Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Griffiths, Christopher EM"'
Autor:
Andres-Ejarque, Rosa, Ale, Hira Bahadur, Grys, Katarzyna, Tosi, Isabella, Solanky, Shane, Ainali, Chrysanthi, Catak, Zeynep, Sreeneebus, Hemawtee, Saklatvala, Jake, Dand, Nick, De Rinaldis, Emanuele, Chapman, Anna, Nestle, Frank O, Barnes, Michael R, Warren, Richard B, Reynolds, Nick J, Griffiths, Christopher EM, Barker, Jonathan N, Smith, Catherine H, Di Meglio, Paola, PSORT Consortium
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
Funder: Department of Health
Biologic therapies have transformed the management of psoriasis, but clinical outcome is variable leaving an unmet clinical need for predictive biomarkers of response. Here we perform in-depth immunomonitoring of blo
Biologic therapies have transformed the management of psoriasis, but clinical outcome is variable leaving an unmet clinical need for predictive biomarkers of response. Here we perform in-depth immunomonitoring of blo
Autor:
McCluskey, Daniel, Benzian-Olsson, Natashia, Mahil, Satveer K., Hassi, Nina Karoliina, Wohnhaas, Christian T., Burden, A David, Griffiths, Christopher EM., Ingram, John R., Levell, Nick J., Parslew, Richard, Pink, Andrew E., Reynolds, Nick J., Warren, Richard B., Visvanathan, Sudha, Baum, Patrick, Barker, Jonathan N., Smith, Catherine H., Capon, Francesca, Baudry, David, Cornelius, Victoria, Lachmann, Helen, McAteer, Helen, Meynell, Freya, Patel, Prakash, Pushparajah, Angela, Wilson, Rosemary
Publikováno v:
2022, ' Single-cell analysis implicates Th17 to Th2 cell plasticity in the pathogenesis of palmoplantar pustulosis ', Journal of Allergy and Clinical Immunology, vol. 150, no. 4, pp. 882-893 . https://doi.org/10.1016/j.jaci.2022.04.027
Background\ud\udPalmoplantar pustulosis (PPP) is a severe inflammatory skin disorder, characterised by eruptions of painful, neutrophil-filled pustules on the palms and soles. While PPP has a profound effect on quality of life, it remains poorly unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6b75dd1dc3871982dcc72708bc1b62
https://orca.cardiff.ac.uk/id/eprint/149924/1/McCluskey_et_al_submitted.pdf
https://orca.cardiff.ac.uk/id/eprint/149924/1/McCluskey_et_al_submitted.pdf
Autor:
Abo-Tabik, Maha, Parisi, Rosa, Morgan, Catharine, Willis, Sarah, Griffiths, Christopher EM, Ashcroft, Darren M
Publikováno v:
British Journal of General Practice; Nov2022, Vol. 72 Issue 724, pe834-e841, 8p
Publikováno v:
In The Lancet 21-27 July 2007 370(9583):263-271
Publikováno v:
In The Lancet 21-27 July 2007 370(9583):272-284
Autor:
Eckersley, Alexander, Mellody, Kieran T, Pilkington, Suzanne M, Griffiths, Christopher Em, Watson, Rachel E B, O'Cualain, Ronan, Baldock, Clair, Knight, David, Sherratt, Michael J
Publikováno v:
The Journal of Biological Chemistry
Eckersley, A, Mellody, K T, Pilkington, S M, Griffiths, C E, Watson, R E B, O'Cualain, R, Baldock, C, Knight, D & Sherratt, M J 2018, ' Structural and compositional diversity of fibrillin microfibrils in human tissues ', The Journal of biological chemistry, vol. 293, no. 14, pp. 5117-5133 . https://doi.org/10.1074/jbc.RA117.001483
Eckersley, A, Mellody, K T, Pilkington, S M, Griffiths, C E, Watson, R E B, O'Cualain, R, Baldock, C, Knight, D & Sherratt, M J 2018, ' Structural and compositional diversity of fibrillin microfibrils in human tissues ', The Journal of biological chemistry, vol. 293, no. 14, pp. 5117-5133 . https://doi.org/10.1074/jbc.RA117.001483
Elastic fibres comprising fibrillin microfibrils and elastin are present in many tissues, including the skin, lung, and arteries where they confer elasticity and resilience. Although fibrillin microfibrils play distinct and tissue-specific functional
Autor:
Reich, Kristian, Nestle, Frank O, Papp, Kim, Ortonne, Jean-Paul, Evans, Robert, Guzzo, Cynthia, Li, Shu, Dooley, Lisa T, Griffiths, Christopher EM
Publikováno v:
In The Lancet 2005 366(9494):1367-1374
Autor:
Thurstan Sarah A, Gibbs Neil K, Langton Abigail K, Griffiths Christopher EM, Watson Rachel EB, Sherratt Michael J
Publikováno v:
Chemistry Central Journal, Vol 6, Iss 1, p 34 (2012)
Abstract Human skin, in common with other organs, ages as a consequence of the passage of time, but in areas exposed to solar ultraviolet radiation, the effects of this intrinsic ageing process are exacerbated. In particular, both the severity and sp
Externí odkaz:
https://doaj.org/article/2cd7f56f9e1b408ab02bd08a1d989dd6
Autor:
Thorneloe, Rachael, Griffiths, Christopher EM, Emsley, Richard, Ashcroft, Darren M, Cordingley, Lis, Barker, Jonathan, Benham, Marilyn, Burden, David, Evans, Ian, Griffiths, Christopher, Hussain, Sagair, Kirby, Brian, Lawson, Linda, Mason, Kayleigh, McElhone, Kathleen, Murphy, Ruth, Ormerod, Anthony, Owen, Caroline, Reynolds, Nick, Smith, Catherine, Warren, Richard, Barnes, Michael, Payne, Katherine, Ryder, Samantha, Stocken, Deborah
Medication non-adherence is a missed opportunity for therapeutic benefit. We assessed “real-world” levels of self-reported non-adherence to conventional and biologic systemic therapies used for psoriasis and evaluated psychological and biomedical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::6d0df4400e1ede3e6b6e1cc071f7248e
Autor:
Aslam, Arif1, Griffiths, Christopher EM2 christopher.griffiths@manchester.ac.uk
Publikováno v:
Clinical Medicine. Feb2014, Vol. 14 Issue 1, p47-53. 7p.