. Govorun
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/f7ef9cad5d454cc2baec5a64e3a1c416
Autor:
Artem G. Fedorovskiy, Denis N. Antropov, Anton S. Dome, Pavel A. Puchkov, Daria M. Makarova, Maria V. Konopleva, Anastasiya M. Matveeva, Eugenia A. Panova, Elena V. Shmendel, Mikhail A. Maslov, Sergey E. Dmitriev, Grigory A. Stepanov, Oleg V. Markov
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 684 (2024)
Over the past decade, mRNA-based therapy has displayed significant promise in a wide range of clinical applications. The most striking example of the leap in the development of mRNA technologies was the mass vaccination against COVID-19 during the pa
Externí odkaz:
https://doaj.org/article/fabd7a7db29d4126993439ce312d430e
Autor:
Denis N. Antropov, Grigory A. Stepanov
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 1, Pp 649-662 (2023)
Applied to investigate specific sequences, nucleic acid detection assays can help identify novel bacterial and viral infections. Most up-to-date systems combine isothermal amplification with Cas-mediated detection. They surpass standard PCR methods i
Externí odkaz:
https://doaj.org/article/255adfa947a2442a9dfa092d975b1bf9
Autor:
Maya A. Dymova, Natalia S. Vasileva, Elena V. Kuligina, Yulya I. Savinovskaya, Nikita D. Zinchenko, Alisa B. Ageenko, Sergey V. Mishinov, Grigory A. Stepanov, Vladimir A. Richter, Dmitry V. Semenov
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 11, Pp 5294-5311 (2022)
Glioblastoma multiforme (GBM) is one of the most highly metastatic cancers. The study of the pathogenesis of GBM, as well as the development of targeted oncolytic drugs, require the use of actual cell models, in particular, the use of 3D cultures or
Externí odkaz:
https://doaj.org/article/4fcd94e8ab31473f827c8fa59214aa02
Autor:
Dmitriy V. Semenov, Natalia S. Vasileva, Maya A. Dymova, Sergey V. Mishinov, Yulya I. Savinovskaya, Alisa B. Ageenko, Anton S. Dome, Nikita D. Zinchenko, Grigory A. Stepanov, Galina V. Kochneva, Vladimir A. Richter, Elena V. Kuligina
Publikováno v:
Cells, Vol 12, Iss 22, p 2616 (2023)
Oncolytic virotherapy is a rapidly evolving approach that aims to selectively kill cancer cells. We designed a promising recombinant vaccinia virus, VV-GMCSF-Lact, for the treatment of solid tumors, including glioma. We assessed how VV-GMCSF-Lact aff
Externí odkaz:
https://doaj.org/article/36347a003a8044acb5f012865faf38ee
Autor:
Natalia S. Vasileva, Elena V. Kuligina, Maya A. Dymova, Yulya I. Savinovskaya, Nikita D. Zinchenko, Alisa B. Ageenko, Sergey V. Mishinov, Anton S. Dome, Grigory A. Stepanov, Vladimir A. Richter, Dmitry V. Semenov
Publikováno v:
Cells, Vol 11, Iss 19, p 3106 (2022)
Glioma is the most common and heterogeneous primary brain tumor. The development of a new relevant preclinical models is necessary. As research moves from cultures of adherent gliomas to a more relevant model, neurospheres, it is necessary to underst
Externí odkaz:
https://doaj.org/article/7ff562c3990843ad859f998fc403d35c
Autor:
Anna A. Nushtaeva, Grigory A. Stepanov, Dmitry V. Semenov, Evgeny S. Juravlev, Evgenia A. Balahonova, Alexey V. Gerasimov, Sergey V. Sidorov, Eugeniy I. Savelyev, Elena V. Kuligina, Vladimir A. Richter, Olga A. Koval
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background The phenomenon of chemotherapy-resistant cancers has necessitated the development of new therapeutics as well as the identification of specific prognostic markers to predict the response to novel drugs. Primary cancer cells provid
Externí odkaz:
https://doaj.org/article/1ef39a4728c7463599df5740e289eca4
Autor:
Julia A. Filippova, Anastasiya M. Matveeva, Evgenii S. Zhuravlev, Evgenia A. Balakhonova, Daria V. Prokhorova, Sergey J. Malanin, Raihan Shah Mahmud, Tatiana V. Grigoryeva, Ksenia S. Anufrieva, Dmitry V. Semenov, Valentin V. Vlassov, Grigory A. Stepanov
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
CRISPR technologies are nowadays widely used for targeted knockout of numerous protein-coding genes and for the study of various processes and metabolic pathways in human cells. Most attention in the genome editing field is now focused on the cleavag
Externí odkaz:
https://doaj.org/article/db7e89ffdcf348808cadf52f37b9b273
Autor:
Ekaterina V. Starostina, Sergei V. Sharabrin, Denis N. Antropov, Grigory A. Stepanov, Georgiy Yu. Shevelev, Anna E. Lemza, Andrey P. Rudometov, Mariya B. Borgoyakova, Nadezhda B. Rudometova, Vasiliy Yu. Marchenko, Natalia V. Danilchenko, Anton N. Chikaev, Sergei I. Bazhan, Alexander A. Ilyichev, Larisa I. Karpenko
Publikováno v:
Vaccines, Vol 9, Iss 5, p 452 (2021)
Nucleic acid-based influenza vaccines are a promising platform that have recently and rapidly developed. We previously demonstrated the immunogenicity of DNA vaccines encoding artificial immunogens AgH1, AgH3, and AgM2, which contained conserved frag
Externí odkaz:
https://doaj.org/article/80426bd3388541168ee3c8be27c98539