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Autor:
Müller, T.D., Finan, B., Bloom, S.R., D'Alessio, D., Drucker, D.J., Flatt, P.R., Fritsche, A., Gribble, F., Grill, H.J., Habener, J.F., Holst, J.J., Langhans, W., Meier, J.J., Nauck, M.A., Perez-Tilve, D., Pocai, A., Reimann, F., Sandoval, D.A., Schwartz, T.W., Seeley, R.J., Stemmer, K., Tang-Christensen, M., Woods, S.C., DiMarchi, R.D., Tschöp, M.H.
Publikováno v:
In Molecular Metabolism December 2019 30:72-130
Autor:
Adriaenssens A; Institute of Metabolic Science & MRC Metabolic Diseases Unit, University of Cambridge, Cambridge, United Kingdom.; Department of Neuroscience, Physiology, and Pharmacology, University College London, London, United Kingdom., Broichhagen J; Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany., de Bray A; Oxford Center for Diabetes, Endocrinology and Metabolism (OCDEM), NIHR Oxford Biomedical Research Center, Churchill Hospital, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.; Institute of Metabolism and Systems Research (IMSR) and Center of Membrane Proteins and Receptors (COMPARE), University of Birmingham, Birmingham, United Kingdom., Ast J; Oxford Center for Diabetes, Endocrinology and Metabolism (OCDEM), NIHR Oxford Biomedical Research Center, Churchill Hospital, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.; Institute of Metabolism and Systems Research (IMSR) and Center of Membrane Proteins and Receptors (COMPARE), University of Birmingham, Birmingham, United Kingdom., Hasib A; Institute of Metabolism and Systems Research (IMSR) and Center of Membrane Proteins and Receptors (COMPARE), University of Birmingham, Birmingham, United Kingdom., Jones B; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom., Tomas A; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom., Burgos NF; Department of Neuroscience, Physiology, and Pharmacology, University College London, London, United Kingdom., Woodward O; Institute of Metabolic Science & MRC Metabolic Diseases Unit, University of Cambridge, Cambridge, United Kingdom., Lewis J; Institute of Metabolic Science & MRC Metabolic Diseases Unit, University of Cambridge, Cambridge, United Kingdom., O'Flaherty E; Institute of Metabolic Science & MRC Metabolic Diseases Unit, University of Cambridge, Cambridge, United Kingdom., El K; Department of Medicine, Duke University Hospital, Durham, North Carolina, USA., Cui C; Department of Medicine, Duke University Hospital, Durham, North Carolina, USA., Harada N; Department of Diabetes, Endocrinology and Nutrition, Kyoto University, Kyoto, Japan., Inagaki N; Department of Diabetes, Endocrinology and Nutrition, Kyoto University, Kyoto, Japan., Campbell J; Department of Medicine, Duke University Hospital, Durham, North Carolina, USA., Brierley D; Department of Neuroscience, Physiology, and Pharmacology, University College London, London, United Kingdom., Hodson DJ; Oxford Center for Diabetes, Endocrinology and Metabolism (OCDEM), NIHR Oxford Biomedical Research Center, Churchill Hospital, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.; Institute of Metabolism and Systems Research (IMSR) and Center of Membrane Proteins and Receptors (COMPARE), University of Birmingham, Birmingham, United Kingdom., Samms R; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Gribble F; Institute of Metabolic Science & MRC Metabolic Diseases Unit, University of Cambridge, Cambridge, United Kingdom., Reimann F; Institute of Metabolic Science & MRC Metabolic Diseases Unit, University of Cambridge, Cambridge, United Kingdom.
Publikováno v:
JCI insight [JCI Insight] 2023 May 22; Vol. 8 (10). Date of Electronic Publication: 2023 May 22.
Autor:
Veprik A; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.; Novo Nordisk Research Centre Oxford, Oxford, UK., Denwood G; The Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Liu D; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.; Division of Systems Medicine, School of Medicine, University of Dundee, Dundee, Scotland, UK., Bany Bakar R; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Morfin V; Division of Systems Medicine, School of Medicine, University of Dundee, Dundee, Scotland, UK., McHugh K; School of Life Sciences, University of Dundee, Dundee, Scotland, UK., Tebeka NN; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.; Division of Systems Medicine, School of Medicine, University of Dundee, Dundee, Scotland, UK., Vetterli L; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Yonova-Doing E; Novo Nordisk Research Centre Oxford, Oxford, UK., Gribble F; Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Reimann F; Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Hoehn KL; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, Australia., Hemsley PA; School of Life Sciences, University of Dundee, Dundee, Scotland, UK.; Cell and Molecular Sciences, The James Hutton Institute, Dundee, Scotland, UK., Ahnfelt-Rønne J; Department of Pathology and Imaging, Novo Nordisk A/S, Måløv, Denmark., Rorsman P; The Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Zhang Q; The Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., de Wet H; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Cantley J; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK. jcantley001@dundee.ac.uk.; Division of Systems Medicine, School of Medicine, University of Dundee, Dundee, Scotland, UK. jcantley001@dundee.ac.uk.
Publikováno v:
Communications biology [Commun Biol] 2022 Mar 18; Vol. 5 (1), pp. 238. Date of Electronic Publication: 2022 Mar 18.
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Autor:
Patel, S., Alvarez-Guaita, A., Melvin, A., Rimmington, D., Dattilo, A., Miedzybrodzka, E. L., Cimino, I., Maurin, Anne-Catherine, Roberts, G. P., Meek, C. L., Virtue, S., Sparks, L. M., Parsons, S. A., Redman, L. M., Bray, G. A., Liou, A. P., Woods, R. M., Parry, S. A., Jeppesen, P. B., Kolnes, A. J., Harding, H. P., Ron, D., Vidal-Puig, A., Reimann, F., Gribble, F. M., Hulston, C. J., Farooqi, I. S., Fafournoux, Pierre, Smith, S. R., Jensen, J., Breen, D., Wu, Z., Zhang, B. B., Coll, A. P., Savage, D. B., O'Rahilly, S.
Publikováno v:
Cell Metabolism
Cell Metabolism, 2019, 29 (3), pp.707-718.e8. ⟨10.1016/j.cmet.2018.12.016⟩
Patel, S, Alvarez-Guaita, A, Melvin, A, Rimmington, D, Dattilo, A, Miedzybrodzka, E L, Cimino, I, Maurin, A C, Roberts, G P, Meek, C L, Virtue, S, Sparks, L M, Parsons, S A, Redman, L M, Bray, G A, Liou, A P, Woods, R M, Parry, S A, Jeppesen, P B, Kolnes, A J, Harding, H P, Ron, D, Vidal-Puig, A, Reimann, F, Gribble, F M, Hulston, C J, Farooqi, I S, Fafournoux, P, Smith, S R, Jensen, J, Breen, D, Wu, Z, Zhang, B B, Coll, A P, Savage, D B & O'Rahilly, S 2019, ' GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans ', Cell Metabolism, vol. 29, no. 3, pp. 707-718.e8 . https://doi.org/10.1016/j.cmet.2018.12.016
Cell Metabolism, Elsevier, 2019, Epub ahead of print, ⟨10.1016/j.cmet.2018.12.016⟩
Cell Metabolism, Elsevier, 2019, 29 (3), pp.707-718.e8. ⟨10.1016/j.cmet.2018.12.016⟩
Cell Metabolism, 2019, Epub ahead of print (3), ⟨10.1016/j.cmet.2018.12.016⟩
Cell Metabolism, Elsevier, 2019, Epub ahead of print (3), ⟨10.1016/j.cmet.2018.12.016⟩
Cell Metabolism, 2019, 29 (3), pp.707-718.e8. ⟨10.1016/j.cmet.2018.12.016⟩
Patel, S, Alvarez-Guaita, A, Melvin, A, Rimmington, D, Dattilo, A, Miedzybrodzka, E L, Cimino, I, Maurin, A C, Roberts, G P, Meek, C L, Virtue, S, Sparks, L M, Parsons, S A, Redman, L M, Bray, G A, Liou, A P, Woods, R M, Parry, S A, Jeppesen, P B, Kolnes, A J, Harding, H P, Ron, D, Vidal-Puig, A, Reimann, F, Gribble, F M, Hulston, C J, Farooqi, I S, Fafournoux, P, Smith, S R, Jensen, J, Breen, D, Wu, Z, Zhang, B B, Coll, A P, Savage, D B & O'Rahilly, S 2019, ' GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans ', Cell Metabolism, vol. 29, no. 3, pp. 707-718.e8 . https://doi.org/10.1016/j.cmet.2018.12.016
Cell Metabolism, Elsevier, 2019, Epub ahead of print, ⟨10.1016/j.cmet.2018.12.016⟩
Cell Metabolism, Elsevier, 2019, 29 (3), pp.707-718.e8. ⟨10.1016/j.cmet.2018.12.016⟩
Cell Metabolism, 2019, Epub ahead of print (3), ⟨10.1016/j.cmet.2018.12.016⟩
Cell Metabolism, Elsevier, 2019, Epub ahead of print (3), ⟨10.1016/j.cmet.2018.12.016⟩
Summary GDF15 is an established biomarker of cellular stress. The fact that it signals via a specific hindbrain receptor, GFRAL, and that mice lacking GDF15 manifest diet-induced obesity suggest that GDF15 may play a physiological role in energy bala
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597eddd3d02767a85945b3887b888c98
https://hal.inrae.fr/hal-02952242
https://hal.inrae.fr/hal-02952242
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