M-CSF Priming of Osteoclast Precursors Can Cause Osteoclastogenesis-Insensitivity, Which Can be Prevented and Overcome on Bone

Autor: de Vries, TJ, Schoenmaker, T, Aerts, D, Grevers, LC, Souza, PPC, Nazmi, K, van de Wiel, MA, Ylstra, B, van Lent, PL, Leenen, Pieter, Everts, V

Publikováno v: de Vries, T J, Schoenmaker, T, Aerts, D, Grevers, L C, Souza, P P C, Nazmi, K, van de Wiel, M A, Ylstra, B, van Lent, P L, Leenen, P J M & Everts, V 2015, ' M-CSF Priming of Osteoclast Precursors Can Cause Osteoclastogenesis-Insensitivity, Which Can be Prevented and Overcome on Bone ', Journal of Cellular Physiology, vol. 230, no. 1, pp. 210-225 . https://doi.org/10.1002/jcp.24702
Journal of Cellular Physiology, 230(1), 210-225. Wiley-Liss Inc.
de Vries, T J, Schoenmaker, T, Aerts, D, Grevers, L C, Souza, P P C, Nazmi, K, van de Wiel, M A, Ylstra, B, van Lent, P L, Leenen, P J M & Everts, V 2015, ' M-CSF priming of osteoclast precursors can cause osteoclastogenesis-insensitivity, which can be prevented and overcome on bone ', Journal of Cellular Physiology, vol. 230, no. 1, pp. 210-225 . https://doi.org/10.1002/jcp.24702

Osteoclasts and macrophages share progenitors that must receive decisive lineage signals driving them into their respective differentiation routes. Macrophage colony stimulation factor M-CSF is a common factor; bone is likely the stimulus for osteocl

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https://research.vumc.nl/en/publications/5843d983-caef-45bd-baaf-79199b3afff9

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