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Repurposing of lonafarnib as a treatment for SARS-CoV-2 infection.

Autor: Khan M; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, United States of America., Irvin P; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, United States of America., Park SB; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, United States of America., Ivester HM; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, United States of America., Ricardo-Lax I; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, United States of America., Leek M; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, United States of America., Grieshaber A; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, United States of America., Jang ES; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, United States of America., Coutermarsh-Ott SL; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, United States of America., Zhang Q; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, United States of America., Maio N; Eunice Kennedy Shriver National Institute of Child Health and Human Develop, NIH, Bethesda, United States of America., Jiang JK; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, United States of America., Li B; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, United States of America., Huang W; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, United States of America., Wang AQ; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, United States of America., Xu X; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, United States of America., Hu Z; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, United States of America., Zheng W; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, United States of America., Ye Y; Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, United States of America., Rouault T; Eunice Kennedy Shriver National Institute of Child Health and Human Develop, NIH, Bethesda, United States of America., Rice CM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, United States of America., Allen IC; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, United States of America., Liang TJ; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, United States of America.

Publikováno v: JCI insight [JCI Insight] 2024 Dec 03. Date of Electronic Publication: 2024 Dec 03.