Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Grier P Page"'
Autor:
Benjamin E Zuchelkowski, Ling Wang, Sebastien Gingras, Qinzi Xu, Minying Yang, Darrell Triulzi, Grier P Page, Victor R Gordeuk, Daniel B Kim-Shapiro, Janet S Lee, Mark T Gladwin
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240266 (2020)
BackgroundHydroxychloroquine (HCQ) is widely used in the treatment of malaria, rheumatologic disease such as lupus, and most recently, COVID-19. These uses raise concerns about its safe use in the setting of glucose-6-phosphate dehydrogenase (G6PD) d
Externí odkaz:
https://doaj.org/article/59567d7b2c6b4fc5bf6692d2b496f900
Autor:
Dana B Hancock, Joshua L Levy, Nathan C Gaddis, Laura J Bierut, Nancy L Saccone, Grier P Page, Eric O Johnson
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50610 (2012)
Genotype imputation, used in genome-wide association studies to expand coverage of single nucleotide polymorphisms (SNPs), has performed poorly in African Americans compared to less admixed populations. Overall, imputation has typically relied on Hap
Externí odkaz:
https://doaj.org/article/79425285b59c4a3eb373e4c3a187f24e
Autor:
Chuan-Yu Hsu, Joshua P Adams, Kyoungok No, Haiying Liang, Richard Meilan, Olga Pechanova, Abdelali Barakat, John E Carlson, Grier P Page, Cetin Yuceer
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45448 (2012)
CONSTANS (CO) is an important flowering-time gene in the photoperiodic flowering pathway of annual Arabidopsis thaliana in which overexpression of CO induces early flowering, whereas mutations in CO cause delayed flowering. The closest homologs of CO
Externí odkaz:
https://doaj.org/article/75e769adfdee428da1ef5c920b4f9065
Publikováno v:
PLoS Genetics, Vol 4, Iss 6, p e1000098 (2008)
Plasmode is a term coined several years ago to describe data sets that are derived from real data but for which some truth is known. Omic techniques, most especially microarray and genomewide association studies, have catalyzed a new zeitgeist of dat
Externí odkaz:
https://doaj.org/article/e8b0769d1fc146eaafe4ee16900cdf46
Autor:
Amy Moore, Jesse A. Marks, Bryan C. Quach, Yuelong Guo, Laura J. Bierut, Nathan C. Gaddis, Dana B. Hancock, Grier P. Page, Eric O. Johnson
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Where sufficiently large genome-wide association study (GWAS) samples are not currently available or feasible, methods that leverage increasing knowledge of the biological function of variants may illuminate discoveries without increasing sa
Externí odkaz:
https://doaj.org/article/94b3cb58479548ce83e501a5b657bb9f
Autor:
Fang Fang, Linran Zhou, Wei Perng, Carmen J. Marsit, Anna K. Knight, Andres Cardenas, Max T. Aung, Marie-France Hivert, Izzuddin M. Aris, Jaclyn M. Goodrich, Alicia K. Smith, Abigail Gaylord, Rebecca C. Fry, Emily Oken, George O’Connor, Douglas M. Ruden, Leonardo Trasande, Julie B. Herbstman, Carlos A. Camargo, Nicole R. Bush, Anne L. Dunlop, Dana M. Dabelea, Margaret R. Karagas, Carrie V. Breton, Carole Ober, Todd M. Everson, Grier P. Page, Christine Ladd-Acosta, on behalf of program collaborators for Environmental influences on Child Health Outcomes
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background Epigenetic clocks are promising tools for assessing biological age. We assessed the accuracy of pediatric epigenetic clocks in gestational and chronological age determination. Results Our study used data from seven tissue types on
Externí odkaz:
https://doaj.org/article/ba76599e9e1d4dfbacb72eaf17f477e9
Autor:
Lauren Petrick, Haibin Guan, Grier P. Page, Georgia Dolios, Megan M. Niedzwiecki, Robert O. Wright, Rosalind J. Wright
Publikováno v:
Environment International, Vol 187, Iss , Pp 108663- (2024)
Use of capillary blood devices for exposome research can deepen our understanding of the intricate relationship between environment and health, and open up new avenues for preventive and personalized medicine, particularly for vulnerable populations.
Externí odkaz:
https://doaj.org/article/bbea3ccd417743218a62ee0aa1975acc
Autor:
Maria Didriksen, Muhammad Sulaman Nawaz, Joseph Dowsett, Steven Bell, Christian Erikstrup, Ole B. Pedersen, Erik Sørensen, Poul J. Jennum, Kristoffer S. Burgdorf, Brendan Burchell, Adam S. Butterworth, Nicole Soranzo, David B. Rye, Lynn Marie Trotti, Prabhjyot Saini, Lilja Stefansdottir, Sigurdur H. Magnusson, Gudmar Thorleifsson, Thordur Sigmundsson, Albert P. Sigurdsson, Katja Van Den Hurk, Franke Quee, Michael W. T. Tanck, Willem H. Ouwehand, David J. Roberts, Eric J. Earley, Michael P. Busch, Alan E. Mast, Grier P. Page, John Danesh, Emanuele Di Angelantonio, Hreinn Stefansson, Henrik Ullum, Kari Stefansson
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-9 (2020)
Didriksen, Nawaz, et al. identify three novel genetic risk variants for restless legs syndrome and confirm 19 out of 20 previously reported variants through a genome-wide association meta-analysis including nearly half a million individuals. Using ex
Externí odkaz:
https://doaj.org/article/b804eef352554c768c94ad94c5a8a74a
Autor:
Aaron Issaian, Ariel Hay, Monika Dzieciatkowska, Domenico Roberti, Silverio Perrotta, Zsuzsanna Darula, Jasmina Redzic, Micheal P. Busch, Grier P. Page, Stephen C. Rogers, Allan Doctor, Kirk C. Hansen, Elan Z. Eisenmesser, James C. Zimring, Angelo D’Alessandro
Publikováno v:
Haematologica, Vol 106, Iss 11 (2021)
Band 3 (anion exchanger 1; AE1) is the most abundant membrane protein in red blood cells, which in turn are the most abundant cells in the human body. A compelling model posits that, at high oxygen saturation, the N-terminal cytosolic domain of AE1 b
Externí odkaz:
https://doaj.org/article/62266c7a47f34d6da98e2ad9ab1f4975
Autor:
Tamir Kanias, Marion C. Lanteri, Grier P. Page, Yuelong Guo, Stacy M. Endres, Mars Stone, Sheila Keating, Alan E. Mast, Ritchard G. Cable, Darrell J. Triulzi, Joseph E. Kiss, Edward L. Murphy, Steve Kleinman, Michael P. Busch, Mark T. Gladwin
Publikováno v:
Blood Advances, Vol 1, Iss 15, Pp 1132-1141 (2017)
Abstract: Genetic polymorphisms in blood donors may contribute to donor-specific differences in the survival of red blood cells (RBCs) during cold storage and after transfusion. Genetic variability is anticipated to be high in donors with racial admi
Externí odkaz:
https://doaj.org/article/4b37487facb4411ca6f6feb6165689bf