Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Gretchen L. Snyder"'
Autor:
Keivan Golshiri, Ehsan Ataei Ataabadi, Annika A. Jüttner, Gretchen L. Snyder, Robert E Davis, Amy Lin, Lei Zhang, René de Vries, Ingrid M Garrelds, Frank P. J. Leijten, A. H. Jan Danser, Anton J. M. Roks
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Age-related cardiovascular diseases (CVDs) remain among the leading global causes of death, and vascular smooth muscle cell (VSMC) remodeling plays an essential role in its pathology. Reduced NO-cGMP pathway signaling is a major feature and pathogeni
Externí odkaz:
https://doaj.org/article/432cd51823f34d07a3f3d4c35f7842bb
Autor:
Akinori Nishi, Gretchen L. Snyder
Publikováno v:
Journal of Pharmacological Sciences, Vol 114, Iss 1, Pp 6-16 (2010)
Dopamine plays a central role in the regulation of psychomotor functions. The effect of dopamine is largely mediated through the cAMP/PKA signaling cascade and therefore controlled by phosphodiesterases (PDEs). Multiple PDEs with different substrate
Externí odkaz:
https://doaj.org/article/983e66bcba3b42eca93648930c29d50e
Publikováno v:
The Journal of Neuroscience. 43:863-877
Lumateperone is indicated for the treatment of schizophrenia in adults and for depressive episodes associated with bipolar I or II disorder (bipolar depression) in adults, as monotherapy and as adjunctive therapy with lithium or valproate (Calabrese
Publikováno v:
Cancer Research. 83:487-487
Breast cancer is the most common cancer in women. Unfortunately, some patients do not benefit from most therapies and may even develop resistance to previously effective treatments leading to disease progression. Therefore, treatment resistance remai
Autor:
Keivan Golshiri, Ehsan Ataei Ataabadi, Annika A. Jüttner, Gretchen L. Snyder, Robert E Davis, Amy Lin, Lei Zhang, René de Vries, Ingrid M Garrelds, Frank P. J. Leijten, A. H. Jan Danser, Anton J. M. Roks
Publikováno v:
Frontiers in Pharmacology, 12:818355. Frontiers Media S.A.
Frontiers in Pharmacology, Vol 12 (2022)
Frontiers in Pharmacology, Vol 12 (2022)
Age-related cardiovascular diseases (CVDs) remain among the leading global causes of death, and vascular smooth muscle cell (VSMC) remodeling plays an essential role in its pathology. Reduced NO-cGMP pathway signaling is a major feature and pathogeni
Autor:
Robert E. Davis, Wei Yao, Ingrid van der Pluijm, Antoinette MaassenVanDenBrink, Eloísa Rubio-Beltrán, Ingrid M. Van den Berg-Garrelds, Renata M. C. Brandt, A.H. Jan Danser, Sophie Dutheil, Gretchen L. Snyder, René de Vries, Ehsan Ataei Ataabadi, Keivan Golshiri, Anton J.M. Roks
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics, 378(2), 173-183. American Society for Pharmacology and Experimental Therapeutics
Diminished nitric oxide-cGMP-mediated relaxation plays a crucial role in cardiovascular aging, leading to decreased vasodilation, vascular hypertrophy and stiffening, and ultimately, cardiovascular dysfunction. Aging is the time-related worsening of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07ac192bf1862526ed9444873a9d8b1
https://pure.eur.nl/en/publications/c4405b4e-c6b5-442b-b880-033b5acf6f71
https://pure.eur.nl/en/publications/c4405b4e-c6b5-442b-b880-033b5acf6f71
Publikováno v:
Cancer Research. 82:2577-2577
Breast cancer is the most common cancer in women. Targeted therapies, such as hormonotherapy or immunotherapy, including checkpoint inhibitors, have revolutionized cancer treatment and are effective for most breast cancer patients. Unfortunately, som
A review of the pharmacology and clinical profile of lumateperone for the treatment of schizophrenia
Autor:
Gretchen L, Snyder, Kimberly E, Vanover, Robert E, Davis, Peng, Li, Allen, Fienberg, Sharon, Mates
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 90
Schizophrenia is associated with a tremendous individual and societal burden. The disease is characterized by a complex set of symptoms including psychosis, hallucinations, delusions and related positive symptoms combined with social function deficit
Autor:
Annika Jüttner, Sophie Dutheil, Ingrid van der Pluijm, Robert E. Davis, Gretchen L. Snyder, Ehsan Ataei Ataabadi, René de Vries, A.H. Jan Danser, Martine de Boer, Anton J.M. Roks, Keivan Golshiri, Dirk J. Duncker, Richard van Veghel, Janette van der Linden, Amy Lin, Lei Zhang, Suman Chalgeri
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity, 2021:2308317. Hindawi Publishing Corporation
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, 2021:2308317. Hindawi Publishing Corporation
Oxidative Medicine and Cellular Longevity
Persistently unrepaired DNA damage has been identified as a causative factor for vascular ageing. We have previously shown that a defect in the function or expression of the DNA repair endonuclease ERCC1 (excision repair cross complement 1) in mice l
A review of the pharmacology and clinical profile of lumateperone for the treatment of schizophrenia
Autor:
Gretchen L. Snyder, Peng Li, Robert E. Davis, Sharon Mates, Kimberly E. Vanover, Allen A. Fienberg
Publikováno v:
A Tribute to Paul Greengard (1925-2019) ISBN: 9780128225165
Schizophrenia is associated with a tremendous individual and societal burden. The disease is characterized by a complex set of symptoms including psychosis, hallucinations, delusions and related positive symptoms combined with social function deficit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ac6e5c1ac264ecc9af1a992429900e0
https://doi.org/10.1016/bs.apha.2020.09.001
https://doi.org/10.1016/bs.apha.2020.09.001