Zobrazeno 1 - 10 of 1 699 pro vyhledávání: '"Grigoriadis DE"'
1
Akademický článek
Pharmacokinetic and Pharmacologic Characterization of the Dihydrotetrabenazine Isomers of Deutetrabenazine and Valbenazine.
Autor: Brar S; Neurocrine Biosciences, Inc., San Diego, California, USA., Vijan A; Neurocrine Biosciences, Inc., San Diego, California, USA., Scott FL; Neurocrine Biosciences, Inc., San Diego, California, USA., Jimenez R; Neurocrine Biosciences, Inc., San Diego, California, USA., Zhang H; Neurocrine Biosciences, Inc., San Diego, California, USA., Grigoriadis DE; Neurocrine Biosciences, Inc., San Diego, California, USA., Loewen G; Neurocrine Biosciences, Inc., San Diego, California, USA.
Publikováno v: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Apr; Vol. 12 (4), pp. 447-456. Date of Electronic Publication: 2022 Dec 18.
Zobrazit plný text záznamu
2
Akademický článek
Efficacy of Vesicular Monoamine Transporter 2 Inhibition and Synergy with Antipsychotics in Animal Models of Schizophrenia.
Autor: Hoare SRJ; Pharmechanics LLC, Owego, New York (S.R.J.H.); Neurocrine Biosciences, Inc., San Diego, California (A.E.K., D.E.G.); and Crinetics Pharmaceuticals Inc., San Diego, California (R.L.)., Kudwa AE; Pharmechanics LLC, Owego, New York (S.R.J.H.); Neurocrine Biosciences, Inc., San Diego, California (A.E.K., D.E.G.); and Crinetics Pharmaceuticals Inc., San Diego, California (R.L.)., Luo R; Pharmechanics LLC, Owego, New York (S.R.J.H.); Neurocrine Biosciences, Inc., San Diego, California (A.E.K., D.E.G.); and Crinetics Pharmaceuticals Inc., San Diego, California (R.L.)., Grigoriadis DE; Pharmechanics LLC, Owego, New York (S.R.J.H.); Neurocrine Biosciences, Inc., San Diego, California (A.E.K., D.E.G.); and Crinetics Pharmaceuticals Inc., San Diego, California (R.L.) dgrigoriadis@neurocrine.com.
Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2022 May; Vol. 381 (2), pp. 79-95. Date of Electronic Publication: 2022 Feb 23.
Zobrazit plný text záznamu
4
Akademický článek
Exploring the ability of the MD+FoldX method to predict SARS-CoV-2 antibody escape mutations using large-scale data.
Autor: Chi, L. América1 (AUTHOR), Barnes, Jonathan E.1 (AUTHOR), Patel, Jagdish Suresh1,2 (AUTHOR) jspatel@uidaho.edu, Ytreberg, F. Marty1,3 (AUTHOR) ytreberg@uidaho.edu
Publikováno v: Scientific Reports. 10/4/2024, Vol. 14 Issue 1, p1-16. 16p.
Zobrazit plný text záznamu
5
Akademický článek
Role of canonical and non-canonical cAMP sources in CRHR2α-dependent signaling.
Autor: Armando, Natalia G.1,2 (AUTHOR) narmando@ibioba-mpsp-conicet.gov.ar, dos Santos Claro, Paula A.1 (AUTHOR), Fuertes, Mariana1,3 (AUTHOR), Arzt, Eduardo1,3 (AUTHOR), Silberstein, Susana1 (AUTHOR) ssilberstein@ibioba-mpsp-conicet-gov.ar
Publikováno v: PLoS ONE. 10/02/2024, Vol. 19 Issue 10, p1-22. 22p.
Zobrazit plný text záznamu
6
Akademický článek
Effects of NBI-98782, a selective vesicular monoamine transporter 2 (VMAT2) inhibitor, on neurotransmitter efflux and phencyclidine-induced locomotor activity: Relevance to tardive dyskinesia and antipsychotic action.
Autor: Huang M; Departments of Psychiatry and Behavioral Sciences, Pharmacology, and Physiology, School of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States of America., He W; Departments of Psychiatry and Behavioral Sciences, Pharmacology, and Physiology, School of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States of America., Rajagopal L; Departments of Psychiatry and Behavioral Sciences, Pharmacology, and Physiology, School of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States of America., Kudwa A; Neurocrine Biosciences, Inc., San Diego, CA 921302007., Grigoriadis DE; Neurocrine Biosciences, Inc., San Diego, CA 921302007., Meltzer HY; Departments of Psychiatry and Behavioral Sciences, Pharmacology, and Physiology, School of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States of America. Electronic address: h-meltzer@northwestern.edu.
Publikováno v: Pharmacology, biochemistry, and behavior [Pharmacol Biochem Behav] 2020 Mar; Vol. 190, pp. 172872. Date of Electronic Publication: 2020 Feb 18.
Zobrazit plný text záznamu
7
Akademický článek
The importance of target binding kinetics for measuring target binding affinity in drug discovery: a case study from a CRF 1 receptor antagonist program.
Autor: Hoare SRJ; Pharmechanics LLC, 14 Sunnyside Drive South, Owego NY 13827, USA. Electronic address: sam.hoare@pharmechanics.com., Fleck BA; Neurocrine Biosciences Inc., 12780 El Camino Real, San Diego, CA 92130, USA., Williams JP; Neurocrine Biosciences Inc., 12780 El Camino Real, San Diego, CA 92130, USA., Grigoriadis DE; Neurocrine Biosciences Inc., 12780 El Camino Real, San Diego, CA 92130, USA.
Publikováno v: Drug discovery today [Drug Discov Today] 2020 Jan; Vol. 25 (1), pp. 7-14. Date of Electronic Publication: 2019 Sep 23.
Zobrazit plný text záznamu
8
Characterization and Regulation of Corticotropin-Releasing Factor Receptors in the Central Nervous, Endocrine and Immune Systems
Autor: De Souza Eb, Heroux Ja, Grigoriadis De
Publikováno v: Ciba Foundation Symposium 172-Corticotropin-Releasing Factor ISBN: 9780470514368
Ciba Foundation Symposium 172-Corticotropin-Releasing Factor
Corticotropin-releasing factor (CRF) plays a major role in coordinating the endocrine, autonomic, behavioural and immune responses to stress through actions in the brain and in the periphery. CRF receptors identified in brain, pituitary and spleen ha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74729e7dffa3f445674a06379e282d0f
https://doi.org/10.1002/9780470514368.ch5
Zobrazit plný text záznamu
9
Akademický článek
VMAT2 Inhibitors and the Path to Ingrezza (Valbenazine).
Autor: Harriott ND; Neurocrine Biosciences, San Diego, CA, United States., Williams JP; Neurocrine Biosciences, San Diego, CA, United States., Smith EB; Neurocrine Biosciences, San Diego, CA, United States., Bozigian HP; Neurocrine Biosciences, San Diego, CA, United States., Grigoriadis DE; Neurocrine Biosciences, San Diego, CA, United States.
Publikováno v: Progress in medicinal chemistry [Prog Med Chem] 2018; Vol. 57 (1), pp. 87-111. Date of Electronic Publication: 2018 Mar 07.
Zobrazit plný text záznamu
10
Akademický článek
Differences in Dihydrotetrabenazine Isomer Concentrations Following Administration of Tetrabenazine and Valbenazine.
Autor: Skor H; Neurocrine Biosciences, Inc., 12780 El Camino Real, San Diego, CA, 92130, USA. hskor@neurocrine.com., Smith EB; Neurocrine Biosciences, Inc., 12780 El Camino Real, San Diego, CA, 92130, USA., Loewen G; Neurocrine Biosciences, Inc., 12780 El Camino Real, San Diego, CA, 92130, USA., O'Brien CF; Neurocrine Biosciences, Inc., 12780 El Camino Real, San Diego, CA, 92130, USA., Grigoriadis DE; Neurocrine Biosciences, Inc., 12780 El Camino Real, San Diego, CA, 92130, USA., Bozigian H; Neurocrine Biosciences, Inc., 12780 El Camino Real, San Diego, CA, 92130, USA.
Publikováno v: Drugs in R&D [Drugs R D] 2017 Sep; Vol. 17 (3), pp. 449-459.
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje