Plasma Heme Scavengers Alpha-1-Microglobulin and Hemopexin as Biomarkers in High-Risk Pregnancies

Autor: Grigorios Kalapotharakos, Katja Murtoniemi, Bo Åkerström, Esa Hämäläinen, Eero Kajantie, Katri Räikkönen, Pia Villa, Hannele Laivuori, Stefan R. Hansson

Publikováno v: Frontiers in Physiology, Vol 10 (2019)

Women with established preeclampsia (PE) have increased plasma concentration of free fetal hemoglobin. We measured two hemoglobin scavenger system proteins, hemopexin (Hpx) and alpha-1-microglobulin (A1M) in maternal plasma using enzyme-linked immuno

Externí odkaz: https://doaj.org/article/546b3ede40dd49028586f50f986571ee

Corrigendum to 'Cardiovascular effects of severe late-onset preeclampsia are reversed within six months postpartum' [Preg. Hypertens. 19 (2020) 18–24]

Autor: Grigorios Kalapotharakos, Daniel Ryd, Katarina Steding-Ehrenborg, Maria E.V. Andersson, Håkan Arheden, Stefan R. Hansson, Erik Hedström

Publikováno v: Pregnancy Hypertension. 30:95

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc73fce42fc5965cd946c1880bd60b5a
https://doi.org/10.1016/j.preghy.2022.09.002

Alpha-1 microglobulin as a potential therapeutic candidate for treatment of hypertension and oxidative stress in the STOX1 preeclampsia mouse model

Autor: Grigorios Kalapotharakos, Erik Hedström, Lena Erlandsson, Stefan R. Hansson, Jean-Luc Vilotte, Daniel Vaiman, Johann Castille, Isac Zia, Aurélien Ducat

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (8561), pp.1-13. ⟨10.1038/s41598-019-44639-9⟩
Scientific Reports, 2019, 9 (8561), pp.1-13. ⟨10.1038/s41598-019-44639-9⟩
Scientific Reports 8561 (9), 1-13. (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)

Preeclampsia is a human placental disorder affecting 2–8% of pregnancies worldwide annually, with hypertension and proteinuria appearing after 20 weeks of gestation. The underlying cause is believed to be incomplete trophoblast invasion of the mate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d1f3c136f06af035fe1f2cdfffc101
https://doi.org/10.1038/s41598-019-44639-9

Fetal cardiac remodeling and dysfunction is associated with both preeclampsia and fetal growth restriction

Autor: Olga Gómez, Kilian Vellvé, Grigorios Kalapotharakos, Eduard Gratacós, Francesca Crovetto, Álvaro Sepúlveda-Martínez, L. Youssef, Cristina Paules, Fatima Crispi, Laura García-Otero, Jezid Miranda

Publikováno v: American Journal of Obstetrics and Gynecology. 222:79.e1-79.e9

Preeclampsia and fetal growth restriction share some pathophysiologic features and are both associated with placental insufficiency. Fetal cardiac remodeling has been described extensively in fetal growth restriction, whereas little is known about pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8945c49e695635dbf23ae7ccb92fe5
https://doi.org/10.1016/j.ajog.2019.07.025

202: Fetal cardiac remodeling associated with preeclampsia and fetal growth restriction

Autor: Eduard Gratacós, Grigorios Kalapotharakos, Álvaro Sepúlveda-Martínez, Francesca Crovetto, Kilian Vellvé, Laura García-Otero, L. Youssef, Cristina Paules, Jezid Miranda, Olga Leticia Fuchs Gómez, Fatima Crispi

Publikováno v: American Journal of Obstetrics and Gynecology. 220:S146-S147

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc929ebaebc2394e943142245d5529db
https://doi.org/10.1016/j.ajog.2018.11.223