Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Grewo, Lim"'
Autor:
Jiajia Dai, Hyangin Kim, Zerong You, Michael F. McCabe, Shuzhuo Zhang, Shiyu Wang, Grewo Lim, Lucy Chen, Jianren Mao
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The reduced antidepressant and antihyperalgesic effects of selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine during maintenance treatment has been reported, but little is known about the molecular mechanism of this phenomenon. In thr
Externí odkaz:
https://doaj.org/article/de864ada10de4337b218cde94cab6a09
Autor:
Grewo Lim, Jiamin Miao, Weihua Ding, Jianren Mao, Lucy Chen, Jinsheng Yang, Liuyue Yang, Shiqian Shen, Jason T Doheny, Zerong You
Publikováno v:
Anesthesia & Analgesia. 129:890-895
As opioid abuse and addiction have developed into a major national health crisis, prescription of opioids for pain management has become more controversial. However, opioids do help some patients by providing pain relief and improving the quality of
Autor:
Grewo Lim, Shiqian Shen, Zerong You, Jianren Mao, Jason T Doheny, Weihua Ding, Lucy Chen, Jinsheng Yang, Yi Zhang, Shengmei Zhu
Publikováno v:
The Journal of Pain. 19:626-634
Orofacial neuropathic pain caused by trigeminal nerve injury is a debilitating condition with limited therapeutic options. Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels regulate neuronal excitability and are involved in the devel
Autor:
Zerong You, Liuyue Yang, Grewo Lim, Weihua Ding, Samuel Tate, Shuzhuo Zhang, Jinsheng Yang, Jianren Mao, Shiqian Shen, Lucy Chen, Jason T Doheny
Publikováno v:
Pain. 159:1518-1528
Clinical evidence indicates that cognitive impairment is a common comorbid condition of chronic pain. However, the cellular basis for chronic pain-mediated cognitive impairment remains unclear. We report here that rats exhibited memory deficits after
Publikováno v:
IUBMB Life. 70:143-152
Neuropathic pain is a complex, chronic pain condition and the treatment is a major clinical challenge. Recent studies have shown that two FDA approved drugs dexmedetomidine (DEX) and midazolam (MZL), may be useful in treating neuropathic pain, but th
Autor:
Shiqian Shen, Grewo Lim, Zerong You, Michael F. McCabe, Samuel Tate, Douglas S. Kwon, Chongzhao Ran, Weihua Ding, Peigen Huang, Kun Hu, Jason T Doheny, Hyangin Kim, Lucy Chen, Jianren Mao, Bo Huang, Zhongcong Xie, Peter Caravan
Publikováno v:
Nature neuroscience
Chemotherapy-induced pain is a dose-limiting condition that affects 30% of patients undergoing chemotherapy. We found that the gut microbiota promotes the development of chemotherapy-induced mechanical hyperalgesia. Oxaliplatin-induced mechnical hype
Autor:
Gregory R Wotjkiewicz, Shiqian Shen, Ranliang Hu, Jianren Mao, Weihua Ding, Grewo Lim, Sarah Roth, John W. Chen, Arissa Opalacz, Lucy Chen, Zerong You, Shihab U. Ahmed, Yi Zhang
Publikováno v:
Pain medicine (Malden, Mass.). 19(4)
ObjectiveCorrelation between radiologic structural abnormalities and clinical symptoms in low back pain patients is poor. There is an unmet clinical need to image inflammation in pain conditions to aid diagnosis and guide treatment. Ferumoxytol, an u
Autor:
Wenli Mi, Grewo Lim, Jianren Mao, Hyangin Kim, Lucy Chen, Zerong You, Shuxing Wang, Michael F. McCabe
Combination drug therapy is commonly used to treat chronic pain conditions such as neuropathic pain, and antidepressant is often used together with opioid analgesics. While rewarding is an intrinsic property of opioid analgesics, it is unknown whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18355c4df79626ff27bce4befa34cee4
https://europepmc.org/articles/PMC5561460/
https://europepmc.org/articles/PMC5561460/
Autor:
Jiayu, Chen, Hanjun, Li, Grewo, Lim, Michael F, McCabe, Wei, Zhao, Yunli, Yang, Weiqing, Ma, Na, Li
Publikováno v:
IUBMB life. 70(2)
Neuropathic pain is a complex, chronic pain condition and the treatment is a major clinical challenge. Recent studies have shown that two FDA approved drugs dexmedetomidine (DEX) and midazolam (MZL), may be useful in treating neuropathic pain, but th
Publikováno v:
NeuroImage. 174
Methamphetamine (meth), and other psychostimulants such as cocaine, present a persistent problem for society with chronic users being highly prone to relapse. We show, in a chronic methamphetamine administration model, that discontinuation of drug fo