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Effect of the structure of adenosine mimic of bisubstrate-analog inhibitors on their activity towards basophilic protein kinases

Autor: Mart Roben, Asko Uri, Gerda Raidaru, Marie Kriisa, Grete Kadak, Erki Enkvist

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 19:6098-6101

Previously reported structural fragments that associate with the ATP-binding pocket of basophilic protein kinases were conjugated with d-arginine-containing peptides. Inhibitory potency of the resulting bisubstrate-analog inhibitors towards PKA and R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6485aa17014f32f252d4129d1c051080
https://doi.org/10.1016/j.bmcl.2009.09.026

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