Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Grigol Managadze"'
Publikováno v:
Pharmaceuticals, Vol 14, Iss 5, p 471 (2021)
Antimicrobial peptides (AMPs) are anti-infectives that have the potential to be used as a novel and untapped class of biotherapeutics. Modes of action of antimicrobial peptides include interaction with the cell envelope (cell wall, outer- and inner-m
Externí odkaz:
https://doaj.org/article/f12a3d1955fe4cbc9ee53f03c049b82b
Autor:
Boris Vishnepolsky, Maya Grigolava, Grigol Managadze, Andrei Gabrielian, Alex Rosenthal, Darrell E Hurt, Michael Tartakovsky, Malak Pirtskhalava
Publikováno v:
Brief Bioinform
The evolution of drug-resistant pathogenic microbial species is a major global health concern. Naturally occurring, antimicrobial peptides (AMPs) are considered promising candidates to address antibiotic resistance problems. A variety of computationa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cce33cdbcf4eb088f7cb6a144525de7
https://doi.org/10.1101/2022.01.28.478081
https://doi.org/10.1101/2022.01.28.478081
Publikováno v:
Pharmaceuticals
Pharmaceuticals, Vol 14, Iss 471, p 471 (2021)
Pharmaceuticals, Vol 14, Iss 471, p 471 (2021)
Antimicrobial peptides (AMPs) are anti-infectives that have the potential to be used as a novel and untapped class of biotherapeutics. Modes of action of antimicrobial peptides include interaction with the cell envelope (cell wall, outer- and inner-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd700e9fa4bf8fc50db10073e329e7f8
https://pubmed.ncbi.nlm.nih.gov/34067510
https://pubmed.ncbi.nlm.nih.gov/34067510
Autor:
Malak Pirtskhalava, Darrell E. Hurt, Andrei Gabrielian, Michael Tartakovsky, Grigol Managadze, Maia Grigolava, George I. Makhatadze, Alex Rosenthal, Boris Vishnepolsky
Publikováno v:
Journal of Chemical Information and Modeling. 58:1141-1151
Antimicrobial peptides (AMPs) have been identified as a potential new class of anti-infectives for drug development. There are a lot of computational methods that try to predict AMPs. Most of them can only predict if a peptide will show any antimicro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc8b4dee0289dc4c5c068fbb7f66999
https://doi.org/10.1021/acs.jcim.8b00118
https://doi.org/10.1021/acs.jcim.8b00118
Publikováno v:
Journal of biomolecular structuredynamics. 30(2)
Sequence alignment is a standard method for the estimation of the evolutionary, structural, and functional relationships among amino acid sequences. The quality of alignments depends on the used similarity matrix. Statistical contact potentials (CPs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2a90801f3974478eec6b379208cf499
https://pubmed.ncbi.nlm.nih.gov/22702729
https://pubmed.ncbi.nlm.nih.gov/22702729
Publikováno v:
Proteins. 71(4)
The present article describes residue level knowledge based potential SORDIS. SORDIS incorporates the information on side-chain orientation in relation to hydrophobic core centres, distance of residue from the globule centre and secondary structure.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72de00ebde36073ba54ca00a450f23f
https://pubmed.ncbi.nlm.nih.gov/18175309
https://pubmed.ncbi.nlm.nih.gov/18175309