Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Griffin Woolley"'
Autor:
Harikrishnan Balachandran, Kyle Kroll, Karen Terry, Cordelia Manickam, Rhianna Jones, Griffin Woolley, Tammy Hayes, Amanda J Martinot, Ankur Sharma, Mark Lewis, Stephanie Jost, R Keith Reeves
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012439 (2024)
Natural killer (NK) cells play a critical role in virus control. However, it has remained largely unclear whether NK cell mobilization in SARS-CoV-2 infections is beneficial or pathologic. To address this deficit, we employed a validated experimental
Externí odkaz:
https://doaj.org/article/6060b7066f3a4926857118d4855db1c9
Autor:
Cordelia Manickam, Amit A Upadhyay, Griffin Woolley, Kyle W Kroll, Karen Terry, Courtney A Broedlow, Nichole R Klatt, Steven E Bosinger, R Keith Reeves
Publikováno v:
PLoS Pathogens, Vol 20, Iss 5, p e1012223 (2024)
Natural killer-like B (NKB) cells are unique innate immune cells expressing both natural killer (NK) and B cell receptors. As first responders to infection, they secrete IL-18 to induce a critical cascade of innate and adaptive immune cell infiltrati
Externí odkaz:
https://doaj.org/article/66bb7e6cf16643e8817768d7427341ee
Autor:
Sho Sugawara, Brady Hueber, Griffin Woolley, Karen Terry, Kyle Kroll, Cordelia Manickam, Daniel R Ram, Lishomwa C Ndhlovu, Paul Goepfert, Stephanie Jost, R Keith Reeves
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011629 (2023)
Despite their importance, natural killer (NK) cell responses are frequently dysfunctional during human immunodeficiency virus-1 (HIV-1) and simian immunodeficiency virus (SIV) infections, even irrespective of antiretroviral therapies, with poorly und
Externí odkaz:
https://doaj.org/article/d835155fe136473c8794b99be669f303
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Natural killer (NK) cells represent a critical defense against viral infections and cancers. NK cells require integration of activating and inhibitory NK cell receptors to detect target cells and the balance of these NK cell inputs defines the global
Externí odkaz:
https://doaj.org/article/d04d71c6e75746489ef59242681661a3
Autor:
Kyle Kroll, Griffin Woolley, Karen Terry, Thomas Premeaux, Cecilia Shikuma, Michael Corley, Scott Bowler, Lishomwa Ndhlovu, R. Keith Reeves
Publikováno v:
AIDS Research and Human Retroviruses.
Autor:
Griffin Woolley, Matthew Mosher, Kyle Kroll, Rhianna Jones, Brady Hueber, Sho Sugawara, Cordelia Manickam, Karen Terry, Valerie Varner, Michelle Lifton, Daniel Ram, Christine M. Fennessey, Brandon F. Keele, R. Keith Reeves
Publikováno v:
J Virol
Natural killer (NK) cells are potent effector cells of the innate immune system possessing both cytotoxic and immunoregulatory capabilities, which contribute to their crucial role in controlling human immunodeficiency virus (HIV) and simian immunodef
Autor:
Kyle W. Kroll, Spandan V. Shah, Olivier A. Lucar, Thomas A. Premeaux, Cecilia M. Shikuma, Michael J. Corley, Matthew Mosher, Griffin Woolley, Scott Bowler, Lishomwa C. Ndhlovu, R. Keith Reeves
Publikováno v:
Cell reports. Medicine. 3(10)
Natural killer (NK) cells are critical modulators of HIV transmission and disease. Recent evidence suggests a loss of NK cell cytotoxicity during aging, yet analysis of NK cell biology and aging in people with HIV (PWH) is lacking. Herein, we perform
Autor:
Scott Smith, Rhianna Jones, Kyle Kroll, Daniel R. Ram, Spandan V. Shah, Griffin Woolley, Cordelia Manickam, R. Keith Reeves, Valerie Varner, Brady Hueber
Publikováno v:
Immunology
Granulocytes mediate broad immunoprotection through phagocytosis, extracellular traps, release of cytotoxic granules, antibody effector functions and recruitment of other immune cells against pathogens. However, descriptions of granulocytes in HIV in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb2f58bf1225501b03594f5928394ab
https://europepmc.org/articles/PMC8442246/
https://europepmc.org/articles/PMC8442246/
Autor:
Kyle Kroll, Rhianna Jones, Griffin Woolley, Spandan V. Shah, Scott Smith, Cordelia Manickam, R. Keith Reeves, Brady Hueber, Daniel R. Ram, Valerie Varner
Granulocytes mediate broad immunoprotection through phagocytosis, extracellular traps, release of cytotoxic granules, antibody effector functions and recruitment of other immune cells against pathogens. However, descriptions of granulocytes in HIV in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aad2b3de7c659ff06d8995faf7ede00
https://doi.org/10.1101/2021.03.19.436235
https://doi.org/10.1101/2021.03.19.436235
Autor:
Balachandran, Harikrishnan1 (AUTHOR), Kroll, Kyle1 (AUTHOR), Terry, Karen1 (AUTHOR), Manickam, Cordelia1 (AUTHOR), Jones, Rhianna1 (AUTHOR), Woolley, Griffin1 (AUTHOR), Hayes, Tammy2 (AUTHOR), Martinot, Amanda J.2 (AUTHOR), Sharma, Ankur3 (AUTHOR), Lewis, Mark3 (AUTHOR), Jost, Stephanie1 (AUTHOR), Reeves, R. Keith1,4 (AUTHOR) keith.reeves@duke.edu
Publikováno v:
PLoS Pathogens. 8/12/2024, Vol. 20 Issue 8, p1-20. 20p.