Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Griffith D. Parks"'
Publikováno v:
Viruses, Vol 16, Iss 8, p 1270 (2024)
Natural killer (NK) cells can be effective immunotherapeutic anti-cancer agents due to their ability to selectively target and kill tumor cells. This activity is modulated by the interaction of NK cell receptors with inhibitory ligands on the surface
Externí odkaz:
https://doaj.org/article/5d77f5493d7548818ab809e97de35206
Autor:
Candace R. Fox, Kritika Kedarinath, Craig J. Neal, Jeremy Sheiber, Elayaraja Kolanthai, Udit Kumar, Christina Drake, Sudipta Seal, Griffith D. Parks
Publikováno v:
Molecules, Vol 28, Iss 13, p 5190 (2023)
There is intense interest in developing long-lasting, potent, and broad-spectrum antiviral disinfectants. Ceria nanoparticles (CNPs) can undergo surface redox reactions (Ce3+ ↔ Ce4+) to generate ROS without requiring an external driving force. Here
Externí odkaz:
https://doaj.org/article/1fbd6a640c7e4c1c88defc8509eaf4fb
Autor:
Kritika Kedarinath, Candace R. Fox, Erin Crowgey, Joseph Mazar, Peter Phelan, Tamarah J. Westmoreland, Kenneth A. Alexander, Griffith D. Parks
Publikováno v:
Viruses, Vol 14, Iss 8, p 1735 (2022)
Zika virus (ZIKV) exhibits distinct selectivity for infection of various cells and tissues, but how host cellular factors modulate varying permissivity remains largely unknown. Previous studies showed that the neuroblastoma cell line SK-N-AS (express
Externí odkaz:
https://doaj.org/article/9d59c6d8f4fc4c54bee4bdf15d6486aa
Autor:
Kritika Kedarinath, Griffith D. Parks
Publikováno v:
Pathogens, Vol 11, Iss 5, p 493 (2022)
The development of effective oncolytic viruses will require understanding the differences in virus replication and killing between normal and cancer cells. Here, we have evaluated infections of metastatic cancer (22Rv1) and benign non-tumorigenic (BP
Externí odkaz:
https://doaj.org/article/869162697e0547dd9a790c1351e3147e
Autor:
Candace R. Fox, Griffith D. Parks
Publikováno v:
Viruses, Vol 14, Iss 1, p 29 (2021)
Little is known about the role of complement (C’) in infections with highly prevalent circulating human coronaviruses such as OC43, a group of viruses of major public health concern. Treatment of OC43-infected human lung cells with human serum resu
Externí odkaz:
https://doaj.org/article/cfa954c4e1f6424a8a763533dbfbd181
Autor:
Maria A. Cruz, Griffith D. Parks
Publikováno v:
Viruses, Vol 12, Iss 3, p 253 (2020)
Resident cells in the skin serve as the first innate line of defense against insect-borne pathogens, but the role of these cell types in promoting or limiting arbovirus replication is not completely understood. Here, we have examined the outcome of i
Externí odkaz:
https://doaj.org/article/10e2ebeb2c274b8792b639a6e7ff3f10
Autor:
Candace R. Fox, Griffith D. Parks
Publikováno v:
Viruses, Vol 11, Iss 5, p 431 (2019)
Previous results have shown that infection with the cytoplasmic-replicating parainfluenza virus 5 mutant P/V-CPI- sensitizes cells to DNA damaging agents, resulting in the enhanced killing of airway cancer cells. Here, we have tested the hypothesis t
Externí odkaz:
https://doaj.org/article/dc47b8a9b09249e6b3422fa215212460
Autor:
Yujia Li, Griffith D. Parks
Publikováno v:
Viruses, Vol 10, Iss 5, p 219 (2018)
The complement system is a part of the innate immune system that viruses need to face during infections. Many viruses incorporate cellular regulators of complement activation (RCA) to block complement pathways and our prior work has shown that Parain
Externí odkaz:
https://doaj.org/article/424b84c208ae4ae987255a9fdc308fcc
Publikováno v:
Anti-Cancer Drugs.
Autor:
Udit Kumar, Candace R. Fox, Corbin Feit, Elayaraja Kolanthai, Jeremy Sheiber, Yifei Fu, Sushant Singh, Parag Banerjee, Griffith D. Parks, Sudipta Seal
Publikováno v:
RSC Advances. 12:19327-19339
The COVID-19 pandemic has underscored the importance of research and development in maintaining public health. Facing unprecedented challenges, the scientific community developed antiviral drugs, virucides, and vaccines to combat the infection within