Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Grigorios A. Papadakos"'
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 16:1269-1278
Understanding the roles of metal ions in restriction enzymes has been complicated by both the presence of two metal ions in many active sites and their homodimeric structure. Using a single-chain form of the wild-type restriction enzyme PvuII (scWT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fed1dd77c5bf8b43959ce48a8c1607e
https://doi.org/10.1007/s00775-011-0814-7
https://doi.org/10.1007/s00775-011-0814-7
Publikováno v:
Biochemistry. 47(47)
Ester hydrolysis is one of the most ubiquitous reactions in biochemistry. Many of these reactions rely on metal ions for various mechanistic steps. A large number of metal-dependent nucleases have been crystallized with two metal ions in their active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c2aeb8d20b8f650eb2d096aefe6b13
https://pubmed.ncbi.nlm.nih.gov/18975919
https://pubmed.ncbi.nlm.nih.gov/18975919
Publikováno v:
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 12(4)
The hydrolysis of phosphodiester bonds by nucleases is critical to nucleic acid processing. Many nucleases utilize metal ion cofactors, and for a number of these enzymes two active-site metal ions have been detected. Testing proposed mechanistic role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2f7e6c88064e3bb0ae28c86cf00810
https://pubmed.ncbi.nlm.nih.gov/17308914
https://pubmed.ncbi.nlm.nih.gov/17308914