Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gretchen E. Parker"'
Autor:
Gretchen E Parker
Publikováno v:
Cureus
The treatment therapies and technologies currently emerging from the rapidly evolving health care industry must undergo full examination in a clinical setting if they are to be marketed to the public. All elements of clinical studies involving human
Publikováno v:
Journal of Cellular Biochemistry. 94:67-80
LHX3 is a LIM homeodomain transcription factor with essential roles in pituitary and motor neuron development in mammals. Patients with mutations in the LHX3 gene have combined pituitary hormone deficiency and other symptoms. In this study, we show t
Publikováno v:
Current Genomics. 2:379-397
Autor:
Willem J. Els, Carla J. Faletti, Bonnie L. Blazer-Yost, Michael B. Butterworth, Gretchen E. Parker, Simon J. Rhodes, Amy D. Hartman
Publikováno v:
American Journal of Physiology-Cell Physiology. 281:C624-C632
A6 model renal epithelial cells were stably transfected with enhanced green fluorescent protein (EGFP)-tagged α- or β-subunits of the epithelial Na+channel (ENaC). Transfected RNA and proteins were both expressed in low abundance, similar to the en
Autor:
Pasutha Thunyakitpisal, Simon J. Rhodes, Kitti Torrungruang, Gretchen E. Parker, Hilary A. Feister, Joseph P. Bidwell
Publikováno v:
Journal of Cellular Biochemistry. 79:506-517
The mechanisms underlying the coupling of type I collagen and matrix metalloproteinase (MMP) expression to cell structure and adhesion are poorly understood. We propose that nuclear matrix architectural transcription factors link cell structure and t
Autor:
Peter J. Roach, Wei Wang, Alexander V. Skurat, Gretchen E. Parker, Anna A. DePaoli-Roach, Nina Raben
Publikováno v:
Biochemical and biophysical research communications. 350(3)
Laforin, encoded by the EPM2A gene, is a dual specificity protein phosphatase that has a functional glycogen-binding domain. Mutations in the EPM2A gene account for around half of the cases of Lafora disease, an autosomal recessive neurodegenerative
Autor:
Mariko Obayashi, Robert A. Harris, Jill M. Schroeder, Bartholomew A. Pederson, Gretchen E. Parker, Peter J. Roach
Publikováno v:
The Biochemical journal. 395(1)
Glycogen, a branched polymer of glucose, forms an energy re-serve in numerous organisms. In mammals, the two largest glyco-gen stores are in skeletal muscle and liver, which express tissue-specific glycogen synthase isoforms. MGSKO mice, in which mGy
Autor:
Peter J. Roach, Jill M. Schroeder, Bartholomew A. Pederson, Gretchen E. Parker, Anna A. DePaoli-Roach, Micah W. Smith
Publikováno v:
Diabetes. 54(12)
Glycogen is an important component of whole-body glucose metabolism. MGSKO mice lack skeletal muscle glycogen due to disruption of the GYS1 gene, which encodes muscle glycogen synthase. MGSKO mice were 5–10% smaller than wild-type littermates with
Autor:
Kyle W. Sloop, Brooke E. West, Gretchen E. Parker, Lisa R. Beach, Parinda Kiratipranon, Katherine S. Toomey, Stephanie C. Colvin, Jesse J. Savage, Simon J. Rhodes
Publikováno v:
Endocrinology. 145(11)
FSH is a critical hormone regulator of gonadal function that is secreted from the pituitary gonadotrope cell. Human patients and animal models with mutations in the LHX3 LIM-homeodomain transcription factor gene exhibit complex endocrine diseases, in
Publikováno v:
Developmental Endocrinology ISBN: 9781468496635
The hypothalamic-pituitary (H-P) axis regulates many aspects of mammalian endocrine physiology by the controlled secretion of hormones. The hypothalamus is part of the diencephalon at the base of the brain beneath the third ventricle (1). It is physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f060a988ec595a45eceb154e164d7f
https://doi.org/10.1385/1-59259-156-6:03
https://doi.org/10.1385/1-59259-156-6:03