Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Gretchen M. Ehrenkaufer"'
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-18 (2020)
Abstract Background The RNA interference (RNAi) pathway is a gene regulation mechanism that utilizes small RNA (sRNA) and Argonaute (Ago) proteins to silence target genes. Our previous work identified a functional RNAi pathway in the protozoan parasi
Externí odkaz:
https://doaj.org/article/98ea66793cae41d3aba6c2b74f641a68
Autor:
Monica M. Kangussu-Marcolino, Gretchen M. Ehrenkaufer, Emily Chen, Anjan Debnath, Upinder Singh
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 11, Iss , Pp 80-94 (2019)
The free-living amebae Naegleria, Acanthamoeba, and Balamuthia cause rare but life-threatening infections. All three parasites can cause meningoencephalitis. Acanthamoeba can also cause chronic keratitis and both Balamuthia and Acanthamoeba can cause
Externí odkaz:
https://doaj.org/article/246cf7eb190844069f7ed6ba46f4fff9
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Neglected tropical diseases, especially those caused by parasites, are significantly underserved by current drug development efforts, mostly due to the high costs and low economic returns. One method for lowering the costs of drug discovery and devel
Externí odkaz:
https://doaj.org/article/516291b07f9041c1bf515882b0e479ed
Publikováno v:
Curr Opin Microbiol
Entamoeba histolytica, an anaerobic protozoan, is an important global health problem. This parasite has a biphasic life cycle consisting of a dormant cyst stage which is environmentally resistant and transmits the infection, and the proliferative tro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ce296ae9a3f74ba02778cedeede9b8
https://doi.org/10.1016/j.mib.2020.09.005
https://doi.org/10.1016/j.mib.2020.09.005
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-18 (2020)
BMC Genomics
BMC Genomics
Background The RNA interference (RNAi) pathway is a gene regulation mechanism that utilizes small RNA (sRNA) and Argonaute (Ago) proteins to silence target genes. Our previous work identified a functional RNAi pathway in the protozoan parasite Entamo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b234bbe55f2c6222b518e7a7f60387
https://doaj.org/article/98ea66793cae41d3aba6c2b74f641a68
https://doaj.org/article/98ea66793cae41d3aba6c2b74f641a68
Entamoeba histolytica is a disease-causing parasitic amoeba which affects an estimated 50 million people worldwide, particularly in socioeconomically vulnerable populations experiencing water sanitation issues. Infection with E. histolytica is referr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7713cc7a704bb45c2ace9cefa4f8ec5a
https://doi.org/10.1101/2021.10.06.463301
https://doi.org/10.1101/2021.10.06.463301
Stress response in Entamoeba histolytica is associated with robust processing of tRNA to tRNA-halves
tRNA-derived fragments have been reported in many different organisms and have diverse cellular roles such as regulating gene expression, inhibiting protein translation, silencing transposable elements and modulating cell proliferation. In particular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36e8592e3854d3aad2fbd1cee32e7da8
https://doi.org/10.1101/2021.09.30.462689
https://doi.org/10.1101/2021.09.30.462689
Autor:
Emily I. Chen, Gretchen M. Ehrenkaufer, Monica M. Kangussu-Marcolino, Upinder Singh, Anjan Debnath
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 11, Iss, Pp 80-94 (2019)
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance
The free-living amebae Naegleria, Acanthamoeba, and Balamuthia cause rare but life-threatening infections. All three parasites can cause meningoencephalitis. Acanthamoeba can also cause chronic keratitis and both Balamuthia and Acanthamoeba can cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669304634cb0fe4aed5cfee1f1ee6959
http://www.sciencedirect.com/science/article/pii/S2211320719301022
http://www.sciencedirect.com/science/article/pii/S2211320719301022
Publikováno v:
PLoS neglected tropical diseases, vol 15, iss 2
PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0008425 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0008425 (2021)
PLoS Neglected Tropical Diseases
Entamoeba histolytica is a protozoan parasite which infects approximately 50 million people worldwide, resulting in an estimated 70,000 deaths every year. Since the 1960s E. histolytica infection has been successfully treated with metronidazole. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40fa43a7b4d8993c2d69f82700d30e3
https://escholarship.org/uc/item/0tz4754w
https://escholarship.org/uc/item/0tz4754w
Background: The RNA interference (RNAi) pathway is a gene regulation mechanism that uitilizes small RNA (sRNA) and Argonaute (Ago) proteins to silence target genes. Our previous work identified a functional RNAi pathway in the protozoan parasite Enta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd824f122f72be3894305173754c6fe5
https://doi.org/10.21203/rs.3.rs-41465/v1
https://doi.org/10.21203/rs.3.rs-41465/v1